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1.发明授权Systems and methods for non-destructively measuring calorie contents of food items 有权用于非破坏性测量食品卡路里含量的系统和方法公开(公告)号：US09297770B2
公开(公告)日：2016-03-29
申请号：US13193887
申请日：2011-07-29
申请人： Nilesh Tralshawala , John Frederick Graf , Jack Mathew Webster , Vasile Bogdan Neculaes , Sarah Lillian Katz
发明人： Nilesh Tralshawala , John Frederick Graf , Jack Mathew Webster , Vasile Bogdan Neculaes , Sarah Lillian Katz
摘要： A calorie estimating device for measuring a calorie content of a food item is provided. The device comprises a holder substrate, a transmitter antenna configured to transmit ultra-wide band (UWB) signals to at least a portion of the food item disposed on a side of the holder substrate, wherein the transmitter antenna comprises a planar antenna, a first receiver antenna configured to receive at least a portion of UWB signals reflected by the food item, wherein the first receiver antenna comprises a planar antenna, and a second receiver antenna configured to receive at least a portion of UWB signals propagated through the food item, wherein the second receiver antenna comprises a planar antenna.
摘要翻译： 提供了一种用于测量食物的卡路里含量的热量估计装置。 该装置包括保持器基板，发射器天线，被配置为将超宽带（UWB）信号传输到设置在保持器基板一侧的食品的至少一部分，其中发射器天线包括平面天线，第一 接收器天线，其被配置为接收所述食品反射的UWB信号的至少一部分，其中所述第一接收机天线包括平面天线，以及第二接收机天线，被配置为接收通过所述食品传播的UWB信号的至少一部分，其中 第二接收机天线包括平面天线。
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公开(公告)号：US08784774B2
公开(公告)日：2014-07-22
申请号：US13234210
申请日：2011-09-16
申请人： Jack Mathew Webster , Bruce Fletcher Johnson , Brian Duh-Lan Lee , Chittari Pabba , Michael James Rishel
发明人： Jack Mathew Webster , Bruce Fletcher Johnson , Brian Duh-Lan Lee , Chittari Pabba , Michael James Rishel
CPC分类号： A61K51/0406 , C07B59/001
摘要： Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection.
摘要翻译： 描述了包含能够通过胱氨酸/谷氨酸反向转运体引入细胞的标记底物的成像剂。 通过将标记的试剂通过胱氨酸/谷氨酸反转录酶引入细胞并随后检测，底物可用于成像或检测细胞中的氧化应激。
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3.发明申请SYSTEMS AND METHODS FOR NON-DESTRUCTIVELY MEASURING CALORIE CONTENTS OF FOOD ITEMS 有权用于非定向测量食品的卡路里内容的系统和方法公开(公告)号：US20130027060A1
公开(公告)日：2013-01-31
申请号：US13193887
申请日：2011-07-29
申请人： Nilesh Tralshawala , John Frederick Graf , Jack Mathew Webster , Vasile Bogdan Neculaes , Sarah Lillian Katz
发明人： Nilesh Tralshawala , John Frederick Graf , Jack Mathew Webster , Vasile Bogdan Neculaes , Sarah Lillian Katz
摘要： A calorie estimating device for measuring a calorie content of a food item is provided. The device comprises a holder substrate, a transmitter antenna configured to transmit ultra-wide band (UWB) signals to at least a portion of the food item disposed on a side of the holder substrate, wherein the transmitter antenna comprises a planar antenna, a first receiver antenna configured to receive at least a portion of UWB signals reflected by the food item, wherein the first receiver antenna comprises a planar antenna, and a second receiver antenna configured to receive at least a portion of UWB signals propagated through the food item, wherein the second receiver antenna comprises a planar antenna.
摘要翻译： 提供了一种用于测量食物的卡路里含量的热量估计装置。 该装置包括保持器基板，发射器天线，被配置为将超宽带（UWB）信号传输到设置在保持器基板一侧的食品的至少一部分，其中发射器天线包括平面天线，第一 接收器天线，其被配置为接收由所述食品反射的UWB信号的至少一部分，其中所述第一接收机天线包括平面天线，以及第二接收机天线，被配置为接收通过所述食品传播的UWB信号的至少一部分，其中 第二接收机天线包括平面天线。
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公开(公告)号：US08318456B2
公开(公告)日：2012-11-27
申请号：US13479009
申请日：2012-05-23
IPC分类号： C07K14/435 , C07H21/02 , C12P21/06
摘要： Provided herein are isolated polypeptides derived from the staphylococcal protein A protein B domain comprising a pair of anti-parallel alpha helices that are capable of binding a target. Also provided are nucleic acid sequences encoding such two helix binders, vectors containing the nucleic acid sequences encoding for two helix binders, and host cells transformed with vectors containing the nucleic acid sequences encoding for the two-helix binders. Also provided are methods of using the two helix binders.
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公开(公告)号：US20120253006A1
公开(公告)日：2012-10-04
申请号：US13479009
申请日：2012-05-23
IPC分类号： C07K14/00
摘要： Provided herein are isolated polypeptides derived from the staphylococcal protein A protein B domain comprising a pair of anti-parallel alpha helices that are capable of binding a target. Also provided are nucleic acid sequences encoding such two helix binders, vectors containing the nucleic acid sequences encoding for two helix binders, and host cells transformed with vectors containing the nucleic acid sequences encoding for the two-helix binders. Also provided are methods of using the two helix binders.
摘要翻译： 本文提供了衍生自葡萄球菌蛋白A蛋白B结构域的分离的多肽，其包含能够结合靶标的一对反平行α螺旋。 还提供了编码这种两个螺旋粘合剂的核酸序列，含有编码两个螺旋结合物的核酸序列的载体，以及用含有编码双螺旋结合物的核酸序列的载体转化的宿主细胞。 还提供了使用两种螺旋粘合剂的方法。
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6.发明申请公开(公告)号：US20120053426A1
公开(公告)日：2012-03-01
申请号：US12873067
申请日：2010-08-31
摘要： A system includes an estimating unit to non-destructively estimate a fat content and a water content of a food sample. The system further includes a processing unit operatively coupled to the estimating unit to determine a calorie content based solely on the fat content and the water content of the food sample.
摘要翻译： 一种系统包括估计单元，以非破坏性地估计食物样品的脂肪含量和含水量。 该系统还包括可操作地耦合到估计单元的处理单元，以仅基于食物样品的脂肪含量和水含量来确定卡路里含量。
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公开(公告)号：US20100035361A1
公开(公告)日：2010-02-11
申请号：US12337941
申请日：2008-12-18
IPC分类号： G01N33/566 , C07K14/00 , C07K5/10
摘要： An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein. Introduction of an engineered disulfide bridge between two natural or un-natural amino acids in the polypeptide is provided here. Also provided are methods of using the two-helix binders.
摘要翻译： 衍生自葡萄球菌蛋白A的B结构域的分离的多肽Z结构域，其包含能够结合靶的一对反平行α螺旋。 在这里提供了多肽中两个天然或非天然氨基酸之间的工程化二硫桥的引入。 还提供了使用双螺旋粘合剂的方法。
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公开(公告)号：US20090325313A1
公开(公告)日：2009-12-31
申请号：US12337945
申请日：2008-12-18
IPC分类号： G01N33/566 , C07K14/00
CPC分类号： C07K14/31
摘要： An isolated polypeptide, Z domain, derived from B domain of Staphylococcal protein A, comprising a pair of anti-parallel alpha helices that are capable of binding a target, is provided herein. Introduction of an un-natural amino acid in the polypeptide is provided here. Also provided are methods of using the two-helix binders.
摘要翻译： 衍生自葡萄球菌蛋白A的B结构域的分离的多肽Z结构域，其包含能够结合靶的一对反平行α螺旋。 在此提供了多肽中非天然氨基酸的引入。 还提供了使用双螺旋粘合剂的方法。
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公开(公告)号：US20080176278A1
公开(公告)日：2008-07-24
申请号：US11608590
申请日：2006-12-08
IPC分类号： C07K14/435 , C07H21/02 , C12P21/06
摘要： Provided herein are isolated polypeptides derived from the staphylococcal protein A protein B domain comprising a pair of anti-parallel alpha helices that are capable of binding a target. Also provided are nucleic acid sequences encoding such two helix binders, vectors containing the nucleic acid sequences encoding for two helix binders, and host cells transformed with vectors containing the nucleic acid sequences encoding for the two-helix binders. Also provided are methods of using the two helix binders.
摘要翻译： 本文提供了衍生自葡萄球菌蛋白A蛋白B结构域的分离的多肽，其包含能够结合靶标的一对反平行α螺旋。 还提供了编码这种两个螺旋粘合剂的核酸序列，含有编码两个螺旋结合物的核酸序列的载体，以及用含有编码双螺旋结合物的核酸序列的载体转化的宿主细胞。 还提供了使用两种螺旋粘合剂的方法。
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公开(公告)号：US20130071332A1
公开(公告)日：2013-03-21
申请号：US13234210
申请日：2011-09-16
申请人： Jack Mathew Webster , Bruce Fletcher Johnson , Brian Duh-Lan Lee , Chittari Pabba , Michael James Rishel
发明人： Jack Mathew Webster , Bruce Fletcher Johnson , Brian Duh-Lan Lee , Chittari Pabba , Michael James Rishel
CPC分类号： A61K51/0406 , C07B59/001
摘要： Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection.
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