CALCIUM PHOSPHATE GRANULES OF THE HYDROXYAPATITE TYPE, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS
    1.
    发明申请
    CALCIUM PHOSPHATE GRANULES OF THE HYDROXYAPATITE TYPE, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS 失效
    羟基磷酸钙的磷酸钙颗粒,其制备方法及其应用

    公开(公告)号:US20100150806A1

    公开(公告)日:2010-06-17

    申请号:US12636028

    申请日:2009-12-11

    CPC classification number: A61K9/2009 C01B25/327

    Abstract: The invention concerns calcium phosphates in granular form having an x-ray diffraction pattern characteristic of hydroxyapatite and good compressibility and flow properties in direct compression applications. The invention also concerns the method for preparing said granules characterized in that it comprises processing a suspension of brushite dicalcium phosphate having a certain particle-size distribution using a basic solution, and maintaining the pH at not less than 7.0 for a sufficient time interval to enable the transformation of the brushite calcium phosphate into hydroxyapatite calcium phosphate.

    Abstract translation: 本发明涉及具有羟基磷灰石的x射线衍射图谱特征的颗粒形式的磷酸钙,并且在直接压缩应用中具有良好的压缩性和流动性。 本发明还涉及制备所述颗粒的方法,其特征在于其包括使用碱性溶液处理具有一定粒度分布的磷酸钙二钙悬浮液,并将pH保持在不小于7.0的足够的时间间隔以使得能够 将钙磷酸钙转化为羟基磷灰石磷酸钙。

    HYDROXYAPATITE CALCIUM PHOSPHATES, THEIR METHOD OF PREPARATION AND THEIR APPLICATIONS
    2.
    发明申请
    HYDROXYAPATITE CALCIUM PHOSPHATES, THEIR METHOD OF PREPARATION AND THEIR APPLICATIONS 有权
    羟基磷酸钙,其制备方法及其应用

    公开(公告)号:US20090130444A1

    公开(公告)日:2009-05-21

    申请号:US12273875

    申请日:2008-11-19

    Abstract: The present invention is directed to calcium phosphates in granular form having an X-ray diffraction pattern characteristic of hydroxyapatite in which a portion of the anions of the crystal lattice are substituted with carbonate anions and which have good compressibility and flow properties in direct compression applications.The invention is also directed to the methods for preparing the calcium phosphate aforesaid granules characterized in that the methods include the processing of a brushite dicalcium phosphate solution having a specified particle size distribution using a solution of an alkaline earth carbonate for a sufficient period of time to allow the transformation of the brushite calcium phosphate into hydroxyapatite calcium phosphate.

    Abstract translation: 本发明涉及具有羟基磷灰石的X射线衍射图形特征的颗粒状磷酸钙,其中晶格的一部分阴离子被碳酸根阴离子取代,并且在直接压缩应用中具有良好的压缩性和流动性。 本发明还涉及上述制备磷酸钙前体颗粒的方法,其特征在于所述方法包括使用碱土金属碳酸盐溶液足够长的时间加工具有特定粒度分布的磷灰石磷酸二钙溶液, 允许将钙镁磷酸钙转化为羟基磷灰石磷酸钙。

    Hydroxapatite calcium phosphates, their method of preparation and their applications
    5.
    发明申请
    Hydroxapatite calcium phosphates, their method of preparation and their applications 失效
    羟磷灰石磷酸钙,其制备方法及其应用

    公开(公告)号:US20050271571A1

    公开(公告)日:2005-12-08

    申请号:US11125690

    申请日:2005-05-06

    Abstract: The present invention is directed to calcium phosphates in granular form having an X-ray diffraction pattern characteristic of hydroxyapatite in which a portion of the anions of the crystal lattice are substituted with carbonate anions and which have good compressibility and flow properties in direct compression applications. The invention is also directed to the methods for preparing the calcium phosphate aforesaid granules characterized in that the methods include the processing of a brushite dicalcium phosphate solution having a specified particle size distribution using a solution of an alkaline earth carbonate for a sufficient period of time to allow the transformation of the brushite calcium phosphate into hydroxyapatite calcium phosphate.

    Abstract translation: 本发明涉及具有羟基磷灰石的X射线衍射图形特征的颗粒状磷酸钙,其中晶格的一部分阴离子被碳酸根阴离子取代,并且在直接压缩应用中具有良好的压缩性和流动性。 本发明还涉及上述制备磷酸钙前体颗粒的方法,其特征在于所述方法包括使用碱土金属碳酸盐溶液足够长的时间加工具有特定粒度分布的磷灰石磷酸二钙溶液, 允许将钙镁磷酸钙转化为羟基磷灰石磷酸钙。

    Calcium phosphate granules of the hydroxyapatite type, their preparation process and their applications
    7.
    发明授权
    Calcium phosphate granules of the hydroxyapatite type, their preparation process and their applications 失效
    羟基磷灰石类型的磷酸钙颗粒,其制备方法及其应用

    公开(公告)号:US08414857B2

    公开(公告)日:2013-04-09

    申请号:US12636028

    申请日:2009-12-11

    CPC classification number: A61K9/2009 C01B25/327

    Abstract: The invention concerns calcium phosphates in granular form having an x-ray diffraction pattern characteristic of hydroxyapatite and good compressibility and flow properties in direct compression applications. The invention also concerns the method for preparing said granules characterized in that it comprises processing a suspension of brushite dicalcium phosphate having a certain particle-size distribution using a basic solution, and maintaining the pH at not less than 7.0 for a sufficient time interval to enable the transformation of the brushite calcium phosphate into hydroxyapatite calcium phosphate.

    Abstract translation: 本发明涉及具有羟基磷灰石的x射线衍射图谱特征的颗粒形式的磷酸钙,并且在直接压缩应用中具有良好的压缩性和流动性。 本发明还涉及制备所述颗粒的方法,其特征在于其包括使用碱性溶液处理具有一定粒度分布的磷酸钙二钙悬浮液,并将pH保持在不小于7.0的足够的时间间隔以使得能够 将钙磷酸钙转化为羟基磷灰石磷酸钙。

    Flame-Retardant System Based on Phosphorus Compounds and Flame-Retarded Polymer Composition
    9.
    发明申请
    Flame-Retardant System Based on Phosphorus Compounds and Flame-Retarded Polymer Composition 审中-公开
    基于磷化合物和阻燃聚合物组合物的阻燃体系

    公开(公告)号:US20080105857A1

    公开(公告)日:2008-05-08

    申请号:US10583170

    申请日:2004-12-17

    Abstract: The present invention relates to a flame-retardant system for polymers and to polymer-based flame-retarded compositions.It relates more particularly to a flame-retardant system comprising phosphorus-comprising compounds as flame-retardant agent. The invention provides a flame-retardant system, in particular for polymers and polymer-based compositions. This flame-retardant system comprises, as flame-retardant agent, at least one compound belonging to the family of the esters and salts of phosphoric, phosphinic and phosphonic acids and at least one other compound which stabilizes the flame-retardant agent.

    Abstract translation: 本发明涉及一种用于聚合物和基于聚合物的阻燃组合物的阻燃体系。 更具体地涉及包含含磷化合物作为阻燃剂的阻燃体系。 本发明提供阻燃体系,特别是聚合物和基于聚合物的组合物。 该阻燃剂体系包含至少一种属于磷酸,次膦酸和膦酸的酯和盐的化合物的至少一种化合物,以及使阻燃剂稳定的至少一种其它化合物。

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