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公开(公告)号:US20250060370A1
公开(公告)日:2025-02-20
申请号:US18820811
申请日:2024-08-30
Applicant: TSUTOMU TAKEUCHI , KEIKO YOSHIMOTO , KOWA COMPANY, LTD.
Inventor: Tsutomu Takeuchi , Keiko Yoshimoto
IPC: G01N33/68 , A61K39/00 , C07K14/705 , C07K16/24 , G01N33/564 , G01N33/74
Abstract: An antibody against a peptide having an amino acid sequence AVQGPEETVT QDC (expressed in single letter amino acid code) as represented by SEQ ID: NO1 corresponding to the 134- to 146-positions in human BAFF (B cell activating factor belonging to the TNF family) protein which is preferably a monoclonal antibody; a method of producing the above antibody; a medicinal composition containing the antibody; utilization of the antibody; and a method of screening an inhibitory effect or an activating effect on BAFF with the use of the antibody.
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公开(公告)号:US12186413B2
公开(公告)日:2025-01-07
申请号:US17441611
申请日:2020-03-27
Applicant: KOWA COMPANY, LTD.
Inventor: Misako Nakashima , Koichiro Iohara
IPC: A61K6/54 , A61K6/69 , A61K6/80 , A61K31/4375 , A61K31/4439 , A61K31/451 , A61K31/4725 , A61K38/18 , A61K38/19 , A61K38/48 , A61K45/06 , A61L27/22 , A61L27/36 , A61L27/54 , A61P1/02
Abstract: A non-cellular root canal filler comprises a tetrahydroisoquinoline compound or a pharmaceutically acceptable salt thereof, or a solvate of the compound or the salt, and a dental tissue regeneration promotion kit comprises a pretreatment agent comprising a serine protease, and the non-cellular root canal filler.
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公开(公告)号:US20240216272A1
公开(公告)日:2024-07-04
申请号:US18608109
申请日:2024-03-18
Applicant: KOWA COMPANY, LTD.
Inventor: Hiroshi ODA , Yuuki SUZUKI
IPC: A61K9/08 , A61J1/14 , A61K31/551 , A61P27/02 , A61P27/06 , B65D81/30 , C08K3/22 , C08K5/3475
CPC classification number: A61K9/08 , A61J1/1468 , A61K31/551 , A61P27/02 , A61P27/06 , B65D81/30 , C08K3/22 , C08K5/3475 , C08K2003/2241
Abstract: A technique is provided for improving the stability of a halogenated isoquinoline derivative with respect to light in an aqueous composition. A pharmaceutical preparation obtained by storing an aqueous composition comprising a compound represented by Formula (1):
wherein X represents a halogen atom,
or a salt thereof, or a solvate of the compound or the salt thereof, in a package that blocks a ray with a wavelength of 300 to 335 nm.-
公开(公告)号:US20240200768A1
公开(公告)日:2024-06-20
申请号:US18287210
申请日:2022-03-08
Applicant: KOWA COMPANY, LTD.
Inventor: Kentaro KANEKO , Takayuki FUJIOKA
IPC: F21V31/00 , F21V17/12 , F21V17/16 , F21Y105/18 , F21Y115/10
CPC classification number: F21V31/005 , F21V17/12 , F21V17/16 , F21Y2105/18 , F21Y2115/10
Abstract: Ring-type lighting device of the present invention comprises: a case member having an annular shape and comprising an inner wall portion and an outer wall portion, the inner wall portion defining a hollow portion at a center, the outer wall portion defining an opening portion that has an annular shape and surrounds the hollow portion; one or more LED members provided to face an opening of the opening portion; and a cover member that has an annular shape and is provided between the opening and the LED members to close the opening portion. Such a ring-type lighting device is easy to assemble and is reduced in size while having waterproof properties.
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公开(公告)号:US11969487B2
公开(公告)日:2024-04-30
申请号:US16651483
申请日:2018-09-21
Applicant: Kowa Company, Ltd.
Inventor: Misako Nakashima , Koichiro Iohara
IPC: A61K6/54 , A61K35/35 , A61K38/19 , A61K38/48 , A61K39/395 , A61K47/64 , A61L27/36 , A61L27/38 , A61L27/40 , A61P1/02
CPC classification number: A61K6/54 , A61K35/35 , A61K38/19 , A61K38/48 , A61K38/4826 , A61K39/395 , A61K47/642 , A61L27/36 , A61L27/3865 , A61L27/40 , A61P1/02
Abstract: A non-cellular dental tissue regeneration promoting kit is provided that makes effective dental tissue regeneration possible without transplantation of autologous or allogeneic stem cells or components derived from stem cells. The kit comprises: a pretreatment agent comprising a serine protease; and a non-cellular root canal filling material, the non-cellular root canal filling material comprising: a regeneration promoting compound including at least one of a CCR3 antagonist, a CCL11 neutralizing antibody, and an ALK5 inhibitor; and an extracellular matrix. The kit is preferably used for middle-aged or elderly individuals.
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公开(公告)号:US20240092953A1
公开(公告)日:2024-03-21
申请号:US18263730
申请日:2022-02-07
Applicant: KOWA COMPANY, LTD.
Inventor: Ryo KANAYA , Kenichi SUZUKI , Tsukasa CHIDA , Nobuhiro FUJIMAKI , Marina ECHIGO , Seiji MIURA
IPC: C08F220/28 , A61K9/51
CPC classification number: C08F220/286 , A61K9/5138 , C08F2800/20
Abstract: The present invention provides a novel copolymer available for a drug delivery technique. More particularly, a novel copolymer for a drug delivery carrier targeting a tumor is provided.
The present invention relates to a copolymer comprising structural units represented by the following formulas (A), (B), and (C):
wherein R1, R2, and R3 are the same or different and represent a hydrogen atom or a C1-3 alkyl group, R4 represents a C1-3 alkyl group, R5 represents a hydrogen atom, a C1-18 alkyl group, a 3- to 8-membered cycloalkyl group optionally having a substituent, an adamantyl group, a C6-18 aryl group optionally having a substituent, or a 5- to 10-membered heteroaryl group optionally having a substituent, X1, X2, and X3 are the same or different and represent an oxygen atom, a sulfur atom, or N—R7, R6 represents a hydrogen atom, a leaving group, or a linker, R7 represents a hydrogen atom or a C1-3 alkyl group, m represents an integer of 1 to 100, and n represents an integer of 0 to 3.-
公开(公告)号:USD1016875S1
公开(公告)日:2024-03-05
申请号:US29829352
申请日:2022-03-04
Applicant: KOWA COMPANY, LTD.
Designer: Kentaro Kaneko , Katsuyuki Masada
Abstract: FIG. 1 is a front perspective view of an industrial camera showing our new design;
FIG. 2 is a rear perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side elevational view thereof;
FIG. 6 is a right side elevational view thereof;
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.
The broken lines depict portions of the industrial camera in which the design is embodied that form no part of the claimed design.-
8.
公开(公告)号:US20240016131A1
公开(公告)日:2024-01-18
申请号:US18256568
申请日:2021-12-10
Inventor: Taiyo YOSHIOKA , Ryoko ICHIKI , Tsunenori KAMEDA , Takayuki MATSUDA , Atsushi ITO , Akimune ASANUMA
IPC: A01K67/033
CPC classification number: A01K67/033
Abstract: A simple and efficient breeding method for the bagworm moth is provided, as well as a device for performing the method. Also developed and provided is a method of easily collecting eggs from a bagworm moth, an egg collection device for bagworm moths composed of a tubular container. A bagworm moth breeding method and egg collection method performed using the device are also described.
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公开(公告)号:US11812157B2
公开(公告)日:2023-11-07
申请号:US17615085
申请日:2020-05-29
Applicant: Kowa Company, Ltd.
Inventor: Yutaka Mizukusa , Kunitoshi Shimizu
Abstract: In order to obtain an inspection image without blown-out highlights generated due to specular reflection or the like or blocked-up shadows generated at a position to which light hardly reaches, an image processing device includes a plurality of light sources that irradiates an object with light and a control circuit that controls light emission of the plurality of light sources, a camera that photographs the object, and a processor that controls switching of a light emission pattern of the plurality of light sources and controls photographing execution timing of the camera, controls the plurality of light sources to emit light with a plurality of light emission patterns, performs photographing at timings during at least two or more patterns among the plurality of light emission patterns to obtain a plurality of intermediate images, and generates one final image based on the plurality of obtained intermediate images.
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10.
公开(公告)号:US20230240274A1
公开(公告)日:2023-08-03
申请号:US18297360
申请日:2023-04-07
Inventor: Taiyo YOSHIOKA , Tsunenori KAMEDA , Takahiro KITAMURA , Akimune ASANUMA
Abstract: An object of the present invention is to develop: a method of efficiently producing a long bagworm silk thread containing no contaminant while preventing a change in the spinning direction and the runaway of the bagworm from a rail, and alleviating a burden on the bagworm; and an apparatus for implementing the thread-producing method. Provided is an apparatus for producing a bagworm silk thread, having a movable rail having a width smaller than the maximum width between the right and left legs of a bagworm and configured to move in the longitudinal direction and to be able to hold with the legs of the bagworm; and a fixator configured to fix a bagworm, wherein the fixator is placed at a position such that the fixed bagworm can hold the movable rail.
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