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公开(公告)号：US12226140B2
公开(公告)日：2025-02-18
申请号：US17375215
申请日：2021-07-14
Applicant: Medtronic CryoCath LP
Inventor： Jean-Pierre Lalonde , Scott A. Hareland , Jay L. Kelley , Rachid Mahrouche , Wlodzimierz Sadzynski , Megan M. Schmidt , Bertin Simeon , Vladimir Tzonev
Abstract: A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains “soft” during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.
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2.发明授权公开(公告)号：US12004796B2
公开(公告)日：2024-06-11
申请号：US17335237
申请日：2021-06-01
Applicant: Medtronic CryoCath LP
Inventor： Boaz Avitall , Catherine R. Condie
CPC classification number: A61B18/02 , A61B2018/0022 , A61B2018/00404 , A61B2018/00577 , A61B2018/00684 , A61B2018/00821 , A61B2018/00875 , A61B2018/0212 , A61B2018/0268
Abstract: A cryoablation method, system, and device that allows for real-time and accurate assessment and monitoring of PV occlusion and lesion formation without the need for expensive imaging systems and without patient exposure to radiation. The system includes a cryoballoon catheter with a cryoballoon, a distal electrode, a proximal electrode, and a temperature sensor. Impedance measurements recorded by the electrodes may be used to predict ice formation, quality of pulmonary vein occlusion, and lesion formation.
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公开(公告)号：US11986231B2
公开(公告)日：2024-05-21
申请号：US17325307
申请日：2021-05-20
Applicant: Medtronic CryoCath LP
Inventor： Rahmani Sara , Lies Safar Remali
CPC classification number: A61B18/02 , A61B2017/00561 , A61B2017/00955 , A61B2018/0022 , A61B2018/0025 , A61B2018/00351 , A61B2018/00375 , A61B2018/00577 , A61B2018/00714 , A61B2018/00797 , A61B2018/00863 , A61B2018/00875 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
Abstract: A cryotreatment catheter for treating tissue. The catheter may include an outer elongate body, a balloon treatment element coupled to the distal portion of the elongate body with a plurality of balloon lobes radially arranged around the outer elongate body, an inner elongate body rotatably movable within the lumen of the outer elongate body, and a fluid delivery lumen located within the lumen of the outer elongate body and at least partially within the lumen of the inner elongate body. The fluid delivery lumen may be branched at a distal portion into a plurality of linear segments, each linear segment being in fluid communication with one of the plurality of balloon lobes. Each of the balloon lobes may be inflated independently of each other by the linear segments of the fluid delivery lumen.
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公开(公告)号：US11648044B2
公开(公告)日：2023-05-16
申请号：US16864184
申请日：2020-05-01
Applicant: Medtronic CryoCath LP
Inventor： Rachid Mahrouche , Eric Monger , Vladimir Tzonev
CPC classification number: A61B18/02 , F25B5/00 , F25B25/005 , F25B30/02 , F25J1/005 , F25B2309/021
Abstract: A system and kit for using a source of low-pressure refrigerant for a cryotherapy procedure and for subcooling a cryotherapy refrigerant. The system may generally include a fluid reservoir and a fluid flow path in thermal exchange with the fluid reservoir, the fluid flow path including a first thermal exchange device in thermal exchange with the fluid reservoir, a compressor in fluid communication with the first thermal exchange device, a condenser, a reversing valve located between the compressor and the condenser, a second thermal exchange device located between the reversing valve and the compressor, and an expansion valve located between the condenser and the thermal exchange device. The third thermal exchange device may be configured to be in fluid communication with the cryotherapy console and configured to place a secondary refrigerant within the first fluid flow path in thermal communication with a secondary refrigerant of the cryotherapy system.
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公开(公告)号：US11633225B2
公开(公告)日：2023-04-25
申请号：US16871165
申请日：2020-05-11
Applicant: Medtronic CryoCath LP
Inventor： Dan Wittenberger , Marwan Abboud , Ioana Deac
Abstract: The present invention provides a medical device that may include a catheter body having proximal and distal portions, a fluid injection lumen disposed within elongate body, and a guidewire lumen disposed within the elongate body. A tip portion defining a cavity in fluid communication with the fluid injection lumen may be coupled to the distal end of the guidewire lumen, and an expandable element may be coupled to the distal portion of the catheter body and to the tip portion, such that the expandable element is in fluid communication with the fluid injection lumen. A shaping element may at least partially surround the expandable element, where the shaping element is configurable in a first geometric configuration and a second geometric configuration.
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Patent Agency Ranking
公开(公告)号：US20230053149A1
公开(公告)日：2023-02-16
申请号：US17814405
申请日：2022-07-22
Applicant: Medtronic CryoCath LP
Inventor： Nicolas Coulombe , Rachid Mahrouche , Louis Jacob , Dan Wittenberger , Martin Lacharite , Jean-Pierre Lalonde
Abstract: A method of ablating tissue includes positioning a treatment device proximate to a target tissue area. The treatment device has an expandable treatment element. The expandable treatment element is inflated with a refrigerant during an inflation phase such that at least a portion of the expandable treatment element is in contact with the target tissue area. A first pressure measurement of the inflated expandable treatment element is recorded and compared to a predetermined pressure threshold. The refrigerant is circulated within the expandable treatment element during an ablation phase to reduce a temperature of the target tissue area to a temperature sufficient to cryoablate the target tissue area. A second pressure measurement of the expandable treatment element is recorded during the ablation phase and compared to the predetermined pressure threshold.
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公开(公告)号：US20220354561A1
公开(公告)日：2022-11-10
申请号：US17315592
申请日：2021-05-10
Applicant: Medtronic CryoCath LP
Inventor： Louis Jacob , Timothy A. Ebeling , Harold M. Dyalsingh , Trenton J. Rehberger , Craig W. Dorma
IPC: A61B18/02
Abstract: A system, method and leak signal discriminator for detection of a leak or mechanical breach in a catheter shaft in the presence of an electrical interferer are disclosed. According to one aspect, a leak signal discriminator having a leak detection circuit is configured to distinguish between a leak signal arising from a leak in a catheter and an interfering signal arising from an electrical interferer. The leak signal discriminator includes circuitry configured to receive from the leak detection circuit a response signal responsive to a test signal the test signal having component signals, each component signal being at a different frequency, and distinguish between a leak and an electrical interferer based at least in part on an evaluation of the response signal
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公开(公告)号：US20220338925A1
公开(公告)日：2022-10-27
申请号：US17811818
申请日：2022-07-11
Applicant: MEDTRONIC CRYOCATH LP
Inventor： Mark T. Stewart , Brian T. Howard , Steven J. Fraasch
Abstract: A device, system, and method for delivering energy to tissue. In particular, the present invention relates to a system and method for enhancing lesion formation without arrhythmogenic effects within relatively thick target tissues, such as the ventricles of the heart. In one embodiment, charge-neutral pulses and non-charge-neutral pulses may be delivered to induce the formation of electrolytic compounds that enhance cell death at the treatment site. Additionally or alternatively, tissue at the treatment site may be heated to sub-lethal temperature before ablating the tissue.
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公开(公告)号：US11471207B2
公开(公告)日：2022-10-18
申请号：US16788910
申请日：2020-02-12
Applicant: Medtronic CryoCath LP
Inventor： Nicolas Coulombe , Jean-Pierre Lalonde
Abstract: A method, system, and device for predicting lesion quality. Specifically, lesion quality may be predicted based on an assessment of pulmonary vein occlusion using injection of an impedance-modifying agent and evaluation of changes in impedance measurements recorded by an electrode located distal to an occlusion element of the treatment device used to inject the impedance-modifying agent. The quality of the occlusion may be rated based on the changes in impedance over time within the pulmonary vein. For example, the quality of the occlusion may be rated as being good, fair, or poor. This assessment may be quickly and easily communicated to an operator.
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公开(公告)号：US20220280217A1
公开(公告)日：2022-09-08
申请号：US17749704
申请日：2022-05-20
Applicant: Medtronic CryoCath LP
Inventor： Zhongping YANG , Linnea R. LENTZ , Rick D. MCVENES , Dan WITTENBERGER
IPC: A61B18/02
Abstract: A method for performing bronchial denervation, the method comprising an electromyography system having a cryoablation device with at least two recording electrodes. The electromyography system being configured to calculate a difference between a first electromyogram signal received from the first recording electrode and a second electromyogram signal received from the second recording electrode to generate a recorded electromyogram and compare the recorded electromyogram to a reference electromyogram.
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