Anti-microbial proteins
    3.
    发明授权
    Anti-microbial proteins 失效
    抗微生物蛋白质

    公开(公告)号:US5607919A

    公开(公告)日:1997-03-04

    申请号:US543238

    申请日:1995-10-13

    摘要: Anti-microbial proteins isolated from sugar beet, wherein the anti-microbial proteins exclude chitinases and glucanases. Said proteins include a pure protein selected from those depicted in SEQ ID Nos 2, 5 and 8, or a functionally equivalent analogue thereof in which one or more amino acids have been added, substituted or removed without substantially reducing the protein's anti-microbial activity, or mixtures of such proteins or analogues. A synergistic anti-fungal effect is observed if at least one of the AX proteins is combined with a WIN protein. The invention also provides recombinant DNA comprising a sequence encoding a protein according to the invention, a vector comprising said DNA and transformed plants comprising said DNA. The invention further provides an anti-microbial composition containing one or more of the said proteins, and a process for combatting fungi or bacteria which comprises exposing them to said proteins or compositions.

    摘要翻译: 从甜菜中分离的抗微生物蛋白质,其中抗微生物蛋白质排除几丁质酶和葡聚糖酶。 所述蛋白质包括选自SEQ ID No.2,5和8中描述的那些的纯蛋白质或其功能上等同的类似物,其中一个或多个氨基酸已被添加,取代或除去而不显着降低蛋白质的抗微生物活性, 或这些蛋白质或类似物的混合物。 如果将至少一种AX蛋白与WIN蛋白结合,则观察到协同的抗真菌作用。 本发明还提供了包含编码本发明蛋白质的序列的重组DNA,包含所述DNA的载体和包含所述DNA的转化植物。 本发明还提供了含有一种或多种所述蛋白质的抗微生物组合物,以及用于对抗真菌或细菌的方法,其包括将其暴露于所述蛋白质或组合物。