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公开(公告)号：US20050090463A1
公开(公告)日：2005-04-28
申请号：US10861311
申请日：2004-06-04
Applicant: Christopher Roberts , Jesse Keicher
Inventor： Christopher Roberts , Jesse Keicher
IPC: A61K31/7076 , C07H19/00 , C07H19/04 , C07H19/20
CPC classification number: C07H19/00
Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
Abstract translation: 公开了用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染的化合物，组合物和方法。
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公开(公告)号：US20070167383A1
公开(公告)日：2007-07-19
申请号：US11559475
申请日：2006-11-14
Applicant: Christopher Roberts , Jesse Keicher , Natalia Dyatkina
Inventor： Christopher Roberts , Jesse Keicher , Natalia Dyatkina
IPC: A61K31/7076 , C07H19/20 , C07H19/22
CPC classification number: C07H19/14 , A61K31/7076
Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
Abstract translation: 公开了用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染的化合物，组合物和方法。
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公开(公告)号：US07094768B2
公开(公告)日：2006-08-22
申请号：US10821638
申请日：2004-04-08
Applicant: Christopher D. Roberts , Jesse Keicher , Natalia B. Dyatkina
Inventor： Christopher D. Roberts , Jesse Keicher , Natalia B. Dyatkina
CPC classification number: C07H19/00 , C07H19/167
Abstract: Disclosed are 6-hydroxyamino- or a 6-alkoxyamino-7-deazapurine-ribofuranose derivatives, salts, pharmaceutical compositions, and methods of use thereof for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
Abstract translation: 公开了6-羟基氨基或6-烷氧基氨基-7-脱氮嘌呤 - 呋喃核糖衍生物，盐，药物组合物及其用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染的方法。
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![Methods for preparing 7-(2'-substituted-beta-D-ribofuranosyl)-4-(NR2R3)-5-(substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine derivatives](/abs-image/US/2005/09/29/US20050215510A1/abs.jpg.150x150.jpg)
4.发明申请Methods for preparing 7-(2'-substituted-beta-D-ribofuranosyl)-4-(NR2R3)-5-(substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine derivatives 失效制备7-（2'-取代-β-D-呋喃核糖基）-4-（NR2R3）-5-（取代的乙炔-1-基） - 吡咯并[2,3-d]嘧啶衍生物的方法公开(公告)号：US20050215510A1
公开(公告)日：2005-09-29
申请号：US10970641
申请日：2004-10-20
Applicant: Christopher Roberts , Jesse Keicher , Natalia Dyatkina
Inventor： Christopher Roberts , Jesse Keicher , Natalia Dyatkina
IPC: C07H19/14 , C07H19/22 , A61K31/7076
CPC classification number: C07H19/14
Abstract: Disclosed are methods and intermediates for the preparation of 7-(2′-R1-substituted-β-D-ribofuranosyl)-4-amino-5-(optionally substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine compounds. These compounds are useful in treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
Abstract translation: 公开了制备7-（2'-R 1 - 取代-β-D-呋喃核糖基）-4-氨基-5-（任选取代的乙炔-1-基） - 吡咯并[2,3-d]嘧啶化合物。 这些化合物可用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染。
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公开(公告)号：US20050101550A1
公开(公告)日：2005-05-12
申请号：US10861219
申请日：2004-06-04
Applicant: Christopher Roberts , Jesse Keicher
Inventor： Christopher Roberts , Jesse Keicher
IPC: A61K31/7076 , C07H19/00 , C07H19/04 , C07H19/20
CPC classification number: C07H19/00
Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
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Patent Agency Ranking
公开(公告)号：US20060111311A1
公开(公告)日：2006-05-25
申请号：US11280984
申请日：2005-11-15
Applicant: Jesse Keicher , Christopher Roberts , Natalia Dyatkina
Inventor： Jesse Keicher , Christopher Roberts , Natalia Dyatkina
IPC: A61K31/7076 , C07H19/22
CPC classification number: A61K31/7076 , A61K38/21 , C07H19/14 , C07H19/22 , A61K2300/00
Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
Abstract translation: 公开了用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染的化合物，组合物和方法。
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公开(公告)号：US20060079468A1
公开(公告)日：2006-04-13
申请号：US10861090
申请日：2004-06-04
Applicant: Christopher Roberts , Jesse Keicher
Inventor： Christopher Roberts , Jesse Keicher
IPC: C07H19/00 , A61K31/7076
CPC classification number: C07H19/00
Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
Abstract translation: 公开了用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染的化合物，组合物和方法。
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公开(公告)号：US20050215511A1
公开(公告)日：2005-09-29
申请号：US10971477
申请日：2004-10-21
Applicant: Christopher Roberts , Jesse Keicher , Natalia Dyatkina
Inventor： Christopher Roberts , Jesse Keicher , Natalia Dyatkina
IPC: C07H19/14 , A61K31/7076 , C07H19/22
CPC classification number: C07H19/14 , A61K31/7076
Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
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公开(公告)号：US20050119200A1
公开(公告)日：2005-06-02
申请号：US10821638
申请日：2004-04-08
Applicant: Christopher Roberts , Jesse Keicher , Natalia Dyatkina
Inventor： Christopher Roberts , Jesse Keicher , Natalia Dyatkina
IPC: A61K31/7076 , C07H19/00 , C07H19/22
CPC classification number: C07H19/00 , C07H19/167
Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
Abstract translation: 公开的是用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染的化合物，组合物和方法。
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公开(公告)号：US20090036399A1
公开(公告)日：2009-02-05
申请号：US12206581
申请日：2008-09-08
Applicant: Christopher D. Roberts , Jesse Keicher , Natalia B. Dyatkina
Inventor： Christopher D. Roberts , Jesse Keicher , Natalia B. Dyatkina
IPC: A61K31/7064 , A61P31/12
CPC classification number: C07H19/00 , C07H19/167
Abstract: Disclosed are methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein W, W1, W2, Y, R1, Z, Y′ and R are as defined herein.
Abstract translation: 公开了用于治疗由黄病毒科家族病毒（例如丙型肝炎病毒）引起的病毒感染的方法。 这样的化合物由式I表示如下：其中W，W 1，W 2，Y，R 1，Z，Y'和R如本文所定义。
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