公开(公告)号：US07709786B2

公开(公告)日：2010-05-04

申请号：US11703381

申请日：2007-02-07

Applicant: Nikolai Konenkov ,  Donald J. Douglas ,  Xianzhen Zhao

Inventor： Nikolai Konenkov ,  Donald J. Douglas ,  Xianzhen Zhao

IPC: H01J49/04

CPC classification number: H01J49/4215 ,  H01J49/427

Abstract: A method of processing ions in a quadrupole rod set is provided, comprising a) establishing and maintaining a two-dimensional substantially quadrupole field having a quadrupole harmonic with amplitude A2 and a selected higher order harmonic with amplitude Am radially confining ions having Mathieu parameters a and q within a stability region defined in terms of the Mathieu parameters a and q; c) adding an auxiliary excitation field to transform the stability region into a plurality of smaller stability islands defined in terms of the Mathieu parameters a and q; and, d) adjusting the two-dimensional substantially quadrupole field to place ions within a selected range of mass-to-charge ratios within a selected stability island in the plurality of stability islands.

Abstract translation: 提供了一种处理四极杆组中的离子的方法，包括：a）建立和维持具有振幅A2的四极谐波的二维基本上四极场和具有幅度为Am的径向限制的具有Mathieu参数a的离子的选定的较高阶谐波，以及 q在由Mathieu参数a和q定义的稳定区域内; c）添加辅助激励场，以将稳定区域转换成由Mathieu参数a和q定义的多个较小的稳定岛; 以及d）调整二维基本四极场以将离子置于多个稳定岛内的所选稳定岛内的质荷比的选定范围内。

公开(公告)号：US07541579B2

公开(公告)日：2009-06-02

申请号：US11703478

申请日：2007-02-07

Applicant: Nikolai Konenkov ,  Frank Londry ,  Chuanfan Ding ,  Donald J. Douglas

Inventor： Nikolai Konenkov ,  Frank Londry ,  Chuanfan Ding ,  Donald J. Douglas

IPC: H01J49/42

CPC classification number: H01J49/4215

Abstract: A mass spectrometer and a method of operating and building same is provided in which a hexapole component is deliberately added to a substantially quadrupole field. This can result in unwanted octopole and dipole fields also being added to the substantially quadrupole field. Modifications to the mass spectrometer as well as ways of operating the mass spectrometer are provided for dealing with the unwanted octopole and dipole fields.

Abstract translation: 提供了质谱仪及其操作和制造方法，其中将六极组分故意添加到基本四极场。 这可能导致不需要的八极和偶极场也被添加到基本上四极场。 提供对质谱仪的修改以及操作质谱仪的方法用于处理不需要的八极和偶极场。

公开(公告)号：US20070295900A1

公开(公告)日：2007-12-27

申请号：US11703381

申请日：2007-02-07

Applicant: Nikolai Konenkov ,  Donald Douglas ,  Xianzhen Zhao

Inventor： Nikolai Konenkov ,  Donald Douglas ,  Xianzhen Zhao

IPC: B01D59/44

CPC classification number: H01J49/4215 ,  H01J49/427

Abstract: A method of processing ions in a quadrupole rod set us provided. The method comprises a) establishing and maintaining a two-dimensional substantially quadrupole field for processing the ions, the field having a quadrupole harmonic with amplitude A2 and a selected higher order harmonic with amplitude Am wherein m is an integer greater than 2, and the magnitude of Am is greater than 0.1% of the magnitude of A2; b)introducing the ions to the two-dimensional substantially quadrupole field and subjecting the ions to both the quadrupole harmonic and the higher order harmonic of the field to radially confine ions having Mathieu parameters a and q within a stability region defined in terms of the Mathieu parameters a and q; c) adding an auxiliary excitation field to transform the stability region into a plurality of smaller stability islands defined in terms of the Mathieu parameters a and q; and, d) adjusting the two-dimensional substantially quadrupole field to place ions within a selected range of mass-to-charge ratios within a selected stability island in the plurality of stability islands to impart stable trajectories to the selected ions within the selected range of mass-to-charge ratios for transmission through the rod set, and to impart unstable trajectories to unselected ions outside of the selected range of mass-to-charge ratios to filter out such ions.

Abstract translation: 我们提供了一种处理四极杆离子的方法。 该方法包括：a）建立和维持用于处理离子的二维基本四极场，该场具有振幅为A2的四极谐波和具有振幅Am的选定的较高次谐波，其中m为大于2的整数， 的Am大于A2的大小的0.1％; b）将离子引入二维基本上四极场，并使离子同时进行四极谐波和场的高次谐波，以将Mathieu参数a和q的离子径向地限制在根据Mathieu定义的稳定区域内 参数a和q; c）添加辅助激励场，以将稳定区域转换成由Mathieu参数a和q定义的多个较小的稳定岛; 以及d）调整二维基本四极场，以将离子置于选定的多个稳定岛中的稳定岛内的质荷比的选定范围内，以在所选择的离子的选定范围内给予稳定的轨迹 通过棒组传输的质荷比，并且将不稳定的轨迹赋予选定的质荷比范围外的未选择的离子，以过滤掉这些离子。

公开(公告)号：US20070272853A1

公开(公告)日：2007-11-29

申请号：US11703478

申请日：2007-02-07

Applicant: Nikolai Konenkov ,  Frank Londry ,  Chuanfan Ding ,  Donald Douglas

Inventor： Nikolai Konenkov ,  Frank Londry ,  Chuanfan Ding ,  Donald Douglas

IPC: H01J49/10

CPC classification number: H01J49/4215

Abstract: A mass spectrometer and a method of operating and building same is provided in which a hexapole component is deliberately added to a substantially quadrupole field. This can result in unwanted octopole and dipole fields also being added to the substantially quadrupole field. Modifications to the mass spectrometer as well as ways of operating the mass spectrometer are provided for dealing with the unwanted octopole and dipole fields.

Abstract translation: 提供了质谱仪及其操作和制造方法，其中将六极组分故意添加到基本四极场。 这可能导致不需要的八极和偶极场也被添加到基本上四极场。 提供对质谱仪的修改以及操作质谱仪的方法用于处理不需要的八极和偶极场。