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    SYSTEM AND METHOD FOR THE DELIVERY OF MEDICATIONS OR FLUIDS TO THE EYE
    1.
    发明申请
    SYSTEM AND METHOD FOR THE DELIVERY OF MEDICATIONS OR FLUIDS TO THE EYE 有权

    公开(公告)号：US20210361478A1

    公开(公告)日：2021-11-25

    申请号：US17394259

    申请日：2021-08-04

    Applicant: DAVID R. HARDTEN ,  RICHARD L. LINDSTROM

    Inventor： DAVID R. HARDTEN ,  RICHARD L. LINDSTROM

    IPC: A61F9/00

    Abstract: A method for delivering fluids, drugs, or medications to a patient's eye, and a system or apparatus for implementing the method, is disclosed. The system and method comprises the use of a corneal sponge to be deposited onto the cornea of the patient's eye while the patient's eyelids are maintained in open positions, and a scleral contact lens is disposed onto the sponge. The scleral lens has an irrigation fluid supply tube fluidically connected thereto for supplying a fluid, drug, or medication to the sponge which is saturated with the fluid, drug, or medication. Once the sponge and lens are inserted onto the corneal region of the eye, the patient's eyelids are closed thereby trapping and maintaining the sponge and lens upon the corneal region of the eye so as to permit the fluid, drug, or medication to be continuously supplied and applied to the corneal region of the eye.

    METHOD AND APPARATUS FOR PREVENTION AND TREATMENT OF ADULT GLAUCOMA
    5.
    发明申请
    METHOD AND APPARATUS FOR PREVENTION AND TREATMENT OF ADULT GLAUCOMA 审中-公开
    用于预防和治疗成年人的方法和装置

    公开(公告)号：US20080243247A1

    公开(公告)日：2008-10-02

    申请号：US12108712

    申请日：2008-04-24

    Applicant: Brooks J. Poley ,  Richard L. Lindstrom

    Inventor： Brooks J. Poley ,  Richard L. Lindstrom

    IPC: A61F2/16

    CPC classification number: A61F9/00781 ,  A61F2/1613 ,  A61F2/1694

    Abstract: An apparatus and method for reducing intraocular pressure in a patient's eye is provided. A deformable intraocular member having a relaxed state with a relaxed profile having a first width, a first energized state with a first profile having a second width, and a second energized state with a second profile having a third width is provided. The deformable intraocular member relaxed state width is greater than the width of a lens capsule which surrounds a lens of the patient's eye prior to cataract surgery. The second energized state width is greater than the patient's lens capsule width after cataract surgery and smaller than the width in the relaxed state. The deformable intraocular member in the second energized state is configured to urge deformation of the lens capsule to thereby promote opening of a trabecular meshwork and canal of Schlemm of the patient's eye to promote drainage of aqueous humor from an anterior chamber and reduce intraocular pressure in the patient's eye.

    Abstract translation: 提供了一种用于降低患者眼睛中眼内压的装置和方法。 提供具有松弛状态的松弛状态的可变形眼内部件，具有第一宽度的松弛轮廓，具有第二宽度的第一轮廓的第一带电状态和具有第三宽度的第二轮廓的第二带电状态。 可变形的眼内部件松弛状态宽度大于在白内障手术之前围绕患者眼睛的镜片的透镜胶囊的宽度。 白内障手术后第二次通电状态宽度大于患者的晶状体囊宽度，小于松弛状态下的宽度。 在第二通电状态下的可变形的眼内构件构造成促使晶状体囊的变形，从而促进患者眼睛的小梁网和Schlemm管的打开，以促进房水从前房排出并降低眼内压 病人的眼睛。

    Viscoelastic solution
    6.
    发明授权
    Viscoelastic solution 失效
    粘弹性溶液

    公开(公告)号：US5366964A

    公开(公告)日：1994-11-22

    申请号：US434305

    申请日：1989-11-13

    Applicant: Richard L. Lindstrom ,  Debra Skelnik

    Inventor： Richard L. Lindstrom ,  Debra Skelnik

    IPC: A61K38/18 ,  A61K31/715

    CPC classification number: A61K38/28 ,  A01N1/0226 ,  A61K38/1808 ,  Y10S514/912

    Abstract: A viscoelastic solution including a buffered solution, 0.01-10% chondroitin sulfate, 0.01-10% hydroxypropyl methylcellulose, and 0.01-10% sodium hyaluronate, pH adjusted to 6.0-8.0 at a osmolarity between 200-400 mOsmol/L. The buffered solution can be HEPES buffered minimal essential medium (MEM), phosphate buffered saline (PBS), or buffered balanced salt solution. A cell growth factor or cell growth supplement can also be included in the solution.

    Abstract translation: 包含缓冲溶液，0.01-10％硫酸软骨素，0.01-10％羟丙基甲基纤维素和0.01-10％透明质酸钠的粘弹性溶液，在200-400mOsmol / L的渗透压下pH调节至6.0-8.0。 缓冲溶液可以是HEPES缓冲的最小必需培养基（MEM），磷酸盐缓冲盐水（PBS）或缓冲平衡盐溶液。 细胞生长因子或细胞生长补充剂也可以包括在溶液中。

    Method for apparatus for a defined serumfree medical solution useful for corneal preservation
    7.
    发明授权
    Method for apparatus for a defined serumfree medical solution useful for corneal preservation 失效
    用于定义无血液药液的设备的方法，用于角膜保存

    公开(公告)号：US5104787A

    公开(公告)日：1992-04-14

    申请号：US487919

    申请日：1990-03-05

    Applicant: Richard L. Lindstrom ,  Debra Skelnik

    Inventor： Richard L. Lindstrom ,  Debra Skelnik

    IPC: A01N1/02 ,  A61F9/007 ,  A61K9/08

    CPC classification number: A01N1/0226

    Abstract: A defined serumfree medical solution for applications in Ophthalmology, that contains one or more cell nutrient supplements which maintains and enhances the preservation of eye tissues, including human corneal tissues at low temperatures (2.degree. C. to 15.degree. C.). This solution is composed of a defined aqueous nutrient and electrolyte solution, supplemented with a glycosaminoglycan(s), a deturgescent agent(s), an energy source(s), a buffer system(s), an antioxidant(s), membrane stabilizing components, antibiotic(s), ATP precursors and nutrient cell supplements.

    Abstract translation: 一种用于眼科应用的定义的无血液药物溶液，其含有一种或多种细胞营养补充剂，其在低温（2℃至15℃）下维持并增强眼组织的保存，包括人角膜组织。 该溶液由限定的水性营养物和电解质溶液组成，补充有糖胺聚糖，一种或多种防腐剂，能量源，缓冲系统，抗氧化剂，膜稳定剂 组分，抗生素，ATP前体和营养细胞补充剂。

    Additive for irrigation solution or surgical solution
    8.
    发明授权
    Additive for irrigation solution or surgical solution 失效
    灌洗溶液或手术溶液的添加剂

    公开(公告)号：US4886786A

    公开(公告)日：1989-12-12

    申请号：US151480

    申请日：1988-02-02

    Applicant: Richard L. Lindstrom ,  Debra L. Skelnik

    Inventor： Richard L. Lindstrom ,  Debra L. Skelnik

    IPC: A61K9/00

    CPC classification number: A61K9/0048

    Abstract: An additive for intraocular irrigation solution or surgical solution which provides the anterior chamber and posterior chamber of the eye with protection during surgical procedures that require irrigation. The additive for the solutions is composed of a balanced salt solution containing dextrose supplemented with chondroitin sulfate. Other chemical compositions can supplement the additive.

    Abstract translation: 用于眼内灌注溶液或手术溶液的添加剂，其在需要灌洗的外科手术过程中提供眼睛的前房和后房保护。 溶液的添加剂由含有补充硫酸软骨素的葡萄糖的平衡盐溶液组成。 其他化学成分可以补充添加剂。

    Intraocular lens
    9.
    发明授权
    Intraocular lens 失效
    人工晶状体

    公开(公告)号：US4781718A

    公开(公告)日：1988-11-01

    申请号：US106272

    申请日：1987-10-09

    Applicant: Richard L. Lindstrom

    Inventor： Richard L. Lindstrom

    IPC: A61F2/16

    CPC classification number: A61F2/16 ,  A61F2002/1681 ,  A61F2002/1686

    Abstract: Intraocular lens including loop haptic members each affixed at more than one point to a soft skirt of an optic or to a soft optic for torsional rigidity of the loop haptic member and for preventing loop rotation or pull out in an optic. The loop haptic members each include a main loop haptic member, and two branch members proceeding from the main loop haptic member to affix in securement holes in the edge or surface of an optic. The loops' securement end points include conically shaped end like members which engage within the soft portion of the IOL.

    Abstract translation: 包括环形触觉部件的眼内透镜，每个眼睛部件各自固定在光学元件的柔软裙部或柔性光学元件上，用于环形触觉部件的扭转刚度并用于防止光圈中的环转动或拉出。 环形触觉构件各自包括主环触觉构件和从主回路触觉构件进行的两个分支构件，以固定在光学元件的边缘或表面中的固定孔中。 环的固定端点包括接合在IOL的软部分内的锥形端部构件。

    Intraocular lens
    10.
    发明授权
    Intraocular lens 失效
    人工晶状体

    公开(公告)号：US4619656A

    公开(公告)日：1986-10-28

    申请号：US569610

    申请日：1984-01-10

    Applicant: Richard L. Lindstrom

    Inventor： Richard L. Lindstrom

    IPC: A61F2/16

    CPC classification number: A61F2/16 ,  A61F2/1664 ,  A61F2/161 ,  A61F2002/1681 ,  A61F2002/1683

    Abstract: Intraocular lens implant including an optic such as a plano-convex lens, a plurality of outwardly extending loops, and at least one key-hole affixed to one of the loops. In one embodiment, a plano-convex posterior chamber lens implant is provided with at least one key-hole loop in one of the two loops for turn-key insertion by locking a turn-key insertion instrument into a key-hole where the key-hole is at one end of one or both of the loops. The key locking into the key-hole provides for turn-key insertion of the loop with stable, secure, fixation, and control of the superior loop providing movement in all directions and all planes. This provides for rotation of the loop to rotate the lens implant posterior to the iris or into the capsular bag during a superior loop insertion technique.

    Abstract translation: 包括诸如平凸透镜的光学器件，多个向外延伸的环路以及固定到一个环路的至少一个键孔的眼内透镜植入物。 在一个实施例中，平凸后房透镜植入物在两个环之一中设置有至少一个键孔环，用于将钥匙插入仪器锁定到钥匙孔中， 孔位于一个或两个环的一端。 锁定在钥匙孔中的钥匙提供了环路的交钥匙插入，其具有稳定，牢固，固定和控制上环在所有方向和所有平面上的运动。 这提供了环路的旋转，以在优异的环路插入技术期间将透镜植入物旋转到虹膜后部或者进入囊袋。

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