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    SUBSTITUTE DIPHENYLAMINE COMPOUNDS USE THEREOF AS ANTITUMOR AGENTS
    6.
    发明申请
    SUBSTITUTE DIPHENYLAMINE COMPOUNDS USE THEREOF AS ANTITUMOR AGENTS 有权
    替代二苯胺化合物作为抗菌剂使用

    公开(公告)号：US20150011628A1

    公开(公告)日：2015-01-08

    申请号：US14376074

    申请日：2013-03-06

    申请人： SINOCHEM CORPORATION ,  SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.

    发明人： Changling Liu ,  Baoshan Chai ,  Huichao Li ,  Aiying Guan

    IPC分类号： C07C255/58 ,  C07C205/37 ,  C07C205/06

    CPC分类号： C07C255/58 ,  A61K31/136 ,  A61K31/277 ,  C07C205/06 ,  C07C205/37 ,  C07C211/56 ,  C07C217/92 ,  C07C229/58 ,  C07C233/65 ,  C07C255/57 ,  C07C255/59 ,  C07C323/36 ,  C07D213/643

    摘要： The invention relates to substituted diphenylamine compounds using as antitumor agents. The structure of the compounds is represented as the general formula (I): The groups are as defined as specification.The compound represented by formula (I) showed potent antitumor activity, especially to cure or alleviate the cancer causing by cancer cells of human tissue or organ. The preferred cancers are: colon cancer, liver cancer, lymph cancer, lung cancer, esophageal cancer, breast cancer, central nervous system cancer, melanoma, ovarian cancer, cervical cancer, renal cancer, leukemia, prostatic cancer, pancreatic cancer, bladder cancer, rectal cancer, osteosarcoma, nasopharynx cancer or stomach cancer.

    摘要翻译： 本发明涉及用作抗肿瘤剂的取代二苯胺化合物。 化合物的结构用通式（I）表示：这些基团如规定所定义。 由式（I）表示的化合物显示出有效的抗肿瘤活性，特别是用于治疗或减轻由人体组织或器官的癌细胞引起的癌症。 优选的癌症是：结肠癌，肝癌，淋巴癌，肺癌，食管癌，乳腺癌，中枢神经系统癌，黑素瘤，卵巢癌，子宫颈癌，肾癌，白血病，前列腺癌，胰腺癌，膀胱癌， 直肠癌，骨肉瘤，鼻咽癌或胃癌。

    HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF
    8.
    发明申请
    HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF 有权
    同型化合物及其用途

    公开(公告)号：US20150225378A1

    公开(公告)日：2015-08-13

    申请号：US14427795

    申请日：2013-10-24

    申请人： SINOCHEM CORPORATION ,  SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.

    发明人： Changling Liu ,  Aiying Guan ,  Jie Lan ,  Lizeng Wang ,  Bin Wang ,  Minna Zhu ,  Qin Sun ,  Weijing Ren ,  Cong Feng ,  Lanhui Ren ,  Baoshan Chai ,  Zhinian Li

    IPC分类号： C07D405/12 ,  A01N43/54

    CPC分类号： C07D405/12 ,  A01N43/54 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

    摘要： The invention discloses a homopiperony lamine compound which has a structural general formula I as follows as shown in the specification: wherein definitions of substituents in the formula are as shown in the specification. The compound shown as the general formula I has broad-spectrum bactericidal and insecticidal activity in the field of agriculture. The compound shown as the general formula I has a good prevention effect on various germs such as cucumber downy mildew, wheat powdery mildew, puccinia sorghi, rice blast and cucumber gray mold, and particularly, still has the good prevention and control effect on the cucumber downy mildew, the puccinia sorghi and the wheat powdery mildew at a lower dosage. At the same time, a part of compound has better insecticidal activity, and can be used for preventing and controlling various insect pests such as diamondback moths, myzus persicae, armyworms and tetranychus cinabarinus boisdu.

    摘要翻译： 本发明公开了具有如说明书中所示的结构通式I的高哌哆醇化合物：其中式中取代基的定义如说明书所示。 如通式I所示的化合物在农业领域具有广谱杀菌和杀虫活性。 如通式I所示的化合物对黄瓜霜霉病，小麦白粉病，红豆杉，稻瘟病和黄瓜灰霉病等各种细菌具有良好的预防作用，特别是对黄瓜具有良好的防治作用 霜霉病，小麦白菜和小白粉病，剂量较低。 同时，化合物的一部分具有更好的杀虫活性，可用于防治各种害虫如小菜蛾，桃蚜，粘虫和us藜。