-
1.发明授权
公开(公告)号：US4370280A
公开(公告)日：1983-01-25
申请号：US308734
申请日：1981-10-05
申请人： Hermann Oediger , Folker Lieb , Hans Disselnkotter
发明人： Hermann Oediger , Folker Lieb , Hans Disselnkotter
IPC分类号： C07F9/38 , C07F9/40 , C07C120/00 , C07C121/36
CPC分类号： C07F9/3808
摘要： The invention relates to phosphonodroxyacetonitrile and a process for its production which comprises reacting phosphono formaldehyde, in salt form, with hydrocyanic acid (then, if desired, converting the free phosphonohydroxyacetonitrile to salt thereof. The phosphonohydroxyacetonitrile is useful, for example, as an intermediate for the production of phosphonohydroxyacetic acid, an antiviral agent.
摘要翻译： 本发明涉及膦酰基羟基乙腈及其制备方法，其包括以盐形式的膦酰甲醛与氢氰酸反应（然后，如果需要，将游离膦酰羟基乙腈转化为其盐），膦酰羟基乙腈可用作例如 生产膦酰羟基乙酸，一种抗病毒剂。
-
公开(公告)号：US3936442A
公开(公告)日：1976-02-03
申请号：US426308
申请日：1973-12-19
IPC分类号： A61K31/43 , C07C275/60 , C07D499/64 , C07D499/58
CPC分类号： C07D499/64 , A61K31/43 , C07C275/60 , C07D499/68
摘要： 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
摘要翻译： 6-（α-3-酰基 - 脲基乙酰胺基） - 青霉烷酸及其药学上可接受的无毒盐，其中存在于3-位的氮原子的氢原子被取代，对革兰氏阳性和革兰氏阴性有效 感染，特别是克雷伯杆菌感染。
-
公开(公告)号：US3974140A
公开(公告)日：1976-08-10
申请号：US604480
申请日：1975-08-13
IPC分类号： A61K31/43 , C07C275/60 , C07D499/64 , C07D499/68 , C07D499/70
CPC分类号： C07D499/64 , A61K31/43 , C07C275/60 , C07D499/68
摘要： 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
摘要翻译： 6-（α-3-酰基 - 脲基乙酰胺基） - 青霉烷酸及其药学上可接受的无毒盐，其中存在于3-位的氮原子的氢原子被取代，对革兰氏阳性和革兰氏阴性有效 感染，特别是克雷伯杆菌感染。
-
4.发明授权
公开(公告)号：US4348332A
公开(公告)日：1982-09-07
申请号：US308717
申请日：1981-10-05
申请人： Hermann Oediger , Folker Lieb , Hans Disselnkotter
发明人： Hermann Oediger , Folker Lieb , Hans Disselnkotter
IPC分类号： C07F9/38 , C07F9/40 , C07D213/18
CPC分类号： C07F9/3891 , C07F9/3808
摘要： The invention relates to phosphonoformaldehyde of the formula ##STR1## Also included in the invention is a method for the manufacture of said phosphonoformaldehyde in which a dialkoxymethane phosphonic acid is warmed with water (then reacted with a base if a salt is desired). Phosphonoformaldehyde is an intermediate for the manufactureof phosphonohydroxy acetic acid, which is an antiviral agent.
摘要翻译： 本发明涉及下式的膦酰甲醛。本发明还包括制备所述膦酰甲醛的方法，其中二烷氧基甲烷膦酸用水加热（然后如果需要盐则与碱反应）。 膦酰甲醛是制备作为抗病毒剂的膦酰羟基乙酸的中间体。
-
公开(公告)号：US3959258A
公开(公告)日：1976-05-25
申请号：US425966
申请日：1973-12-19
IPC分类号： A61K31/43 , C07C275/60 , C07D233/38 , C07D261/18 , C07D307/68 , C07D333/24 , C07D333/38 , C07D499/68 , C07F7/08
CPC分类号： C07D499/64 , A61K31/43 , C07C275/60 , C07D233/38 , C07D261/18 , C07D307/68 , C07D333/24 , C07D333/38 , C07D499/68 , C07F7/08
摘要： 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
-
公开(公告)号：US3933795A
公开(公告)日：1976-01-20
申请号：US426187
申请日：1973-12-19
IPC分类号： A61K31/43 , C07C275/60 , C07D499/64 , C07D499/44
CPC分类号： C07D499/64 , A61K31/43 , C07C275/60 , C07D499/68
摘要： 6-(.alpha.-3-Acyl-unreidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
摘要翻译： 6-（α-3-酰基 - 乙酰氨基乙酰氨基） - 青霉烷酸及其药学上可接受的无毒盐，其中存在于3-位上的氮原子的氢原子被取代，对革兰氏阳性和革兰氏阴性有效 感染，特别是克雷伯杆菌感染。
-
7.发明授权
公开(公告)号：US4447367A
公开(公告)日：1984-05-08
申请号：US370890
申请日：1982-04-22
申请人： Hermann Oediger , Folker Lieb , Hans Disselnkotter
发明人： Hermann Oediger , Folker Lieb , Hans Disselnkotter
CPC分类号： C07F9/3891 , C07F9/3808
摘要： The invention relates to phosphonoformaldehyde of the formula ##STR1## Also included in the invention is a method for the manufacture of said phosphonoformaldehyde in which a dialkoxymethane phosphonic acid is warmed with water (then reacted with a base if a salt is desired.) Phosphonoformaldehyde is an intermediate for the manufacture of phosphonohydroxy acetic acid, which is an antiviral agent.
摘要翻译： 本发明涉及下式的膦酰甲醛本发明还包括制备所述膦酰甲醛的方法，其中二烷氧基甲烷膦酸用水加热（然后如果需要盐则与碱反应）。膦酰甲醛是 用于制备作为抗病毒剂的膦酰羟基乙酸的中间体。
-
公开(公告)号：US4016282A
公开(公告)日：1977-04-05
申请号：US568384
申请日：1975-04-16
IPC分类号： A61K31/43 , C07C275/60
CPC分类号： C07D499/64 , A61K31/43 , C07C275/60 , C07D499/68
摘要： 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
摘要翻译： 6-（α-3-酰基 - 脲基乙酰胺基） - 青霉烷酸及其药学上可接受的无毒盐，其中存在于3-位的氮原子的氢原子被取代，对革兰氏阳性和革兰氏阴性有效 感染，特别是克雷伯杆菌感染。
-
公开(公告)号：US3980792A
公开(公告)日：1976-09-14
申请号：US568477
申请日：1975-04-16
IPC分类号： A61K31/43 , C07C275/60
CPC分类号： C07D499/64 , A61K31/43 , C07C275/60 , C07D499/68
摘要： 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
-
10.发明授权Ureidoacetamido-penicillins for treating bacterial infections 失效用于治疗细菌感染的UREIDOACETAMIDO-PENICILLIN
公开(公告)号：US3978223A
公开(公告)日：1976-08-31
申请号：US568419
申请日：1975-04-16
IPC分类号： A61K31/43 , C07C275/60
CPC分类号： C07D499/64 , A61K31/43 , C07C275/60 , C07D499/68
摘要： 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.02 秒)
