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公开(公告)号：US20240131129A1
公开(公告)日：2024-04-25
申请号：US18278985
申请日：2022-02-28
CPC分类号： A61K39/0008 , A61P25/28 , A61P37/06 , A61K2039/6037
摘要： Pharmaceutical composition for treating myasthenia gravis, comprising a carrier protein being SEQ ID NO:1 coupled to a plurality of a peptide epitope, the corresponding peptide epitopes and the method of synthesis of the conjugate.
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公开(公告)号：US20240226254A9
公开(公告)日：2024-07-11
申请号：US18278985
申请日：2022-02-28
CPC分类号： A61K39/0008 , A61P25/28 , A61P37/06 , A61K2039/6037
摘要： Pharmaceutical composition for treating myasthenia gravis, comprising a carrier protein being SEQ ID NO:1 coupled to a plurality of a peptide epitope, the corresponding peptide epitopes and the method of synthesis of the conjugate.
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公开(公告)号：US20240148863A1
公开(公告)日：2024-05-09
申请号：US18278978
申请日：2022-02-28
IPC分类号： A61K39/385 , C07K1/10
CPC分类号： A61K39/385 , C07K1/10 , A61K2039/627
摘要： Pharmaceutical composition comprising a conjugated peptide consisting of SEQ ID NO:1 to which several peptide epitopes are grafted covalently, kit comprising the elements for manufacturing this conjugated peptide, method of synthesis and use as vaccine.
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公开(公告)号：US08568657B2
公开(公告)日：2013-10-29
申请号：US12664398
申请日：2008-06-11
CPC分类号： B01F11/04 , B01F3/04262 , B01F2003/04319 , B01F2003/04361 , C12M23/00 , C12M23/14 , C12M37/04 , C12M41/00
摘要： A system providing a sterile connection between a sensor probe and a fluid processing apparatus (e.g., a bioreactor) includes a first probe receiving element mountable to the fluid processing apparatus and a second probe receiving element having a gas-permeable contaminant barrier material and coupleable to the first probe receiving element. A sensor probe may be mounted to the second probe receiving element, with the combination being sterilized with a sterilant gas such as steam. Following such sterilization, connection between the first and second probe receiving elements is made through matable sterile couplings, and the probe is insertable through the coupled receiving elements to a position in fluid contact with the interior of the fluid processing apparatus.
摘要翻译： 在传感器探针和流体处理装置（例如，生物反应器）之间提供无菌连接的系统包括可安装到流体处理装置的第一探针接收元件和具有气体可渗透的污染物阻挡材料的第二探针接收元件， 第一探头接收元件。 传感器探针可以安装到第二探针接收元件上，其中组合用诸如蒸汽的灭菌气体灭菌。 在这种消毒之后，第一和第二探针接收元件之间的连接是通过可配置的无菌联接件制成的，并且探头可通过联接的接收元件插入到与流体处理装置的内部流体接触的位置。
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公开(公告)号：US20100255526A1
公开(公告)日：2010-10-07
申请号：US12664398
申请日：2008-06-11
CPC分类号： B01F11/04 , B01F3/04262 , B01F2003/04319 , B01F2003/04361 , C12M23/00 , C12M23/14 , C12M37/04 , C12M41/00
摘要： A system providing a sterile connection between a sensor probe and a fluid processing apparatus (e.g., a bioreactor) includes a first probe receiving element mountable to the fluid processing apparatus and a second probe receiving element having a gas-permeable contaminant barrier material and coupleable to the first probe receiving element. A sensor probe may be mounted to the second probe receiving element, with the combination being sterilized with a sterilant gas such as steam. Following such sterilization, connection between the first and second probe receiving elements is made through matable sterile couplings, and the probe is insertable through the coupled receiving elements to a position in fluid contact with the interior of the fluid processing apparatus.
摘要翻译： 在传感器探针和流体处理装置（例如，生物反应器）之间提供无菌连接的系统包括可安装到流体处理装置的第一探针接收元件和具有气体可渗透的污染物阻挡材料的第二探针接收元件， 第一探头接收元件。 传感器探针可以安装到第二探针接收元件上，其中组合用诸如蒸汽的灭菌气体灭菌。 在这种消毒之后，第一和第二探针接收元件之间的连接是通过可配置的无菌联接件制成的，并且探头可通过联接的接收元件插入到与流体处理装置的内部流体接触的位置。
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