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公开(公告)号：US09366667B2
公开(公告)日：2016-06-14
申请号：US13499867
申请日：2010-10-04
IPC分类号： G01N33/53 , A61K31/7088 , A61K39/15 , C07K14/005 , C07K16/10 , A61K39/12
CPC分类号： A61K39/15 , A61K31/7088 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C07K14/005 , C07K16/10 , C12N7/00 , C12N2720/12022 , C12N2720/12034 , C12N2720/12222 , C12N2720/12234 , G01N33/5308 , Y02A50/403
摘要： The invention is directed to a isolated a Piscine reovirus associated with HSMI in teleosts, and isolated nucleic acids sequences and peptides thereof. The invention also relates to diagnostic antibodies against antigens derived from Piscine reoviruses. In another aspect, the invention relates to iRNAs which target nucleic acid sequences of Piscine reoviruses. In another aspect, the invention is related to methods for detecting the presence or absence of Piscine reoviruses in an animal.
摘要翻译： 本发明涉及在硬骨鱼中与HSMI相关的分离的鱼类呼肠孤病毒，以及分离的核酸序列及其肽。 本发明还涉及针对源自Piscine呼肠孤病毒的抗原的诊断抗体。 另一方面，本发明涉及靶向鱼类呼肠病毒的核酸序列的iRNA。 另一方面，本发明涉及用于检测动物中鱼类呼吸道病毒存在或不存在的方法。
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公开(公告)号：US20130072542A1
公开(公告)日：2013-03-21
申请号：US13499867
申请日：2010-10-04
IPC分类号： G01N33/53 , A61K31/7088
CPC分类号： A61K39/15 , A61K31/7088 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C07K14/005 , C07K16/10 , C12N7/00 , C12N2720/12022 , C12N2720/12034 , C12N2720/12222 , C12N2720/12234 , G01N33/5308 , Y02A50/403
摘要： The invention is directed to a isolated a Piscine reovirus associated with HSMI in teleosts, and isolated nucleic acids sequences and peptides thereof. The invention also relates to diagnostic antibodies against antigens derived from Piscine re-oviruses. In another aspect, the invention relates to iRNAs which target nucleic acid sequences of Piscine reoviruses. In another aspect, the invention is related to methods for detecting the presence or absence of Piscine reoviruses in an animal.
摘要翻译： 本发明涉及在硬骨鱼中与HSMI相关的分离的鱼类呼肠孤病毒，以及分离的核酸序列及其肽。 本发明还涉及针对来自鱼类再次病毒的抗原的诊断抗体。 另一方面，本发明涉及靶向鱼类呼肠病毒的核酸序列的iRNA。 另一方面，本发明涉及用于检测动物中鱼类呼吸道病毒存在或不存在的方法。
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公开(公告)号：US20130058968A1
公开(公告)日：2013-03-07
申请号：US13499874
申请日：2010-10-04
CPC分类号： A61K39/15 , A61K31/7088 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/552 , A61K2039/70 , C07K14/005 , C07K16/10 , C12N7/00 , C12N2720/12022 , C12N2720/12034 , C12N2720/12222 , C12N2720/12234 , G01N33/5308 , Y02A50/403
摘要： The invention is directed to immunogenic compositions and methods for inducing an immune response against Piscine reoviruses in an animal. In another aspect, the invention relates to antibodies that bind Piscine reovirus poplypeptides. In yet another aspect, the invention relates to methods for preventing, or reducing PRV infection in an animal.
摘要翻译： 本发明涉及免疫原性组合物和用于诱导针对动物中的鱼类呼肠孤病毒的免疫应答的方法。 另一方面，本发明涉及结合Piscine呼肠孤病毒多肽的抗体。 在另一方面，本发明涉及用于预防或降低动物中PRV感染的方法。
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