摘要:
Methods of treating humans or animals having various conditions are disclosed which include administering a cyclosporine component. Among the conditions treated are dry mouth syndrome, verruciform xanthoma, achlorhydria, mucous cysts, oral submucous fibrosis, oral nevi, cancer of the oral mucosa, maloplakia of the genito-urinary tract, vulvovaginitis, helicobacter pylori infection, duodenal ulcers, peptic ulcers, conditions affecting the uterus and appendicitis.
摘要:
The present invention provides a method for the treatment of inflammatory diseases and/or conditions, e.g. allergic conjunctivitis, uveitis or phacoanaphylactic endophthalmitis in an eye of a mammal, said method comprising administering to said mammal in need of treatment a therapeutically effective amount of a novel cyclosporin A derivative selected from the group consisting of compounds represented by the formula: wherein R1 is S-Alk-R wherein Alk is an alkylene linkage, preferably a methylene or poly methylene linkage, or a polyalkenylene linkage, e.g. a C3 to C6 alkenylenyl linkage and R is a hydrogen or a unsubstituted or substituted hydrocarbyl group.
摘要:
Disclosed herein are novel analogs of cyclosporin, pharmaceutical compositions containing them, and methods for their use in the treatment of dry eye and other conditions.
摘要:
Methods of treating humans or animals having various conditions are disclosed which include administering a cyclosporine component. Among the conditions treated are dry mouth syndrome, verruciform xanthoma, achlorhydria, mucous cysts, oral submucous fibrosis, oral nevi, cancer of the oral mucosa, maloplakia of the genito-urinary tract, vulvovaginitis, helicobacter plylori infection, duodenal ulcers, peptic ulcers, conditions affecting the uterus and appendicitis.
摘要:
Irrigating solutions with thiol or disulfide containing compounds in physiologically acceptable salt solutions are described. The irrigating solutions are useful during surgery, particularly ophthalmic, neural, cardiovascular or otic surgery, to stabilize the affected tissue. Methods for their preparation and use are described.
摘要:
The present system uses measurement inputs which reveal fission product barrier functional characteristics for emergency event classification in nuclear generating stations. The process determines the functional status of barriers to fission product release under transient or emergency conditions. The first part of the present process specifies which key indicators within a nuclear plant provide data indicative of fission product barrier status, and develops a logic table or diagram relating specific key symptoms to barrier status such that a computer identifies the functional status of each fission product barrier. In the second part of the present process nuclear power plant operators utilize the computer to determine emergency event classification. The computer utilizes the present process, using the installed nuclear generating station instrumentation which indicates flow rates in fluid and air handling systems, pressures in pipes and vessels, temperatures in pipes and vessels, radiation levels and other indications of equipment status to determine whether the fission product barriers are functional at a given point in time according to the criteria established during the first part of the process. The implentation is an orderly process in which nuclear power plant operator uses the process as programmed on the computer to determine and correctly characterize the condition or status of each fission product barrier at any time. The process results in direct indication of the status of fission product barriers and of the categorization of the emergency event according to established classes of emergencies. If the computer is non-functional, the nuclear plant operator uses the process as presented in implementing procedures to determine the status of each fission product barrier and to determine the proper event clasification. The operator relies upon installed plant instrumentation to determine the functional status of the barriers according to the process.