Process for the extraction of an active principle from yeast for the treatment of wrinkles and cosmetic compositions thereof
    4.
    发明授权
    Process for the extraction of an active principle from yeast for the treatment of wrinkles and cosmetic compositions thereof 有权
    从酵母提取活性成分用于治疗皱纹及其化妆品组合物的方法

    公开(公告)号:US06531132B1

    公开(公告)日:2003-03-11

    申请号:US09630611

    申请日:2000-08-02

    IPC分类号: A61K3500

    摘要: A process for extracting an active principle from yeast whereby the active principle is used to retard the degradation of the dermo-epidermal junction to improve the surface condition of the skin. The process includes forming a mixture of solubilized ground yeast in a basic medium, hydrolyzing the proteins of the mixture in a basic medium, agitating the mixture for 8 to 52 hours, filtering the mixture to separate the soluble and insoluble phases, washing with water so as to purify the active ingredient, concentrating and filtering to increase an active oligosaccharide fraction, and sterile filtering the active fraction. The active fraction is characterized by a quantity of dry material between 10 and 200 g/l, a quantity of total sugar between 10 and 100 g/l, a weight ratio of sugar/protein, and a pH between 4 and 10.

    摘要翻译: 从酵母提取活性成分的方法,由此使用活性成分来延缓皮肤 - 表皮连接处的降解以改善皮肤表面状况。 该方法包括在碱性介质中形成溶解的酵母的混合物,在碱性介质中水解混合物的蛋白质,搅拌混合物8至52小时,过滤混合物以分离可溶和不溶相,用水洗涤 为了纯化活性成分,浓缩和过滤以增加活性寡糖部分,并对活性级分进行无菌过滤。 活性级分的特征在于干物质的量为10至200g / l,总糖的量为10至100g / l,糖/蛋白质的重量比,以及4至10的pH。

    Process for the extraction of an active principle from teguments of apple, active principle obtained, and composition for counteracting the consequences of oxidative stress of the skin
    5.
    发明授权
    Process for the extraction of an active principle from teguments of apple, active principle obtained, and composition for counteracting the consequences of oxidative stress of the skin 失效
    苹果提取活性成分的方法,获得的活性成分以及抵消皮肤氧化应激后果的组合物

    公开(公告)号:US06506421B2

    公开(公告)日:2003-01-14

    申请号:US09848265

    申请日:2001-05-04

    IPC分类号: A61K3578

    CPC分类号: A61K8/97 A61Q19/08

    摘要: The present invention is a process for the extraction of an active principle for action against the consequences of oxidative stress, permitting countering cutaneous aging, characterized in that it comprises the following steps: reduction to fine powder of dried apple tegument, solubilization of this powder with at least 8% by volume of powder in an aqueous solution, conjoint enzymatic hydrolysis of the sugars and proteins, heating permitting total inactivation of the enzymes, and sterilizing filtration to retain the microorganisms, yeasts and molds as well as the total mesophilic flora. The invention also covers the associated compositions and a process for countering accelerated aging of the skin.

    摘要翻译: 本发明是提取用于抵抗氧化应激的后果的活性成分的方法,允许抗皮肤老化,其特征在于包括以下步骤:将干燥的苹果片剂还原成细粉末,将该粉末溶解于 在水溶液中至少8体积%的粉末,糖和蛋白质的酶水解,加热允许酶的完全失活,并进行过滤以保留微生物,酵母和霉菌以及总嗜温花粉。本发明 还涵盖相关组合物和用于抵抗皮肤加速老化的方法。