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    Protection Against Sunburn And Skin Problems With Topical And Orally-Ingested Dosages Of Zeaxanthin
    2.
    发明申请
    Protection Against Sunburn And Skin Problems With Topical And Orally-Ingested Dosages Of Zeaxanthin 有权
    防止晒伤和皮肤问题与局部和口服摄入的玉米黄质的剂量

    公开(公告)号：US20120282204A1

    公开(公告)日：2012-11-08

    申请号：US13552461

    申请日：2012-07-18

    申请人： Dennis L. Gierhart ,  Joseph A. Fox

    发明人： Dennis L. Gierhart ,  Joseph A. Fox

    IPC分类号： A61K8/34 ,  A61K8/64 ,  A61Q19/04

    CPC分类号： A61K8/345 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/27 ,  A61K8/31 ,  A61K8/922 ,  A61K8/97 ,  A61K31/015 ,  A61K31/047 ,  A61K31/05 ,  A61K45/06 ,  A61K2800/81 ,  A61K2800/92 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/04 ,  A23V2200/308 ,  A23V2250/0632 ,  A23V2250/065 ,  A23V2250/0626 ,  A23V2250/0628 ,  A23V2250/063 ,  A23V2250/0638 ,  A23V2250/0648 ,  A23V2250/0654 ,  A23V2250/0604 ,  A23V2250/0606 ,  A23V2250/0608 ,  A23V2250/0616 ,  A23V2250/0618 ,  A23V2250/0622 ,  A23V2250/064 ,  A23V2250/0642 ,  A23V2250/0652 ,  A23V2250/0624 ,  A61K2300/00

    摘要： A carotenoid substance called zeaxanthin, when ingested orally at suitable dosages such as 30 to 100 mg/day for a span of 1 to 2 weeks, can provide effective protection against sunburns, and can give skin a darker tint that emulates a healthy suntan. In tests involving adults, it was found that zeaxanthin dosages of 30 to about 80 mg per day were sufficient to induce: (i) a mild but noticeable tinting, shading, or darkening of skin color, comparable to a mild suntan; (ii) a substantial increase in the person's ability to withstand elevated levels of sun or UV exposure without any subsequent pain or discomfort, and without the subsequent peeling and flaking that characterizes sunburns; and, (iii) an increased ability of reddened and sunburned skin to convert into intact skin that looks browned and healthily tanned. By reducing the amount of exposure to sunlight (or tanning lights) that are required to achieve a desired level of tanning, zeaxanthin can reduce the risks of skin cancer, premature aging or wrinkling, and similar skin problems. Since zeaxanthin also has retina-protecting properties and reduces the risk of a disease called macular degeneration, oral ingestion of these dosages of a zeaxanthin to enhance a tanned appearance and/or to protect against sun damage is believed to pose no health risks, and can offer several benefits due to the anti-oxidant and other activities of zeaxanthin.

    摘要翻译： 称为玉米黄质的类胡萝卜素物质以适当剂量例如30至100mg /天以1至2周的间隔口服摄取可提供有效保护，防止晒伤，并可使皮肤更暗，模拟健康的防晒霜。 在涉及成年人的测试中，发现每天30至约80mg的玉米黄质剂量足以诱导：（i）与轻度晒黑相当的轻度但明显的着色，阴影或变暗的肤色， （ii）大幅度增加人体抵抗阳光或紫外线暴露水平的能力，无任何后续的疼痛或不适，并且没有随后的晒伤和剥落，表现为晒伤; 和（iii）增加的红色和日晒皮肤的能力转化成完整的皮肤，看起来变褐和健康鞣制。 通过减少实现所需鞣制水平所需的阳光（或晒黑灯）的量，玉米黄质可以减少皮肤癌，过早老化或皱纹的风险，以及类似的皮肤问题。 由于玉米黄质还具有视网膜保护性质，并且降低称为黄斑变性的疾病的风险，所以认为这些剂量的玉米黄质的口服摄取可以增强鞣制外观和/或防止日晒损伤，这不构成健康风险，并且可以 由于玉米黄质的抗氧化和其他活性，提供了几个好处。

    Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
    4.
    发明授权
    Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin 有权
    通过口服高剂量玉米黄质防止晒伤和皮肤问题

    公开(公告)号：US08088363B2

    公开(公告)日：2012-01-03

    申请号：US10356134

    申请日：2003-02-01

    申请人： Dennis L. Gierhart ,  Joseph A. Fox

    发明人： Dennis L. Gierhart ,  Joseph A. Fox

    IPC分类号： A61K7/42 ,  A61K31/15

    CPC分类号： A61K8/345 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/27 ,  A61K8/31 ,  A61K8/922 ,  A61K8/97 ,  A61K31/015 ,  A61K31/047 ,  A61K31/05 ,  A61K45/06 ,  A61K2800/81 ,  A61K2800/92 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/04 ,  A23V2200/308 ,  A23V2250/0632 ,  A23V2250/065 ,  A23V2250/0626 ,  A23V2250/0628 ,  A23V2250/063 ,  A23V2250/0638 ,  A23V2250/0648 ,  A23V2250/0654 ,  A23V2250/0604 ,  A23V2250/0606 ,  A23V2250/0608 ,  A23V2250/0616 ,  A23V2250/0618 ,  A23V2250/0622 ,  A23V2250/064 ,  A23V2250/0642 ,  A23V2250/0652 ,  A23V2250/0624 ,  A61K2300/00

    摘要： A carotenoid substance called zeaxanthin, when ingested orally at suitable dosages such as 30 to 100 mg/day for a span of 1 to 2 weeks, can provide effective protection against sunburns, and can give skin a darker tint that emulates a healthy suntan. In tests involving adults, it was found that zeaxanthin dosages of 30 to about 80 mg per day were sufficient to induce: (i) a mild but noticeable tinting, shading, or darkening of skin color, comparable to a mild suntan; (ii) a substantial increase in the person's ability to withstand elevated levels of sun or UV exposure without any subsequent pain or discomfort, and without the subsequent peeling and flaking that characterizes sunburns; and, (iii) an increased ability of reddened and sunburned skin to convert into intact skin that looks browned and healthily tanned. By reducing the amount of exposure to sunlight (or tanning lights) that are required to achieve a desired level of tanning, zeaxanthin can reduce the risks of skin cancer, premature aging or wrinkling, and similar skin problems. Since zeaxanthin also has retina-protecting properties and reduces the risk of a disease called macular degeneration, oral ingestion of these dosages of a zeaxanthin to enhance a tanned appearance and/or to protect against sun damage is believed to pose no health risks, and can offer several benefits due to the anti-oxidant and other activities of zeaxanthin.

    摘要翻译： 称为玉米黄质的类胡萝卜素物质以适当剂量例如30至100mg /天以1至2周的间隔口服摄取可提供有效保护，防止晒伤，并可使皮肤更暗，模拟健康的防晒霜。 在涉及成年人的测试中，发现每天30至约80mg的玉米黄质剂量足以诱导：（i）与轻度晒黑相当的轻度但明显的着色，阴影或变暗的肤色， （ii）大幅度增加人体抵抗阳光或紫外线暴露水平的能力，无任何后续的疼痛或不适，并且没有随后的晒伤和剥落，表现为晒伤; 和（iii）增加的红色和日晒皮肤的能力转化成完整的皮肤，看起来变褐和健康鞣制。 通过减少实现所需鞣制水平所需的阳光（或晒黑灯）的量，玉米黄质可以减少皮肤癌，过早老化或皱纹的风险，以及类似的皮肤问题。 由于玉米黄质还具有视网膜保护性质，并且降低称为黄斑变性的疾病的风险，因此认为这些剂量的玉米黄质的口服摄取可以增强鞣制外观和/或防止日晒损伤，这不构成健康风险，并且可以 由于玉米黄质的抗氧化和其他活性，提供了几个好处。