Glycoprotein L and clycoprotein M from kaposi's sarcoma associated
herpesvirus, DNA encoding same and uses thereof
    1.
    发明授权
    Glycoprotein L and clycoprotein M from kaposi's sarcoma associated herpesvirus, DNA encoding same and uses thereof 失效
    来自卡波斯肉瘤相关疱疹病毒的糖蛋白L和clycoprotein M,编码该DNA的DNA及其用途

    公开(公告)号:US5853734A

    公开(公告)日:1998-12-29

    申请号:US747887

    申请日:1996-11-13

    摘要: This invention provides an isolated nucleic acid molecule which encodes KSHV glycoprotein L (gL). This invention provides an isolated nucleic acid molecule which encodes KSHV glycoprotein M (gM). This invention provides isolated gL and gM polypeptides. This invention provides antibodies specific to the polypeptides. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.

    摘要翻译: 本发明提供编码KSHV糖蛋白L(gL)的分离的核酸分子。 本发明提供编码KSHV糖蛋白M(gM)的分离的核酸分子。 本发明提供了分离的gL和gM多肽。 本发明提供对多肽特异的抗体。 还提供了反义和三重寡核苷酸分子。 本发明提供了一种用于卡波西肉瘤(KS)的疫苗。 本发明提供用KS接种,预防,诊断和治疗受试者的方法,并检测细胞中与卡波西肉瘤相关的DNA病毒的表达。

    Immediate early protein from Kaposi's sarcoma-associated herpesvirus,
DNA encoding same and uses thereof
    2.
    发明授权
    Immediate early protein from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof 失效
    来自卡波西肉瘤相关疱疹病毒的即时早期蛋白,编码相同的DNA及其用途

    公开(公告)号:US5948676A

    公开(公告)日:1999-09-07

    申请号:US728323

    申请日:1996-10-10

    摘要: This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) immediate early protein (IEP). This invention provides an isolated polypeptide molecule which encodes KSHV immediate early protein. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.

    摘要翻译: 本发明提供了编码卡波西肉瘤相关疱疹病毒(KSHV)立即早期蛋白质(IEP)的分离的核酸分子。 本发明提供编码KSHV立即早期蛋白质的分离的多肽分子。 本发明提供了针对该多肽的抗体。 还提供了反义和三重寡核苷酸分子。 本发明提供了一种用于卡波西肉瘤(KS)的疫苗。 本发明提供用KS接种,预防,诊断和治疗受试者的方法,并检测细胞中与卡波西肉瘤相关的DNA病毒的表达。

    Unique associated Kaposi's sarcoma virus sequences and uses thereof
    7.
    发明授权
    Unique associated Kaposi's sarcoma virus sequences and uses thereof 有权
    独特相关的卡波西氏肉瘤病毒序列及其用途

    公开(公告)号:US06348586B1

    公开(公告)日:2002-02-19

    申请号:US09230371

    申请日:1999-11-17

    IPC分类号: A61K39245

    摘要: This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) polypeptides. This invention provides an isolated polypeptide molecule of KSHV. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.

    摘要翻译: 本发明提供了编码卡波西肉瘤相关疱疹病毒(KSHV)多肽的分离的核酸分子。 本发明提供了KSHV的分离的多肽分子。 本发明提供了针对该多肽的抗体。 还提供了反义和三重寡核苷酸分子。 本发明提供了一种用于卡波西肉瘤(KS)的疫苗。 本发明提供用KS接种,预防,诊断和治疗受试者的方法,并检测细胞中与卡波西肉瘤相关的DNA病毒的表达。