公开(公告)号：US09392143B1

公开(公告)日：2016-07-12

申请号：US12751130

申请日：2010-03-31

Applicant: Leslie D. Kohn ,  Manish Kumar Singh

Inventor： Leslie D. Kohn ,  Manish Kumar Singh

IPC: H04N1/60

CPC classification number: H04N1/6019

Abstract: An apparatus including a memory, a first circuit and a second circuit. The memory may be divided into eight banks. Each bank may store a portion of a three-dimensional (3D) color correction lookup table. The first circuit may be configured to address the memory in response to an index of an input point. The second circuit may be configured to arrange outputs of the eight banks for color interpolation.

Abstract translation: 一种包括存储器，第一电路和第二电路的装置。 存储器可以分为八个存储体。 每个银行可以存储三维（3D）颜色校正查找表的一部分。 第一电路可以被配置为响应于输入点的索引来寻址存储器。 第二电路可以被配置为布置八个组的输出用于颜色插值。

公开(公告)号：US20140079637A1

公开(公告)日：2014-03-20

申请号：US14006669

申请日：2012-03-22

Applicant: Warren Shawn Carbonell ,  Manish Kumar Aghi

Inventor： Warren Shawn Carbonell ,  Manish Kumar Aghi

IPC: A61K39/395 ,  A61K49/00

CPC classification number: A61K39/39558 ,  A61K49/00 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/545 ,  C07K16/22 ,  C07K16/2842 ,  C07K2317/73 ,  C12N2740/15043

Abstract: Described here are methods and compositions for treating tumors and metastases that improve anti-angiogenesis therapy. By inhibiting these mechanisms in a biological system with an anti-beta one integrin composition in combination with an anti-angiogenic composition, tumors and metastases may be deprived of an adequate blood supply, thereby resulting in tumor cell growth arrest and possibly regression, including tumor cell death. The present compositions comprise an anti-beta one integrin agent in combination with an anti-VEGF agent, in a pharmaceutical composition or compositions. Methods of treatment and of imaging are also described.

Abstract translation: 这里描述了用于治疗改善抗血管发生疗法的肿瘤和转移瘤的方法和组合物。 通过在具有抗β一整联蛋白组合物与抗血管生成组合物组合的生物系统中抑制这些机制，肿瘤和转移瘤可能被剥夺足够的血液供应，从而导致肿瘤细胞生长停滞并可能消退，包括肿瘤 细胞死亡。 在药物组合物或组合物中，本发明组合物包含抗β一整联蛋白剂与抗VEGF剂组合。 还描述了治疗和成像的方法。

公开(公告)号：US20140051785A1

公开(公告)日：2014-02-20

申请号：US13969939

申请日：2013-08-19

Applicant: Manish Kumar ,  Thomas A. Walz

Inventor： Manish Kumar ,  Thomas A. Walz

IPC: C08L89/00

CPC classification number: C08L89/00 ,  B01D67/0009 ,  B01D71/74 ,  B01D71/80 ,  B01D2323/12 ,  C08H1/00 ,  C08L53/00

Abstract: Embodiments of the invention provide methods for preparing high density membrane protein membranes by slow, controlled removal of detergent from mixtures of detergent, block copolymers and membrane protein mixtures. Membranes created by this method are also provided. The structure of these membranes may be varied by varying the amount of membrane protein.

Abstract translation: 本发明的实施方案提供了通过从洗涤剂，嵌段共聚物和膜蛋白质混合物的混合物缓慢控制去除洗涤剂来制备高密度膜蛋白质膜的方法。 还提供了通过该方法创建的膜。 这些膜的结构可以通过改变膜蛋白的量来改变。

公开(公告)号：US08655823B1

公开(公告)日：2014-02-18

申请号：US13069492

申请日：2011-03-23

Applicant: Manish Kumar

Inventor： Manish Kumar

IPC: G06F17/00 ,  G06N5/02

CPC classification number: G06N7/005 ,  G06F11/008 ,  G06F21/554 ,  H04L63/1425

Abstract: Improved techniques of identifying actions to take in response to events involve assigning, to each set of event parameter values which characterizes an event, a set of weight values, each weight value indicative of a probability of the event belonging to a cluster of events which follow a set of rules. To continue the previous example, an event management system may determine the probability of the first event belonging to the first cluster is 51% and that for the first event belonging to the second cluster is 49%, while the probability of the second event belonging to the first cluster is 49% and that for the second event belonging to the second cluster is 51%. In such a case, the event management system can be configured to respond to such similarly configured events in similar ways.

Abstract translation: 识别为应对事件而采取的动作的改进技术包括将表征事件的每组事件参数值分配给一组权重值，每个权重值表示事件属于随后的事件集合的概率 一套规则。 为了继续前面的示例，事件管理系统可以确定属于第一集群的第一事件的概率为51％，属于第二集群的第一事件的概率为49％，而第二事件属于第 第一个集群为49％，属于第二个集群的第二个集群为51％。 在这种情况下，可以将事件管理系统配置为以类似的方式响应于类似配置的事件。

公开(公告)号：US20140039904A1

公开(公告)日：2014-02-06

申请号：US13562467

申请日：2012-07-31

Applicant: Manish Kumar ,  Kainan Yin ,  Christine Matakovich ,  Mihai Petcov ,  Stephen Patches

Inventor： Manish Kumar ,  Kainan Yin ,  Christine Matakovich ,  Mihai Petcov ,  Stephen Patches

IPC: G06Q50/22

CPC classification number: G16H10/20 ,  G06Q10/10 ,  G06Q50/22

Abstract: Systems, methods, and other embodiments associated with data editing in a web-based interactive web response system are described. In one embodiment, a method includes receiving a request to perform an edit on a data field over a web-based protocol. The request is sent to an approval function that accesses stored authorization data to select an approval level associated with the data field. The approval function also determines an authorized approver mapped to the approval level to generate a notification over the web-based protocol. The notification is transmitted to at least one authorized approver over the web-based protocol. Approval to perform the edit is received from the at least one authorized approver over the web-based protocol.

Abstract translation: 描述了在基于web的交互式web响应系统中与数据编辑相关联的系统，方法和其他实施例。 在一个实施例中，一种方法包括通过基于web的协议接收对数据字段进行编辑的请求。 该请求被发送到访问存储的授权数据的批准功能，以选择与数据字段相关联的批准级别。 批准功能还确定映射到批准级别的授权审批者通过基于Web的协议生成通知。 该通知通过基于Web的协议传送给至少一个授权审批人。 通过基于Web的协议从至少一个授权审批者处收到执行编辑的批准。

公开(公告)号：US08516105B2

公开(公告)日：2013-08-20

申请号：US11627024

申请日：2007-01-25

Applicant: Jitendra Chawla ,  David Knight ,  Edward Wong ,  Manish Kumar ,  Shawn Farshchi ,  Eric Montoya

Inventor： Jitendra Chawla ,  David Knight ,  Edward Wong ,  Manish Kumar ,  Shawn Farshchi ,  Eric Montoya

IPC: G06F15/173

CPC classification number: H04L67/22 ,  G06Q10/103 ,  H04L12/1831 ,  H04N7/15 ,  H04N21/44218

Abstract: In one embodiment, the methods and apparatuses detect devices participating in a conference; monitor the devices for an attribute corresponding to an attention level of each of the devices; and determine whether each device is active based on the attention level.

Abstract translation: 在一个实施例中，所述方法和装置检测参与会议的设备; 监视与每个设备的关注度相对应的属性的设备; 并根据注意力水平确定每个设备是否处于活动状态。

公开(公告)号：US20130191474A1

公开(公告)日：2013-07-25

申请号：US13702575

申请日：2011-06-07

Applicant: Manish Kumar Goel ,  Roland John Turner

Inventor： Manish Kumar Goel ,  Roland John Turner

IPC: H04L12/58

CPC classification number: H04L51/12 ,  H04L63/0236

Abstract: The disclosure relates to ensuring wanted electronic messages are reliably delivered to recipients by distinguishing between wanted, authenticated messages and other messages. Notifications of messages that have been identified as spam are received (60) by a messaging recovery engine (30). The engine (30) via recovery module (44) determines (62) whether the email is in fact spam and if it is not spam generates (64) a notification to this effect, such as storing details in a database (34) or by generating instructions (48) to have the message delivered. The advantage is that after-the-fact analysis of security screened electronic messages can be performed. This makes it possible to use the method disclosed with existing messaging security systems with little or no modification to those existing systems. This in turn minimises barriers that would otherwise prevent adoption of methods for reducing false identification of a wanted message as an unwanted message allowing the messaging systems to benefit from improved message delivery.

Abstract translation: 本公开涉及通过区分想要的，已认证的消息和其他消息来确保所需的电子消息被可靠地传递给接收者。 通过消息传送恢复引擎（30）接收（60）已识别为垃圾邮件的消息的通知。 发动机（30）经由恢复模块（44）确定（62）电子邮件是否实际上是垃圾邮件，并且如果不是垃圾邮件，则生成（64）此类通知，例如将数据存储在数据库（34）中或通过 生成指令（48）以传送消息。 优点是可以执行安全屏蔽电子消息的事后分析。 这使得可以使用现有的消息传递安全系统公开的方法，而对这些现有系统几乎没有或没有修改。 这反过来最大限度地减少了否则将阻止采用减少所需消息的错误识别的方法作为不需要的消息的障碍，从而允许消息系统从改进的消息传递中受益。

公开(公告)号：US08447961B2

公开(公告)日：2013-05-21

申请号：US12708288

申请日：2010-02-18

Applicant: Anindya Saha ,  Manish Kumar ,  Hemant Mallapur ,  Santhosh Billava ,  Viji Rajangam

Inventor： Anindya Saha ,  Manish Kumar ,  Hemant Mallapur ,  Santhosh Billava ,  Viji Rajangam

IPC: G06F9/40

CPC classification number: G06F9/325 ,  G06F9/30065 ,  G06F9/381 ,  G06F9/3853

Abstract: A system to implement a zero overhead software pipelined (SFP) loop includes a Very Long Instruction Word (VLIW) processor having an N number of execution slots. The VLIW processor executes a plurality of instructions in parallel without any limitation of an instruction buffer size. A program memory receives a Program Memory address to fetch an instruction packet. The program memory is closely coupled with the instruction buffer size to implement the zero overhead software pipelined (SFP) loop. The size of the zero overhead software pipelined (SFP) loop can exceed the instruction buffer size. A CPU control register includes a block count and an iteration count. The block count is loaded into a block counter and counts the plurality of instructions executed in the SFP loop, and the iteration count is loaded into an iteration counter and counts a number of iterations of the SFP loop based on the block count.

Abstract translation: 实现零开销软件流水线（SFP）循环的系统包括具有N个执行时隙的超长指令字（VLIW）处理器。 VLIW处理器并行执行多个指令，而不受指令缓冲器大小的任何限制。 程序存储器接收程序存储器地址以获取指令包。 程序存储器与指令缓冲区大小紧密相连，以实现零开销软件流水线（SFP）循环。 零开销软件流水线（SFP）循环的大小可以超过指令缓冲区大小。 CPU控制寄存器包括块计数和迭代计数。 块计数被加载到块计数器中并对在SFP循环中执行的多个指令进行计数，并且将迭代计数加载到迭代计数器中，并且基于块计数对SFP循环的迭代次数进行计数。

公开(公告)号：US20110289168A1

公开(公告)日：2011-11-24

申请号：US13133921

申请日：2009-12-11

Applicant: Steven David Allam ,  Manish Kumar Goel

Inventor： Steven David Allam ,  Manish Kumar Goel

IPC: G06F15/16

CPC classification number: H04L51/24 ,  H04L51/30

Abstract: The disclosure relates to ensuring wanted electronic messages are reliably delivered to recipients by distinguishing between wanted, authenticated messages and other messages. Also, it provides for automatically compiling a datastore with senders of wanted inbound electronic communications. This is done by entering part entries into the datastore as messages are send outbound, and completing the entry as messages are sent inbound or with reference to an external datasource. The whitelist is automatically created and accurately populated and maintained without the need for any human involvement making it self training. This enables mass automation for whitelist generation and maintenance, and enables consistent, scalable deployment across any and all organisations to ensure accuracy in classification of wanted message senders. This disclosure also concerns using the datastore by identifying senders of inbound messages as senders of wanted emails according to a full or part match of their identification information.

Abstract translation: 本公开涉及通过区分想要的，已认证的消息和其他消息来确保所需的电子消息被可靠地传递给接收者。 此外，它还提供了自动编译数据存储区与发送者想要的入站电子通信。 这是通过在邮件发送出站时将部分条目输入到数据存储区中完成的，并且在邮件发送到内部或引用外部数据源时完成条目。 白名单自动创建并准确填充和维护，无需任何人员参与，使其自我培训。 这样可实现许多白名单生成和维护的大规模自动化，并可实现所有组织和所有组织的一致，可扩展的部署，以确保所需消息发送方的分类准确性。 本公开还涉及通过根据其标识信息的完整或部分匹配来将入站消息的发送者识别为所需电子邮件的发送者来使用数据存储。

公开(公告)号：US08030620B2

公开(公告)日：2011-10-04

申请号：US12435545

申请日：2009-05-05

Applicant: Vincent M. Donnelly ,  Demetre J. Economou ,  Paul Ruchhoeft ,  Lin Xu ,  Sri Charan Vemula ,  Manish Kumar Jain

Inventor： Vincent M. Donnelly ,  Demetre J. Economou ,  Paul Ruchhoeft ,  Lin Xu ,  Sri Charan Vemula ,  Manish Kumar Jain

IPC: H01J3/26 ,  G21K1/08

CPC classification number: B29D11/00365 ,  B82Y30/00

Abstract: A method is provided for creating a plurality of substantially uniform nano-scale features in a substantially parallel manner in which an array of micro-lenses is positioned on a surface of a substrate, where each micro-lens includes a hole such that the bottom of the hole corresponds to a portion of the surface of the substrate. A flux of charged particles, e.g., a beam of positive ions of a selected element, is applied to the micro-lens array. The flux of charged particles is focused at selected focal points on the substrate surface at the bottoms of the holes of the micro-lens array. The substrate is tilted at one or more selected angles to displace the locations of the focal points across the substrate surface. By depositing material or etching the surface of the substrate, several substantially uniform nanometer sized features may be rapidly created in each hole on the surface of the substrate in a substantially parallel manner.

Abstract translation: 提供了一种用于以基本上平行的方式产生多个基本均匀的纳米尺度特征的方法，其中微透镜阵列位于基底的表面上，其中每个微透镜包括孔，使得底部 孔对应于基板表面的一部分。 带电粒子的通量，例如所选元素的正离子束，被施加到微透镜阵列。 带电粒子的通量被聚焦在微透镜阵列的孔的底部的基底表面上的选定的焦点处。 衬底以一个或多个选定的角度倾斜，以便将焦点的位置移动穿过衬底表面。 通过沉积材料或蚀刻衬底的表面，可以以基本上平行的方式在衬底表面上的每个孔中快速产生几个基本均匀的纳米尺寸的特征。