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    Manufacturing Method of Kaempferol
    1.
    发明申请
    Manufacturing Method of Kaempferol 审中-公开
    山奈酚的制备方法

    公开(公告)号：US20080280335A1

    公开(公告)日：2008-11-13

    申请号：US11795343

    申请日：2005-05-30

    Applicant: Myeong Hoon Yeom ,  Jun-seong Park ,  Won-Seok Park ,  Kyungmi Joo ,  Ho Sik Rho ,  Duck Hee Kim ,  Ih Seop Jang ,  Ok-Sub Lee

    Inventor： Myeong Hoon Yeom ,  Jun-seong Park ,  Won-Seok Park ,  Kyungmi Joo ,  Ho Sik Rho ,  Duck Hee Kim ,  Ih Seop Jang ,  Ok-Sub Lee

    IPC: C12P17/06 ,  C07D311/04

    CPC classification number: C12P17/06

    Abstract: Disclosed is a kaempferol preparing method comprising isolating kaempferol from kaempferol glucosides using an acid, a base, an enzyme or a microbe producing the enzyme. More specifically, the method comprises obtaining a plant extract containing kaempferol glycosides from a plant using water or an organic solvent; and hydrolyzing the plant extract using an acid, a base, an enzyme or a microbe producing the enzyme to isolate kaempferol. The kaempferol glycosides comprise camelliaside A or camelliaside B. The plant extract is derived from a seed or leaf of green tea. When using the method of the invention, it is possible to mass-produce kaempferol, which is one of main physiological activating ingredients, from a plant, particularly a seed or leaf of green tea.

    Abstract translation: 公开了一种山奈酚的制备方法，其包括使用产生该酶的酸，碱，酶或微生物从山奈酚糖苷中分离山奈酚。 更具体地，该方法包括使用水或有机溶剂从植物获得含有山奈酚苷的植物提取物; 并使用产生该酶的酸，碱，酶或微生物水解植物提取物以分离山奈酚。 山奈酮糖苷含有山茶花A或山茶花B。植物提取物衍生自绿茶的种子或叶子。 当使用本发明的方法时，可以从植物，特别是绿茶的种子或叶中大量生产作为主要生理活性成分之一的山奈酚。

    Method for preparing 3-aminopropane phosphoric acid
    5.
    发明授权
    Method for preparing 3-aminopropane phosphoric acid 失效
    3-氨基丙烷磷酸的制备方法

    公开(公告)号：US5723645A

    公开(公告)日：1998-03-03

    申请号：US744352

    申请日：1996-11-04

    Applicant: Ok Sub Lee ,  Young Hun Byon ,  Bo Sub Lee ,  Jong Eon Hong ,  Jae Suk Ko ,  Yun Ki Cho ,  Ho Lee

    Inventor： Ok Sub Lee ,  Young Hun Byon ,  Bo Sub Lee ,  Jong Eon Hong ,  Jae Suk Ko ,  Yun Ki Cho ,  Ho Lee

    IPC: C07F9/09

    CPC classification number: C07F9/091

    Abstract: Disclosed herein is a method for preparing 3-aminopropane phosphoric acid represented by the formula (I), comprising the steps of (a) reacting 3-amino-1-propanoi with phosphorus oxychloride at a low temperature, and (b) hydrolyzing the product of the step (a) in the presence of an acidic catalyst, and a cosmetic composition containing 3-aminopropanic phosphoric acid or its salts as an active ingredient. ##STR1##

    Abstract translation: 本文公开了一种制备由式（I）表示的3-氨基丙烷磷酸的方法，包括以下步骤：（a）在低温下使3-氨基-1-丙酰与磷酰氯反应，和（b）水解产物 的步骤（a）在酸性催化剂的存在下进行，以及含有3-氨基丙酸或其盐作为有效成分的化妆品组合物。 （一）

    Sesamol Derivatives or Their Salts, The Process for Preparing the Same, and the Skin External Composition Containing the Same
    7.
    发明申请
    Sesamol Derivatives or Their Salts, The Process for Preparing the Same, and the Skin External Composition Containing the Same 有权
    芝麻素衍生物或其盐，其制备方法和含有其的皮肤外用组合物

    公开(公告)号：US20090131686A1

    公开(公告)日：2009-05-21

    申请号：US11921180

    申请日：2006-05-29

    Applicant: Jae Won You ,  Ho Sik Rho ,  Duc Hee Kim ,  Ih Seop Chang ,  Ok Sub Lee

    Inventor： Jae Won You ,  Ho Sik Rho ,  Duc Hee Kim ,  Ih Seop Chang ,  Ok Sub Lee

    IPC: C07F9/655 ,  A61Q19/08

    CPC classification number: A61K8/55 ,  A61K2800/522 ,  A61Q19/08 ,  C07F9/65517

    Abstract: The present invention relates to a sesamol derivative or its salt, and a skin external composition containing the same. More particularly, the invention relates to a sesamol derivative or its salt, which consists of sesamol and 3-aminopropane phosphoric acid, linked with each other by a phosphoric acid diester bond, and can be degraded into sesamol and 3-aminopropane phosphoric acid by enzymes present on the skin so as to simultaneously show the physiological activities of sesamol and 3-aminopropane phosphoric acid, as well as a preparation method thereof and a skin external composition containing the same.

    Abstract translation: 本发明涉及一种芝麻酚衍生物或其盐，以及包含其的皮肤外用组合物。 更具体地，本发明涉及由芝麻酚和3-氨基丙烷磷酸组成的芝麻酚衍生物或其盐，其通过磷酸二酯键彼此连接，并且可以通过酶降解成芝麻酚和3-氨基丙烷磷酸 存在于皮肤上，以同时显示西沙莫酚和3-氨基丙烷磷酸的生理活性，以及​​其制备方法和含有它们的皮肤外用组合物。

    Sesamol derivatives or their salts, the process for preparing the same, and the skin external composition containing the same
    10.
    发明授权
    Sesamol derivatives or their salts, the process for preparing the same, and the skin external composition containing the same 有权
    芝麻酚衍生物或其盐，其制备方法以及含有它们的皮肤外用组合物

    公开(公告)号：US07943599B2

    公开(公告)日：2011-05-17

    申请号：US11921180

    申请日：2006-05-29

    Applicant: Jae Won You ,  Ho Sik Rho ,  Duck Hee Kim ,  Ih Seop Chang ,  Ok Sub Lee

    Inventor： Jae Won You ,  Ho Sik Rho ,  Duck Hee Kim ,  Ih Seop Chang ,  Ok Sub Lee

    IPC: A61K31/66 ,  C07F9/12

    CPC classification number: A61K8/55 ,  A61K2800/522 ,  A61Q19/08 ,  C07F9/65517

    Abstract: The present invention relates to a sesamol derivative or its salt, and a skin external composition containing the same. More particularly, the invention relates to a sesamol derivative or its salt, which consists of sesamol and 3-aminopropane phosphoric acid, linked with each other by a phosphoric acid diester bond, and can be degraded into sesamol and 3-aminopropane phosphoric acid by enzymes present on the skin so as to simultaneously show the physiological activities of sesamol and 3-aminopropane phosphoric acid, as well as a preparation method thereof and a skin external composition containing the same.

    Abstract translation: 本发明涉及一种芝麻酚衍生物或其盐，以及包含其的皮肤外用组合物。 更具体地，本发明涉及由芝麻酚和3-氨基丙烷磷酸组成的芝麻酚衍生物或其盐，其通过磷酸二酯键彼此连接，并且可以通过酶降解成芝麻酚和3-氨基丙烷磷酸 存在于皮肤上，以同时显示西沙莫酚和3-氨基丙烷磷酸的生理活性，以及​​其制备方法和含有它们的皮肤外用组合物。

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