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    WHOLE GENOME AMPLIFICATION METHOD AND APPLICATION THEREOF
    2.
    发明申请
    WHOLE GENOME AMPLIFICATION METHOD AND APPLICATION THEREOF 审中-公开
    全基因扩增方法及其应用

    公开(公告)号：US20150299753A1

    公开(公告)日：2015-10-22

    申请号：US14378935

    申请日：2012-03-30

    申请人： Kui WU ,  Hanjie WU ,  Yong HOU ,  Xun XU ,  Jun WANG

    发明人： Kui WU ,  Hanjie WU ,  Yong HOU ,  Xun XU ,  Jun WANG

    IPC分类号： C12P19/34 ,  C12Q1/68

    CPC分类号： C12P19/34 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2537/149

    摘要： Provided are a whole genome sample amplification method, a whole genome sequencing method, and a method for determining whether an abnormal state occurs in a whole genome, a whole genome sample amplification apparatus, a whole genome sequencing device, and a system for determining whether an abnormal state occurs in a whole genome. The whole genome sample amplification method comprises: subjecting a whole genome sample to a first amplification reaction, so as to obtain a first amplification product; and subjecting the first amplification product to a second amplification reaction, so as to obtain a second amplification product. The first amplification reaction is one of the PCR-based amplification reaction and the isothermal amplification reaction, and the second amplification reaction is the other of the PCR-based amplification reaction and the isothermal amplification reaction.

    摘要翻译： 提供了全基因组样品扩增方法，全基因组测序方法以及用于确定全基因组中是否发生异常状态的方法，全基因组样品扩增装置，全基因组测序装置和用于确定是否 异常状态发生在整个基因组中。 全基因组样品扩增方法包括：对全基因组样品进行第一次扩增反应，得到第一扩增产物; 并对第一扩增产物进行第二次扩增反应，得到第二扩增产物。 第一次扩增反应是基于PCR的扩增反应和等温扩增反应之一，第二次扩增反应是基于PCR的扩增反应和等温扩增反应中的另一个。

    Integrated Lens With Multiple Optical Structures and/or Surfaces, Optical Module and Transceiver Including the Same, and Methods of Making and Using the Same
    4.
    发明申请
    Integrated Lens With Multiple Optical Structures and/or Surfaces, Optical Module and Transceiver Including the Same, and Methods of Making and Using the Same 有权
    具有多个光学结构和/或表面的集成透镜，包括其的光学模块和收发器及其制造和使用方法

    公开(公告)号：US20160341903A1

    公开(公告)日：2016-11-24

    申请号：US14426326

    申请日：2015-02-12

    申请人： Xiaohui TANG ,  Qiang WANG ,  Kui WU ,  Yuanzhong XU

    发明人： Xiaohui TANG ,  Qiang WANG ,  Kui WU ,  Yuanzhong XU

    IPC分类号： G02B6/32 ,  G02B6/42

    CPC分类号： G02B6/32 ,  G02B6/4206 ,  G02B6/4214 ,  G02B6/4246 ,  G02B6/4255 ,  G02B6/4286 ,  G02B6/4292 ,  G02B6/4295

    摘要： An integrated lens with integrated functional optical surfaces for use in optical communication is disclosed. The integrated lens includes first and second cavities and a fiber adapter. The device also includes integrated first and second lenses. The first cavity houses one or more optical transmitting and/or receiving devices. The second cavity has a first optical surface and an optional second optical surface. The fiber adapter has the second lens. The integrated lens enables a small size, a light weight, high coupling and a high transmission efficiency, and can be produced by injection molding using a single mold. The integrated lens is applicable to optical signal coupling, fiber connections, optical modules, and optical or optoelectronic communication.

    摘要翻译： 公开了一种用于光通信的集成功能光学表面的集成透镜。 集成透镜包括第一和第二空腔以及光纤适配器。 该装置还包括集成的第一和第二透镜。 第一腔容纳一个或多个光发射和/或接收装置。 第二腔具有第一光学表面和可选的第二光学表面。 光纤适配器具有第二透镜。 集成透镜能够实现小尺寸，重量轻，高耦合和高传输效率，并且可以通过使用单个模具的注射成型来生产。 集成镜头适用于光信号耦合，光纤连接，光模块，光电或光电通信。

    INTEGRATED LENS WITH MULTIPLE OPTICAL STRUCTURES AND/OR SURFACES, OPTICAL MODULE AND TRANSCEIVER INCLUDING THE SAME, AND METHODS OF MAKING AND USING THE SAME
    5.
    发明申请
    INTEGRATED LENS WITH MULTIPLE OPTICAL STRUCTURES AND/OR SURFACES, OPTICAL MODULE AND TRANSCEIVER INCLUDING THE SAME, AND METHODS OF MAKING AND USING THE SAME 有权
    具有多个光学结构和/或表面的集成透镜，包括其的光学模块和收发器及其制造和使用方法

    公开(公告)号：US20160238794A1

    公开(公告)日：2016-08-18

    申请号：US14800062

    申请日：2015-07-15

    申请人： Xiaohui Tang ,  Qiang Wang ,  Kui Wu ,  Yuanzhong Xu

    发明人： Xiaohui Tang ,  Qiang Wang ,  Kui Wu ,  Yuanzhong Xu

    IPC分类号： G02B6/32 ,  H04B10/40 ,  G02B1/04 ,  G02B6/42 ,  G02B6/38 ,  H04B10/50 ,  H04B10/67

    CPC分类号： G02B6/32 ,  G02B1/041 ,  G02B6/3825 ,  G02B6/3865 ,  G02B6/4214 ,  G02B6/4292 ,  H04B10/40 ,  H04B10/501 ,  H04B10/67

    摘要： An integrated lens with integrated functional optical surfaces for use in optical communication is disclosed. The integrated lens includes first and second cavities and a fiber adapter. The device also includes integrated first and second lenses. The first cavity houses one or more optical transmitting and/or receiving devices. The second cavity has a first optical surface and an optional second optical surface. The fiber adapter has the second lens. The integrated lens enables a small size, a light weight, high coupling and a high transmission efficiency, and can be produced by injection molding using a single mold. The integrated lens is applicable to optical signal coupling, fiber connections, optical modules, and optical or optoelectronic communication.

    摘要翻译： 公开了一种用于光通信的集成功能光学表面的集成透镜。 集成透镜包括第一和第二空腔以及光纤适配器。 该装置还包括集成的第一和第二透镜。 第一腔容纳一个或多个光发射和/或接收装置。 第二腔具有第一光学表面和可选的第二光学表面。 光纤适配器具有第二透镜。 集成透镜能够实现小尺寸，重量轻，高耦合和高传输效率，并且可以通过使用单个模具的注射成型来生产。 集成镜头适用于光信号耦合，光纤连接，光模块，光电或光电通信。

    Method and device for genetic map construction, method and device for haplotype analysis
    6.
    发明申请
    Method and device for genetic map construction, method and device for haplotype analysis 有权
    用于遗传图谱构建的方法和装置，用于单倍型分析的方法和装置

    公开(公告)号：US20140194300A1

    公开(公告)日：2014-07-10

    申请号：US14240955

    申请日：2012-08-24

    申请人： Luting Song ,  Di Shao ,  Zequn Zheng ,  Zhijun Zheng ,  Kui Wu ,  Shuheng Liang ,  Ye Tao ,  Yong Hou

    发明人： Luting Song ,  Di Shao ,  Zequn Zheng ,  Zhijun Zheng ,  Kui Wu ,  Shuheng Liang ,  Ye Tao ,  Yong Hou

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6869 ,  C12Q1/6874 ,  C12Q1/6881 ,  C12Q2600/172 ,  G06F19/20 ,  G06F19/22

    摘要： Provided are the method and device for genetic map construction and the method and device for haplotype determination of a single cell. Wherein the method for genetic map construction includes: whole genome sequencing for at least a single cell from a same species, aligning the sequencing data to reference sequences respectively to determine genotypes of SNP sites, determining male parent a/female parent b typing results of SNP genotypes of a single cell based on the genotypes of SNP sites, dividing the chromosome of the species into linkage regions based on the male parent a/female parent b typing results of SNP genotypes, determining the variation ratio of a/b between two linkage regions to obtain recombination rate between every two continuous linkage regions, determining recombination map of a single cell according to the recombination rate, wherein the boundary site of a and b is the recombination site, determining the recombination rate of each recombination rate based on the recombination map to construct a genetic map of the species.

    摘要翻译： 提供遗传图谱构建的方法和装置以及单细胞单体型确定的方法和装置。 遗传图谱构建方法包括：对同一物种的至少一个细胞进行全基因组测序，分别将测序数据与参照序列进行比对，以确定SNP位点的基因型，确定SNP的雄性亲本a /雌性亲本B分型结果 基于SNP位点基因型的单细胞基因型，根据SNP基因型的雄性亲本a /雌性亲本B分型结果将该物种的染色体分为连锁区，确定两个连锁区之间a / b的变异比 以获得每两个连续连锁区域之间的重组率，根据复合率确定单个细胞的重组图谱，其中a和b的边界位点是重组位点，基于重组图确定每个重组速率的重组率 构建该物种的遗传图谱。

    Method and device for genetic map construction, method and device for haplotype analysis
    7.
    发明授权
    Method and device for genetic map construction, method and device for haplotype analysis 有权
    用于遗传图谱构建的方法和装置，用于单倍型分析的方法和装置

    公开(公告)号：US09309570B2

    公开(公告)日：2016-04-12

    申请号：US14240955

    申请日：2012-08-24

    申请人： Luting Song ,  Di Shao ,  Zequn Zheng ,  Zhijun Zheng ,  Kui Wu ,  Shuheng Liang ,  Ye Tao ,  Yong Hou

    发明人： Luting Song ,  Di Shao ,  Zequn Zheng ,  Zhijun Zheng ,  Kui Wu ,  Shuheng Liang ,  Ye Tao ,  Yong Hou

    IPC分类号： C12Q1/68 ,  C12M1/34 ,  G01N33/48 ,  G06F19/20 ,  G06F19/22

    CPC分类号： C12Q1/6869 ,  C12Q1/6874 ,  C12Q1/6881 ,  C12Q2600/172 ,  G06F19/20 ,  G06F19/22

    摘要： Provided are the method and device for genetic map construction and the method and device for haplotype determination of a single cell. Wherein the method for genetic map construction includes: whole genome sequencing for at least a single cell from a same species, aligning the sequencing data to reference sequences respectively to determine genotypes of SNP sites, determining male parent a/female parent b typing results of SNP genotypes of a single cell based on the genotypes of SNP sites, dividing the chromosome of the species into linkage regions based on the male parent a/female parent b typing results of SNP genotypes, determining the variation ratio of a/b between two linkage regions to obtain recombination rate between every two continuous linkage regions, determining recombination map of a single cell according to the recombination rate, wherein the boundary site of a and b is the recombination site, determining the recombination rate of each recombination rate based on the recombination map to construct a genetic map of the species.

    摘要翻译： 提供遗传图谱构建的方法和装置以及单细胞单体型确定的方法和装置。 遗传图谱构建方法包括：对同一物种的至少一个细胞进行全基因组测序，分别将测序数据与参照序列进行比对，以确定SNP位点的基因型，确定SNP的雄性亲本a /雌性亲本B分型结果 基于SNP位点基因型的单细胞基因型，根据SNP基因型的雄性亲本a /雌性亲本B分型结果将该物种的染色体分为连锁区，确定两个连锁区之间a / b的变异比 以获得每两个连续连锁区域之间的重组率，根据复合率确定单个细胞的重组图谱，其中a和b的边界位点是重组位点，基于重组图确定每个重组速率的重组率 构建该物种的遗传图谱。

    CO-LOCATION ELECTRICAL ARCHITECTURE
    9.
    发明申请
    CO-LOCATION ELECTRICAL ARCHITECTURE 有权
    合作电气结构

    公开(公告)号：US20150051749A1

    公开(公告)日：2015-02-19

    申请号：US14365165

    申请日：2011-12-16

    申请人： Martin A. Hancock ,  Matthew Stanlake ,  Peter C. Cowan ,  John C. Van Gorp ,  David Kidd ,  Hugh T. Lindsay ,  John Toffler ,  Catherine Gamroth ,  Kui Wu ,  Dimitri Marinakis

    发明人： Martin A. Hancock ,  Matthew Stanlake ,  Peter C. Cowan ,  John C. Van Gorp ,  David Kidd ,  Hugh T. Lindsay ,  John Toffler ,  Catherine Gamroth ,  Kui Wu ,  Dimitri Marinakis

    IPC分类号： G05F1/66 ,  G01R21/133

    CPC分类号： G05F1/66 ,  G01R21/1331 ,  G06Q50/06

    摘要： A system and method for managing an electrical distribution system in a facility is disclosed. In one aspect, the method may include receiving at a computer system from a monitoring system data related to actual energy use of components of the electrical distribution system, receiving at the computer system a request for a modification to the electrical distribution system, using the computer system, providing a revised electrical distribution system design based on the request and the data related to actual energy use using a system optimization function for the electrical distribution system, modifying the electrical distribution system in accordance with the revised electrical distribution system design to provide a modified electrical distribution system in the facility, and receiving at the computer system from the monitoring system data related to actual energy use of components of the modified electrical distribution system.

    摘要翻译： 公开了一种用于管理设施中的配电系统的系统和方法。 一方面，该方法可以包括在计算机系统处从监视系统接收与配电系统的组件的实际能量使用相关的数据，在计算机系统处接收使用计算机对配电系统进行修改的请求 系统，根据要求提供修订后的配电系统设计和与实际能源使用相关的数据，使用配电系统的系统优化功能，根据经修订的配电系统设计修改配电系统，以提供修改后的配电系统设计 设备中的配电系统，以及在计算机系统处从监控系统接收与修改的配电系统的部件的实际能量使用相关的数据。