公开(公告)号：US20150176024A1

公开(公告)日：2015-06-25

申请号：US14411888

申请日：2013-06-28

申请人： NemGenix Pty Ltd

发明人： John Fosu-Nyarko ,  Michael George Kepler Jones

IPC分类号： C12N15/82 ,  C12N15/113

CPC分类号： C12N15/8285 ,  C12N15/113 ,  C12N15/1137 ,  C12N15/8218 ,  C12N15/8273 ,  C12N2310/14 ,  Y02A40/164

摘要： The invention relates to identifying and evaluating target coding and non-coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double-stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double-stranded RNA molecules, and the plant cells and plants obtained thereby.

摘要翻译： 本发明涉及通过抑制一种或多种生物学功能及其用途来鉴定和评价用于控制植物寄生线虫的靶编码和非编码序列。 本发明提供用于鉴定这种序列并控制植物寄生线虫种群的方法和组合物。 通过将本发明提供的一种或多种重组双链RNA分子送入线虫，通过抑制线虫基因表达可以获得疾病的减少。 本发明还涉及用于制备表达双链RNA分子的转基因植物以及由此获得的植物细胞和植物的方法。