-
公开(公告)号：US08580930B2
公开(公告)日：2013-11-12
申请号：US13589664
申请日：2012-08-20
Applicant: William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
Inventor： William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
-
公开(公告)号：US07943344B2
公开(公告)日：2011-05-17
申请号：US12632765
申请日：2009-12-07
Applicant: William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
Inventor： William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Abstract translation: 本发明提供结合并中和肝细胞生长因子（HGF），特别是人HGF的活性的结合蛋白家族。 结合蛋白可用作诊断和/或治疗剂。 关于它们的治疗活性，结合蛋白可用于治疗某些HGF应答性病症，例如某些HGF反应性肿瘤。
-
公开(公告)号：US07935502B2
公开(公告)日：2011-05-03
申请号：US12632758
申请日：2009-12-07
Applicant: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
Inventor： May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
-
公开(公告)号：US07649083B2
公开(公告)日：2010-01-19
申请号：US11757059
申请日：2007-06-01
Applicant: William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
Inventor： William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Abstract translation: 本发明提供结合并中和肝细胞生长因子（HGF），特别是人HGF的活性的结合蛋白家族。 结合蛋白可用作诊断和/或治疗剂。 关于它们的治疗活性，结合蛋白可用于治疗某些HGF应答性病症，例如某些HGF反应性肿瘤。
-
公开(公告)号：US08575318B2
公开(公告)日：2013-11-05
申请号：US13589652
申请日：2012-08-20
Applicant: May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
Inventor： May Han , S. Kirk Wright , William M. Winston, Jr. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Abstract translation: 本发明提供结合并中和肝细胞生长因子（HGF），特别是人HGF的活性的结合蛋白家族。 结合蛋白可用作诊断和/或治疗剂。 关于它们的治疗活性，结合蛋白可用于治疗某些HGF应答性病症，例如某些HGF反应性肿瘤。
-
Patent Agency Ranking
公开(公告)号：US20100173362A1
公开(公告)日：2010-07-08
申请号：US12632765
申请日：2009-12-07
Applicant: WILLIAM M. WINSTON, JR. , S. KIRK WRIGHT , MAY HAN , LYNE BREAULT , JIE LIN , BIJAN ETEMAD-GILBERTSON , CHRISTINE KNUEHL , JENO GYURIS , ARNOLD HORWITZ
Inventor： WILLIAM M. WINSTON, JR. , S. KIRK WRIGHT , MAY HAN , LYNE BREAULT , JIE LIN , BIJAN ETEMAD-GILBERTSON , CHRISTINE KNUEHL , JENO GYURIS , ARNOLD HORWITZ
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Abstract translation: 本发明提供结合并中和肝细胞生长因子（HGF），特别是人HGF的活性的结合蛋白家族。 结合蛋白可用作诊断和/或治疗剂。 关于它们的治疗活性，结合蛋白可用于治疗某些HGF应答性病症，例如某些HGF反应性肿瘤。
-
公开(公告)号：US20080108565A1
公开(公告)日：2008-05-08
申请号：US11757059
申请日：2007-06-01
Applicant: William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
Inventor： William M. Winston, Jr. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
-
公开(公告)号：US08603478B2
公开(公告)日：2013-12-10
申请号：US13177071
申请日：2011-07-06
Applicant: Kerry Whalen , Steve Bottega , Andrea Boudrow , Lyne Breault , Ting Chen , James Gifford , May Han , Jinwei Jiang , Lorena Lerner , Qing Liu , Kristan Meetze , Sylvie Vincent , Solly Weiler , William M. Winston, Jr. , Jeno Gyuris
Inventor： Kerry Whalen , Steve Bottega , Andrea Boudrow , Lyne Breault , Ting Chen , James Gifford , May Han , Jinwei Jiang , Lorena Lerner , Qing Liu , Kristan Meetze , Sylvie Vincent , Solly Weiler , William M. Winston, Jr. , Jeno Gyuris
IPC: A61K39/395
CPC classification number: C07K16/30 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: Monoclonal antibodies that bind and inhibit activation of human RON (Recepteur d' Origine Nantais) are disclosed. The antibodies can be used to treat certain forms of cancer that are associated with activation of RON.
Abstract translation: 公开了结合并抑制人RON（Recepteur d'Origine Nantais）活化的单克隆抗体。 抗体可用于治疗与RON活化相关的特定形式的癌症。
-
公开(公告)号：US20130203970A1
公开(公告)日：2013-08-08
申请号：US13589652
申请日：2012-08-20
Applicant: May Han , S. Kirk Wright , William M. Winston, JR. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
Inventor： May Han , S. Kirk Wright , William M. Winston, JR. , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris
IPC: C07K16/22
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
-
公开(公告)号：US20130203963A1
公开(公告)日：2013-08-08
申请号：US13589664
申请日：2012-08-20
Applicant: William M. Winston, JR. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
Inventor： William M. Winston, JR. , S. Kirk Wright , May Han , Lyne Breault , Jie Lin , Bijan Etemad-Gilbertson , Christine Knuehl , Jeno Gyuris , Arnold Horwitz
IPC: C07K16/22
CPC classification number: C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.
Abstract translation: 本发明提供结合并中和肝细胞生长因子（HGF），特别是人HGF的活性的结合蛋白家族。 结合蛋白可用作诊断和/或治疗剂。 关于它们的治疗活性，结合蛋白可用于治疗某些HGF应答性病症，例如某些HGF反应性肿瘤。
-
-
-
-
-
-
-
-
-
Search Results
20
records
(took 0.025 seconds)
