公开(公告)号：US20240228590A9

公开(公告)日：2024-07-11

申请号：US18497735

申请日：2023-10-30

Applicant: MEMO THERAPEUTICS AG ,  UNIVERSITÄT BERN ,  UNIVERSITÄT ZÜRICH

Inventor： Marcel WEBER ,  Simone SCHMITT ,  Christoph ESSLINGER ,  Thomas SCHACHTNER ,  Uyen HUYNH-DO ,  Maurizio PROVENZANO

IPC: C07K16/08 ,  A61P31/20 ,  C12N15/63

CPC classification number: C07K16/084 ,  A61P31/20 ,  C12N15/63 ,  C07K2317/35 ,  C07K2317/565 ,  C07K2317/92

Abstract: Anti-BK virus antibody molecules or binding fragments thereof are disclosed. These Anti-BK virus antibody molecules or binding fragments can be used in the treatment or prevention of BK virus infection and/or BK virus associated disorder.

公开(公告)号：US20240132575A1

公开(公告)日：2024-04-25

申请号：US18497735

申请日：2023-10-29

Applicant: MEMO THERAPEUTICS AG ,  UNIVERSITÄT BERN ,  UNIVERSITÄT ZÜRICH

Inventor： Marcel WEBER ,  Simone SCHMITT ,  Christoph ESSLINGER ,  Thomas SCHACHTNER ,  Uyen HUYNH-DO ,  Maurizio PROVENZANO

IPC: C07K16/08 ,  A61P31/20 ,  C12N15/63

CPC classification number: C07K16/084 ,  A61P31/20 ,  C12N15/63 ,  C07K2317/35 ,  C07K2317/565 ,  C07K2317/92

Abstract: Anti-BK virus antibody molecules or binding fragments thereof are disclosed. These Anti-BK virus antibody molecules or binding fragments can be used in the treatment or prevention of BK virus infection and/or BK virus associated disorder.

公开(公告)号：US11312952B2

公开(公告)日：2022-04-26

申请号：US15118676

申请日：2015-02-13

Applicant: MEMO THERAPEUTICS AG

Inventor： Martin Held ,  Christoph Esslinger

IPC: C12N15/10 ,  C07K16/00 ,  C12Q1/6806 ,  G01N33/50 ,  G01N33/68 ,  C12Q1/686

Abstract: The present invention is related to a method for recovering two or more genes, or gene products, or cDNAs, encoding for an immunoreceptor having two or more subunits, which two or more genes, or gene products, are comprised in a given source cell. The invention is further related to a method of creating a library of expressor cells, in which library each cell is capable of expressing two or more genes, or gene products, encoding for the subunits of the immunoreceptor. The invention is further related to a method of screening a library of expressor cells as created according to the above method, for one cell that expresses an immunoreceptor that has specificity for a given target molecule.

公开(公告)号：US11919943B2

公开(公告)日：2024-03-05

申请号：US18049559

申请日：2022-10-25

Applicant: MEMO THERAPEUTICS AG ,  UNIVERSITÄT BERN ,  UNIVERSITÄT ZÜRICH

Inventor： Marcel Weber ,  Simone Schmitt ,  Christoph Esslinger ,  Thomas Schachtner ,  Uyen Huynh-Do ,  Maurizio Provenzano

IPC: C07K16/08 ,  A61P31/20 ,  C12N15/63

CPC classification number: C07K16/084 ,  A61P31/20 ,  C12N15/63 ,  C07K2317/35 ,  C07K2317/565 ,  C07K2317/92

Abstract: Anti-BK virus antibody molecules or binding fragments thereof are disclosed. These Anti-BK virus antibody molecules or binding fragments can be used in the treatment or prevention of BK virus infection and/or BK virus associated disorder.

公开(公告)号：US20230192816A1

公开(公告)日：2023-06-22

申请号：US18049559

申请日：2022-10-25

Applicant: MEMO THERAPEUTICS AG ,  UNIVERSITÄT BERN ,  UNIVERSITÄT ZÜRICH

Inventor： Marcel WEBER ,  Simone SCHMITT ,  Christoph ESSLINGER ,  Thomas SCHACHTNER ,  Uyen HUYNH-DO ,  Maurizio PROVENZANO

IPC: C07K16/08 ,  C12N15/63 ,  A61P31/20

CPC classification number: C07K16/084 ,  C12N15/63 ,  A61P31/20 ,  C07K2317/565 ,  C07K2317/35 ,  C07K2317/92

Abstract: Anti-BK virus antibody molecules or binding fragments thereof are disclosed. These Anti-BK virus antibody molecules or binding fragments can be used in the treatment or prevention of BK virus infection and/or BK virus associated disorder.

公开(公告)号：US20220127599A1

公开(公告)日：2022-04-28

申请号：US17520330

申请日：2021-11-05

Applicant: Memo Therapeutics AG

Inventor： Martin HELD ,  Christoph ESSLINGER

IPC: C12N15/10 ,  C07K16/00 ,  C12Q1/6806 ,  G01N33/50 ,  G01N33/68 ,  C12Q1/686

Abstract: The present invention is related to a method for recovering two or more genes, or gene products, or cDNAs, encoding for an immunoreceptor having two or more subunits, which two or more genes, or gene products, are comprised in a given source cell. The invention is further related to a method of creating a library of expressor cells, in which library each cell is capable of expressing two or more genes, or gene products, encoding for the subunits of the immunoreceptor. The invention is further related to a method of screening a library of expressor cells as created according to the above method, for one cell that expresses an immunoreceptor that has specificity for a given target molecule.

公开(公告)号：US11976276B2

公开(公告)日：2024-05-07

申请号：US17520330

申请日：2021-11-05

Applicant: Memo Therapeutics AG

Inventor： Martin Held ,  Christoph Esslinger

IPC: C12N15/10 ,  C07K16/00 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N33/50 ,  G01N33/68

CPC classification number: C12N15/1082 ,  C07K16/00 ,  C07K16/005 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N33/5023 ,  G01N33/5047 ,  G01N33/6845 ,  G01N33/6854 ,  C12Q1/686 ,  C12Q2521/107 ,  C12Q2563/149 ,  C12Q2563/159 ,  C12Q1/6806 ,  C12Q2521/107 ,  C12Q2563/149 ,  C12Q2563/159

Abstract: The present invention is related to a method for recovering two or more genes, or gene products, or cDNAs, encoding for an immunoreceptor having two or more subunits, which two or more genes, or gene products, are comprised in a given source cell. The invention is further related to a method of creating a library of expressor cells, in which library each cell is capable of expressing two or more genes, or gene products, encoding for the subunits of the immunoreceptor. The invention is further related to a method of screening a library of expressor cells as created according to the above method, for one cell that expresses an immunoreceptor that has specificity for a given target molecule.

公开(公告)号：US20230009582A1

公开(公告)日：2023-01-12

申请号：US17776980

申请日：2020-11-13

Applicant: MEMO THERAPEUTICS AG ,  UNIVERSITÄT BASEL

Inventor： Heinz LÄUBLI ,  Simone SCHMITT ,  Christoph ESSLINGER

IPC: C07K16/28 ,  C12N15/63 ,  A61P35/00

Abstract: Anti-Siglec-9 antibody molecules or binding fragments thereof are disclosed. These Anti-Siglec-9 antibody molecules or binding fragments can be used to treat cancer, acute or chronic hepatitis B.

公开(公告)号：US20170044523A1

公开(公告)日：2017-02-16

申请号：US15118676

申请日：2015-02-13

Applicant: MEMO THERAPEUTICS AG

Inventor： Martin HELD ,  Christoph ESSLINGER

IPC: C12N15/10

CPC classification number: C12N15/1082 ,  C07K16/00 ,  C07K16/005 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N33/5023 ,  G01N33/5047 ,  G01N33/6845 ,  G01N33/6854 ,  C12Q2521/107 ,  C12Q2563/149 ,  C12Q2563/159

Abstract: The present invention is related to a method for recovering two or more genes, or gene products, or cDNAs, encoding for an immunoreceptor having two or more subunits, which two or more genes, or gene products, are comprised in a given source cell. The invention is further related to a method of creating a library of expressor cells, in which library each cell is capable of expressing two or more genes, or gene products, encoding for the subunits of the immunoreceptor. The invention is further related to a method of screening a library of expressor cells as created according to the above method, for one cell that expresses an immunoreceptor that has specificity for a given target molecule.

Abstract translation: 本发明涉及一种用于回收编码具有两个或多个亚基的免疫受体的两个或多个基因或基因产物或cDNA的方法，所述两个或多个基因或基因产物包含在给定的源细胞中。 本发明还涉及创建表达细胞文库的方法，其中文库每个细胞能够表达编码免疫受体亚单位的两个或多个基因或基因产物。 本发明进一步涉及对于表达对给定靶分子具有特异性的免疫受体的一个细胞，筛选根据上述方法产生的表达细胞文库的方法。