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公开(公告)号：US07892740B2
公开(公告)日：2011-02-22
申请号：US12087964
申请日：2007-01-19
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , G01N33/57407 , G01N33/57484 , G01N2800/52
摘要： Disclosed is a set of genes differentially expressed in chemotherapy and radiation resistant tumors useful in predicting response to therapy and assessing risk of local-regional failure, survival and metastasis in cancer patients. Also disclosed are methods for characterizing tumors according to gene expression and kits for use in the methods of the invention.
摘要翻译： 公开了一组在化学疗法和耐辐射肿瘤中差异表达的基因，可用于预测治疗反应和评估癌症患者局部局部衰竭，存活和转移的风险。 还公开了根据基因表达表征肿瘤的方法和用于本发明方法的试剂盒。
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公开(公告)号：US20160367627A1
公开(公告)日：2016-12-22
申请号：US14901929
申请日：2014-06-24
CPC分类号： A61K38/177 , A61K31/506 , A61K45/06
摘要： Compositions, kits and methods for treating cancer in a subject in need thereof are disclosed involving one or more inhibitors of the JAK/STAT pathway which renders the cancer chemosensitive and/or radiosensitive.
摘要翻译： 公开了用于治疗有需要的受试者中的癌症的组合物，试剂盒和方法，涉及一种或多种使癌症化学敏感和/或放射敏感的JAK / STAT通路抑制剂。
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公开(公告)号：US09790504B2
公开(公告)日：2017-10-17
申请号：US14893690
申请日：2014-05-21
IPC分类号： C12N15/113 , C07H21/02 , A61K48/00 , A61K31/506 , A61K31/519 , A61K31/713 , A61K45/06 , C12Q1/68
CPC分类号： C12N15/1137 , A61K31/506 , A61K31/519 , A61K31/713 , A61K45/06 , C12N15/113 , C12N2310/14 , C12N2320/12 , C12N2320/30 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158
摘要： Panels, compositions, and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the cancer chemosensitive and/or radiosensitive.
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公开(公告)号：US20090011439A1
公开(公告)日：2009-01-08
申请号：US12087964
申请日：2007-01-19
IPC分类号： G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , G01N33/57407 , G01N33/57484 , G01N2800/52
摘要： Disclosed is a set of genes differentially expressed in chemotherapy and radiation resistant tumors useful in predicting response to therapy and assessing risk of local-regional failure, survival and metastasis in cancer patients. Also disclosed are methods for characterizing tumors according to gene expression and kits for use in the methods of the invention.
摘要翻译： 公开了一组在化学疗法和耐辐射肿瘤中差异表达的基因，可用于预测治疗反应和评估癌症患者局部局部衰竭，存活和转移的风险。 还公开了根据基因表达表征肿瘤的方法和用于本发明方法的试剂盒。
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公开(公告)号：US20060199210A1
公开(公告)日：2006-09-07
申请号：US11367602
申请日：2006-03-02
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/112
摘要： Disclosed are methods and kits for assessing risk of progression of Barrett's esophagus to adenocarcinoma.
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公开(公告)号：US20160222387A1
公开(公告)日：2016-08-04
申请号：US14893690
申请日：2014-05-21
IPC分类号： C12N15/113 , C12Q1/68 , A61K31/506 , A61K31/519 , A61K45/06 , A61K31/713
CPC分类号： C12N15/1137 , A61K31/506 , A61K31/519 , A61K31/713 , A61K45/06 , C12N15/113 , C12N2310/14 , C12N2320/12 , C12N2320/30 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158
摘要： Panels, compositions, and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the cancer chemosensitive and/or radiosensitive.
摘要翻译： 公开了涉及一种或多种抑制癌症化学敏感和/或辐射敏感的基因的治疗癌症的组合物，组合物和方法。
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公开(公告)号：US20110200998A1
公开(公告)日：2011-08-18
申请号：US13023331
申请日：2011-02-08
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , G01N33/57407 , G01N33/57484 , G01N2800/52
摘要： Disclosed is a set of genes differentially expressed in chemotherapy and radiation resistant tumors useful in predicting response to therapy and assessing risk of local-regional failure, survival and metastasis in cancer patients. Also disclosed are methods for characterizing tumors according to gene expression and kits for use in the methods of the invention.
摘要翻译： 公开了一组在化学疗法和耐辐射肿瘤中差异表达的基因，可用于预测治疗反应和评估癌症患者局部局部衰竭，存活和转移的风险。 还公开了根据基因表达表征肿瘤的方法和用于本发明方法的试剂盒。
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公开(公告)号：US07537894B2
公开(公告)日：2009-05-26
申请号：US11367602
申请日：2006-03-02
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/112
摘要： Disclosed are methods and kits for assessing risk of progression of Barrett's esophagus to adenocarcinoma.
摘要翻译： 公开了用于评估Barrett食管进展为腺癌的风险的方法和试剂盒。
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9.发明申请公开(公告)号：US20050048491A1
公开(公告)日：2005-03-03
申请号：US10492239
申请日：2002-10-09
IPC分类号： A61B20060101 , A61K48/00 , C12N5/00 , C12Q1/68 , C12Q1/6886 , G01N33/53 , G01N33/574
CPC分类号： G01N33/57484 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158
摘要： This invention provides methods and kits for use in selecting approaches to treating cancer, as well as methods for identifying genes that can be used in such methods and kits.
摘要翻译： 本发明提供了用于选择治疗癌症的方法的方法和试剂盒，以及用于鉴定可用于这些方法和试剂盒的基因的方法。
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