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1.发明授权Transgenic swine having HLA-D gene, swine cells thereof and xenografts therefrom 失效具有HLA-D基因的转基因猪，其猪细胞和异种移植物公开(公告)号：US06639122B1
公开(公告)日：2003-10-28
申请号：US09664846
申请日：2000-09-19
申请人： Ching-Fu Tu , Chun-Jean Lee , Jang-Ming Lee , Kimiyoshi Tsuji
发明人： Ching-Fu Tu , Chun-Jean Lee , Jang-Ming Lee , Kimiyoshi Tsuji
IPC分类号： A01K67027
CPC分类号： A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2227/108 , A01K2267/02 , A01K2267/025 , C07K14/70539 , C12N15/8509
摘要： The invention provides a transgenic swine having a transgene encoding a human HLA-DQ or HLA-DR protein, and the swine cells thereof. The invention also provides a graft derived from the transgenic swine, in particular a graft-organ or a graft-tissue, which is useful for grafting into a human recipient.
摘要翻译： 本发明提供了具有编码人HLA-DQ或HLA-DR蛋白的转基因的转基因猪及其猪细胞。 本发明还提供衍生自转基因猪的移植物，特别是移植物器官或移植物组织，其可用于移植到人接受者中。
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2.发明申请Biomarkers for predicting response of esophageal cancer patient to chemoradiotherapy 审中-公开用于预测食管癌患者对放化疗的反应的生物标志物公开(公告)号：US20130017961A1
公开(公告)日：2013-01-17
申请号：US13584610
申请日：2012-08-13
申请人： Pei-Chun Chen , Yen-Ching Chen , Liang-Chuan Lai , Mong-Hsun Tsai , Shin-Kuang Chen , Pei-Wen Yang , Jang-Ming Lee , Eric Y. Chuang , Chuhsing K. Hsiao
发明人： Pei-Chun Chen , Yen-Ching Chen , Liang-Chuan Lai , Mong-Hsun Tsai , Shin-Kuang Chen , Pei-Wen Yang , Jang-Ming Lee , Eric Y. Chuang , Chuhsing K. Hsiao
IPC分类号： C40B20/08
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/156
摘要： The present invention relates to novel genetic markers associated with response of a patient with esophageal cancer (ECa) to chemoradiation therapy, and particularly to methods and kits for predicting an ECa patient's response to chemoradiation therapy by genotyping of the markers.
摘要翻译： 本发明涉及与食管癌患者（ECa）对化学放疗疗法的反应相关的新型遗传标记，特别涉及用于通过标记基因分型来预测ECa患者对放化疗放疗反应的方法和试剂盒。
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3.发明授权Biomarkers for predicting response of esophageal cancer patient to chemoradiotherapy 有权用于预测食管癌患者对放化疗的反应的生物标志物公开(公告)号：US08268562B2
公开(公告)日：2012-09-18
申请号：US12582357
申请日：2009-10-20
申请人： Pei-Chun Chen , Yen-Ching Chen , Liang-Chuan Lai , Mong-Hsun Tsai , Shin-Kuang Chen , Pei-Wen Yang , Jang-Ming Lee , Eric Y. Chuang , Chuhsing K. Hsiao
发明人： Pei-Chun Chen , Yen-Ching Chen , Liang-Chuan Lai , Mong-Hsun Tsai , Shin-Kuang Chen , Pei-Wen Yang , Jang-Ming Lee , Eric Y. Chuang , Chuhsing K. Hsiao
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/156
摘要： The present invention relates to novel genetic markers associated with response of a patient with esophageal cancer (ECa) to chemoradiation therapy, and particularly to methods and kits for predicting an ECa patient's response to chemoradiation therapy by genotyping of the markers.
摘要翻译： 本发明涉及与食管癌患者（ECa）对化学放疗疗法的反应相关的新型遗传标记，特别涉及用于通过标记基因分型来预测ECa患者对放化疗放疗反应的方法和试剂盒。
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4.发明申请BIOMARKERS FOR PREDICTING RESPONSE OF ESOPHAGEAL CANCER PATIENT TO CHEMORADIOTHERAPY 有权预防食管癌患者对化疗的反应的生物标志物公开(公告)号：US20110091871A1
公开(公告)日：2011-04-21
申请号：US12582357
申请日：2009-10-20
申请人： Pei-Chun Chen , Yen-Ching Chen , Liang-Chuan Lai , Mong-Hsun Tsai , Shin-Kuang Chen , Pei-Wen Yang , Jang-Ming Lee , Eric Y. Chuang , Chuhsing K. Hsiao
发明人： Pei-Chun Chen , Yen-Ching Chen , Liang-Chuan Lai , Mong-Hsun Tsai , Shin-Kuang Chen , Pei-Wen Yang , Jang-Ming Lee , Eric Y. Chuang , Chuhsing K. Hsiao
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/156
摘要： The present invention relates to novel genetic markers associated with response of a patient with esophageal cancer (ECa) to chemoradiation therapy, and particularly to methods and kits for predicting an ECa patient's response to chemoradiation therapy by genotyping of the markers.
摘要翻译： 本发明涉及与食管癌患者（ECa）对化学放疗疗法的反应相关的新型遗传标记，特别涉及用于通过标记基因分型来预测ECa患者对放化疗放疗反应的方法和试剂盒。
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