发明授权
- 专利标题: Polymeric bile acid derivatives inhibit Hepatitis B and D virus and NTCP transport
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申请号: US15513102申请日: 2015-09-28
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公开(公告)号: US11701369B2公开(公告)日: 2023-07-18
- 发明人: Wenhui Li , Xiangbing Qi , Huan Yan , Yang Liu , Zhiqiang Wang , Bo Peng , Lei Zhang
- 申请人: Huahui Health Ltd.
- 申请人地址: CN Beijing
- 专利权人: Huahui Health Ltd.
- 当前专利权人: Huahui Health Ltd.
- 当前专利权人地址: CN Beijing
- 代理机构: Nixon & Vanderhye, P.C.
- 优先权: WO TCN2014087655 2014.09.28
- 国际申请: PCT/CN2015/091000 2015.09.28
- 国际公布: WO2016/045642A 2016.03.31
- 进入国家日期: 2017-03-21
- 主分类号: A61K31/585
- IPC分类号: A61K31/585 ; A61K31/575 ; C07J9/00 ; C07J41/00 ; C07J71/00 ; C07J43/00 ; A61K31/58 ; A61K45/06
摘要:
The invention provides for treating HBV or HDV infection or inhibiting human sodium taurocholate co-transporting polypeptide (hNTCP) with a polymeric bile acid or salt thereof, and pharmaceutical compositions comprising a polymeric bile acid or salt thereof, and a second HBV or HDV medicament.
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