-
公开(公告)号：US11701369B2
公开(公告)日：2023-07-18
申请号：US15513102
申请日：2015-09-28
申请人： Huahui Health Ltd.
发明人： Wenhui Li , Xiangbing Qi , Huan Yan , Yang Liu , Zhiqiang Wang , Bo Peng , Lei Zhang
IPC分类号： A61K31/585 , A61K31/575 , C07J9/00 , C07J41/00 , C07J71/00 , C07J43/00 , A61K31/58 , A61K45/06
CPC分类号： A61K31/585 , A61K31/575 , A61K31/58 , A61K45/06 , C07J9/00 , C07J9/005 , C07J41/005 , C07J41/0055 , C07J41/0061 , C07J43/003 , C07J71/0047 , A61K31/575 , A61K2300/00 , A61K31/585 , A61K2300/00 , A61K31/58 , A61K2300/00
摘要： The invention provides for treating HBV or HDV infection or inhibiting human sodium taurocholate co-transporting polypeptide (hNTCP) with a polymeric bile acid or salt thereof, and pharmaceutical compositions comprising a polymeric bile acid or salt thereof, and a second HBV or HDV medicament.
-
公开(公告)号：US11485774B2
公开(公告)日：2022-11-01
申请号：US16711861
申请日：2019-12-12
申请人： HUAHUI HEALTH LTD.
发明人： Jianhua Sui , Dan Li , Wenhui Li
摘要： Provided are human antibodies that specifically bind to HBV Pre-S1 domain ligand and inhibit HBV or HDV infection, antibodies binding to a set of amino acid residues that are critical for viral receptor engagement, and uses of these antibodies to prevent, or treat or diagnose HBV or HDV infection.
-
公开(公告)号：US20220259292A1
公开(公告)日：2022-08-18
申请号：US17628462
申请日：2020-07-20
申请人： HUAHUI HEALTH LTD.
发明人： Wenhui LI , Jianhua SUI , Pan CHEN
摘要： A method for treating HBV infection in a subject, comprising administering to the subject an anti-pre-S1 antibody or a fragment thereof at a dose of about 0.1 mg/kg to about 80 mg/kg. Also relates to an anti-pre-S1 antibody or a fragment thereof for use in treating HBV infection.
-
公开(公告)号：US20170266206A1
公开(公告)日：2017-09-21
申请号：US15513102
申请日：2015-09-28
申请人： Huahui Health Ltd.
发明人： Wenhui Li , Xiangbing Qi , Huan Yan , Yang Liu , Zhiqiang Wang , Bo Peng , Lei Zhang
IPC分类号： A61K31/585 , A61K31/58 , A61K45/06 , A61K31/575
CPC分类号： A61K31/585 , A61K31/575 , A61K31/58 , A61K45/06 , C07J9/00 , C07J9/005 , C07J41/005 , C07J41/0055 , C07J41/0061 , C07J43/003 , C07J71/0047 , A61K2300/00
摘要： The invention provides for treating HBV or HDV infection or inhibiting human sodium taurocholate co-transporting polypeptide (hNTCP) with a polymeric bile acid or salt thereof, and pharmaceutical compositions comprising a polymeric bile acid or salt thereof, and a second HBV or HDV medicament.
-
公开(公告)号：US20230348880A1
公开(公告)日：2023-11-02
申请号：US17802499
申请日：2021-02-27
发明人： Wenhui Li , Yonghe Qi , Jianhe Chen , Jianhua Sui , Juan Liu , Fengfeng Mao , Ximing Liu
IPC分类号： C12N9/48 , A61P37/02 , C12N15/63 , C07K14/735
CPC分类号： C12N9/485 , C12Y304/17023 , A61P37/02 , C12N15/63 , C07K14/70535 , C07K2319/30
摘要： A soluble ACF and a truncated form thereof, a fusion protein thereof and preparation methods therefor. A soluble ACEI and a truncated form thereof, as well as a use of the fusion protein in the preparation of a drug for an ACEI-related disease.
-
公开(公告)号：US10544205B2
公开(公告)日：2020-01-28
申请号：US15864494
申请日：2018-01-08
申请人： HUAHUI HEALTH LTD.
发明人： Jianhua Sui , Dan Li , Wenhui Li
摘要： Provided are human antibodies that specifically bind to HBV Pre-S1 domain ligand and inhibit HBV or HDV infection, antibodies binding to a set of amino acid residues that are critical for viral receptor engagement, and uses of these antibodies to prevent, or treat or diagnose HBV or HDV infection.
-
公开(公告)号：US20180148496A1
公开(公告)日：2018-05-31
申请号：US15864494
申请日：2018-01-08
申请人： HUAHUI HEALTH LTD.
发明人： Jianhua SUI , Dan LI , Wenhui LI
CPC分类号： C07K16/082 , A61K2039/505 , A61P31/20 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/732 , C07K2317/76 , C07K2317/92
摘要： Provided are human antibodies that specifically bind to HBV Pre-S1 domain ligand and inhibit HBV or HDV infection, antibodies binding to a set of amino acid residues that are critical for viral receptor engagement, and uses of these antibodies to prevent, or treat or diagnose HBV or HDV infection.
-
公开(公告)号：US20220275060A9
公开(公告)日：2022-09-01
申请号：US16711861
申请日：2019-12-12
申请人： HUAHUI HEALTH LTD.
发明人： Jianhua SUI , Dan LI , Wenhui LI
摘要： Provided are human antibodies that specifically bind to HBV Pre-S1 domain ligand and inhibit HBV or HDV infection, antibodies binding to a set of amino acid residues that are critical for viral receptor engagement, and uses of these antibodies to prevent, or treat or diagnose HBV or HDV infection.
-
公开(公告)号：US20230272067A1
公开(公告)日：2023-08-31
申请号：US18145309
申请日：2021-06-23
申请人： HUAHUI HEALTH LTD.
发明人： Jianhua SUI , Fang YANG , Linlin ZHAO , Zhizhong WEI
CPC分类号： C07K16/28 , C07K16/2818 , C07K16/2827 , C07K16/2803 , A61P35/00 , C07K2317/622
摘要： The present invention relates to anti-TIGIT antibodies and antigen-binding fragments thereof that bind to both human TIGIT and mouse TIGIT. The present application also provides are nucleotides encoding the antibodies or fragments thereof, compositions or combinations comprising the antibodies or fragments thereof, and uses of the antibodies or fragments thereof in treatment of immune-related disease such as cancers and viral infection.
-
公开(公告)号：US20180094047A1
公开(公告)日：2018-04-05
申请号：US15566555
申请日：2016-05-23
申请人： HUAHUI HEALTH LTD.
发明人： Jianhua SUI , Dan LI , Wenhui LI
CPC分类号： C07K16/082 , A61K2039/505 , A61P31/20 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/732 , C07K2317/76 , C07K2317/92
摘要： Provided are human antibodies that specifically bind to HBV Pre-S1 domain ligand and inhibit HBV or HDV infection, antibodies binding to a set of amino acid residues that are critical for viral receptor engagement, and uses of these antibodies to prevent, or treat or diagnose HBV or HDV infection.
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.014 秒)
