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公开(公告)号:US20080127650A1
公开(公告)日:2008-06-05
申请号:US12011239
申请日:2008-01-24
CPC分类号: C12M99/00 , B82B1/00 , B82B3/00 , B82Y30/00 , B82Y40/00 , C07K14/4716 , H02N11/006 , Y10S977/729 , Y10T29/4984 , Y10T156/10
摘要: A molecular motor in which multiple concentric cylinders (or nested cones) rotate around a common longitudinal axis. Opposing complementary surfaces of the cylinders or cones are coated with complementary motor protein pairs (such as actin and myosin). The actin and myosin interact with one another in the presence of ATP to rotate the cylinders or cones relative to one another, and this rotational energy is harnessed to produce work. The concentration of ATP and the number of nested cylinders or cones can be used to control the rotational speed of the motor. The length of the cylinders can also be used to control the power generated by the motor. In another embodiment, the molecular motor includes at least two annular substrates wherein one annular substrate is coated with a first motor protein and the other annular substrate is coated with a second motor protein. The first and second motor proteins interact with each other to move the second annular relative to the first annular substrate.
摘要翻译: 一个分子马达,其中多个同心圆筒(或嵌套圆锥体)围绕共同的纵向轴线旋转。 圆柱体或锥体的互补表面涂覆有互补的运动蛋白质对(如肌动蛋白和肌球蛋白)。 肌动蛋白和肌球蛋白在ATP存在下相互作用以相对于彼此旋转圆柱体或锥体,并且利用该旋转能量来产生作用。 ATP的浓度和嵌套圆柱体或锥体的数量可用于控制电机的转速。 气缸的长度也可用于控制电机产生的电力。 在另一个实施例中,分子马达包括至少两个环形基底,其中一个环形基底涂覆有第一运动蛋白,另一个环形基底涂覆有第二运动蛋白。 第一和第二运动蛋白相互作用以相对于第一环形基底移动第二环状物。