公开(公告)号：US09952293B2

公开(公告)日：2018-04-24

申请号：US15395454

申请日：2016-12-30

Applicant: GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF COMMERCE

Inventor： Daniel B. Gopman ,  Robert D. Shull

IPC: H01L41/08 ,  G01R33/09 ,  G11C11/16 ,  H01L43/08 ,  H01L41/09

CPC classification number: G01R33/093 ,  G01R33/098 ,  G11C11/161 ,  G11C11/1675 ,  H01L41/0986 ,  H01L43/08

Abstract: A magnetic piezoelectric composite adjusts magnetic anisotropy strength in a bimetallic member and includes: a piezoelectric layer to produce a strain in response to receipt of a strain voltage; and the bimetallic member disposed on the piezoelectric layer, the bimetallic member including: a plurality of metal layers, such that a second metal layer is interposed between a pair of first metal layers, the bimetallic member being ferromagnetic; and a magnetic anisotropy strength that changes in response to receipt of the strain from the piezoelectric layer.

公开(公告)号：US20170254810A1

公开(公告)日：2017-09-07

申请号：US15411975

申请日：2017-01-21

Applicant: GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF COMMERCE

Inventor： ERICA MCJIMPSEY, IV

IPC: G01N33/574 ,  G01N33/68

CPC classification number: G01N33/57434

Abstract: A process for detecting prostate cancer biomarkers includes: subjecting seminal plasma fluid to western blot analysis; identifying a first prostate specific antigen (PSA) subform in the seminal plasma fluid, based on the western blot analysis; identifying a second PSA subform in the seminal plasma fluid, based on the western blot analysis; and quantifying a first amount of the first PSA subform and a second amount of the second PSA subform in the seminal plasma fluid to detect prostate cancer biomarkers in a subject from which the seminal plasma fluid was provided.

公开(公告)号：US11519987B2

公开(公告)日：2022-12-06

申请号：US17301509

申请日：2021-04-05

Applicant: Case Western Reserve University ,  Government of the United States, as represented by the Secretary of Commerce ,  The Regents of the University of Colorado, a body corporate

Inventor： Kathryn Keenan ,  Megan Poorman ,  Rasim Boyacioglu ,  Mark A. Griswold

IPC: G01R33/50 ,  G01R33/56 ,  A61B5/055 ,  A61B5/00 ,  G01R33/385

Abstract: A method for temperature quantification using magnetic resonance fingerprinting (MRF) includes acquiring MRF data from a region of interest in a subject using an MRF pulse sequence with smoothly varying RF phase for MR resonant frequencies that is played out continuously. For each of a plurality of time intervals during acquisition of the MRF data the method further includes comparing a set of the MRF data associated with the time interval to an MRF dictionary to determine at least one quantitative parameter of the acquired MRF data, determining a temperature change based on the at least one quantitative parameter and generating a quantitative map of the temperature change in the region of interest. The region of interest can include aqueous and adipose tissue.

公开(公告)号：US20170236993A1

公开(公告)日：2017-08-17

申请号：US15395454

申请日：2016-12-30

Applicant: GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF COMMERCE

Inventor： DANIEL B. GOPMAN ,  ROBERT D. SHULL

IPC: H01L41/113 ,  H01L41/18 ,  H01L41/09

CPC classification number: G01R33/093 ,  G01R33/098 ,  G11C11/161 ,  G11C11/1675 ,  H01L41/0986 ,  H01L43/08

Abstract: A magnetic piezoelectric composite adjusts magnetic anisotropy strength in a bimetallic member and includes: a piezoelectric layer to produce a strain in response to receipt of a strain voltage; and the bimetallic member disposed on the piezoelectric layer, the bimetallic member including: a plurality of metal layers, such that a second metal layer is interposed between a pair of first metal layers, the bimetallic member being ferromagnetic; and a magnetic anisotropy strength that changes in response to receipt of the strain from the piezoelectric layer.

公开(公告)号：US20210311146A1

公开(公告)日：2021-10-07

申请号：US17301509

申请日：2021-04-05

Applicant: Case Western Reserve University ,  Government of the United States, as represented by the Secretary of Commerce ,  The Regents of the University of Colorado, a body corporate

Inventor： Kathryn Keenan ,  Megan Poorman ,  Rasim Boyacioglu ,  Mark A. Griswold

IPC: G01R33/50 ,  G01R33/56 ,  G01R33/385 ,  A61B5/00 ,  A61B5/055

Abstract: A method for temperature quantification using magnetic resonance fingerprinting (MRF) includes acquiring MRF data from a region of interest in a subject using an MRF pulse sequence with smoothly varying RF phase for MR resonant frequencies that is played out continuously. For each of a plurality of time intervals during acquisition of the MRF data the method further includes comparing a set of the MRF data associated with the time interval to an MRF dictionary to determine at least one quantitative parameter of the acquired MRF data, determining a temperature change based on the at least one quantitative parameter and generating a quantitative map of the temperature change in the region of interest. The region of interest can include aqueous and adipose tissue.