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1.发明授权Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanion for the treatment of AIDS 有权包含衍生自与用于治疗AIDS的聚阴离子偶联的CD4受体的肽的共轭分子公开(公告)号：US09295730B2
公开(公告)日：2016-03-29
申请号：US12866158
申请日：2009-01-27
Applicant: Françoise Baleux , David Bonnaffe , Hugues Lortat-Jacob , Latino Loureiro-Morais
Inventor： Françoise Baleux , David Bonnaffe , Hugues Lortat-Jacob , Latino Loureiro-Morais
IPC: A61K38/14 , A61K38/16 , A01N43/04 , A61K31/70 , A61K31/727 , A01N37/18 , A61K38/00 , A61P31/18 , A61P31/10 , C07K9/00 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , A61K47/48 , A61K38/17 , C07K14/73
CPC classification number: A61K47/48276 , A61K38/00 , A61K38/14 , A61K38/16 , A61K38/1761 , A61K47/61 , A61K47/6425 , C07K14/70514
Abstract: This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Such a conjugated molecule can be used in antiviral treatment, namely in the treatment of AIDS.
Abstract translation: 本发明涉及包含通过连接体偶联到有机分子的CD4受体的肽的共轭分子及其制备方法。 这种共轭分子可用于抗病毒治疗，即用于治疗AIDS。
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2.发明申请NEW CONJUGATED MOLECULES COMPRISING A PEPTIDE DERIVED FROM THE CD4 RECEPTOR COUPLED TO A POLYANIONIC POLYPEPTIDE FOR THE TREATMENT OF AIDS 有权包含从CD4受体转移到用于治疗艾滋病的POLYANIONIC POLYPEPTIDE的肽的新的结合分子公开(公告)号：US20140107043A1
公开(公告)日：2014-04-17
申请号：US14005688
申请日：2012-03-16
Applicant: Françoise Baleux , Hugues Lortat-Jacob , David Bonnaffe
Inventor： Françoise Baleux , Hugues Lortat-Jacob , David Bonnaffe
IPC: A61K47/48
CPC classification number: A61K47/48276 , A61K38/16 , A61K38/177 , A61K38/195 , A61K47/6425 , C07K14/70514 , C07K14/70539 , C07K17/02 , C07K2319/00
Abstract: This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Said organic molecule comprises a 5 to 21 amino acid anionic polypeptide. Such a conjugated molecule can be used in antiviral treatment, namely in the treatment of AIDS.
Abstract translation: 本发明涉及包含通过连接体偶联到有机分子的CD4受体的肽的共轭分子及其制备方法。 所述有机分子包含5至21个氨基酸的阴离子多肽。 这样的共轭分子可用于抗病毒治疗，即用于治疗AIDS。
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3.发明申请CONJUGATED MOLECULES COMPRISING A PEPTIDE DERIVED FROM THE CD4 RECEPTOR COUPLED TO A POLYANION FOR THE TREATMENT OF AIDS 有权包含从CD4受体偶联到治疗艾滋病的聚合物中产生的肽的结合分子公开(公告)号：US20110105412A1
公开(公告)日：2011-05-05
申请号：US12866158
申请日：2009-01-27
Applicant: Françoise Baleux , David Bonnaffe , Hugues Lortat-Jacob , Latino Loureiro-Morais
Inventor： Françoise Baleux , David Bonnaffe , Hugues Lortat-Jacob , Latino Loureiro-Morais
CPC classification number: A61K47/48276 , A61K38/00 , A61K38/14 , A61K38/16 , A61K38/1761 , A61K47/61 , A61K47/6425 , C07K14/70514
Abstract: This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Such a conjugated molecule can be used in antiviral treatment, namely in the treatment of AIDS.
Abstract translation: 本发明涉及包含通过连接体偶联到有机分子的CD4受体的肽的共轭分子及其制备方法。 这样的共轭分子可用于抗病毒治疗，即用于治疗AIDS。
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4.发明授权Glycoconjugates and their use as potential vaccines against infection by Shigella flexneri 有权糖缀合物及其作为抵抗志贺氏菌感染的潜在疫苗的用途公开(公告)号：US08124380B2
公开(公告)日：2012-02-28
申请号：US10563221
申请日：2004-07-02
Applicant: Armelle Phalipon , Farida Nato , Laurence Mulard , Philippe Sansonetti , Françoise Baleux , Frédéric Belot , Cyrille Grandjean
Inventor： Armelle Phalipon , Farida Nato , Laurence Mulard , Philippe Sansonetti , Françoise Baleux , Frédéric Belot , Cyrille Grandjean
CPC classification number: A61K39/0283 , A61K47/557 , A61K47/61 , A61K47/6415 , A61K47/646 , A61K2039/6031 , A61K2039/6037 , A61K2039/625 , C07H3/06 , C07K16/1228 , C07K2317/565 , C08B37/006 , G01N33/563 , G01N33/56916 , Y02A50/476
Abstract: A conjugate molecule comprising an oligo- or polysaccharide covalently bound to a carrier and its use as potential vaccine against infection by S. Flexneri.
Abstract translation: 共轭分子包含与载体共价结合的寡糖或多糖，并且其用作针对S.Flexneri感染的潜在疫苗。
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Patent Agency Ranking
5.发明授权Glycoconjugates and their use as potential vaccines against infection by Shigella flexneri 有权糖缀合物及其作为抵抗志贺氏菌感染的潜在疫苗的用途公开(公告)号：US09446109B2
公开(公告)日：2016-09-20
申请号：US13325511
申请日：2011-12-14
Applicant: Armelle Phalipon , Farida Nato , Laurence Mulard , Philippe Sansonetti , Françoise Baleux , Frédéric Belot , Cyrille Grandjean
Inventor： Armelle Phalipon , Farida Nato , Laurence Mulard , Philippe Sansonetti , Françoise Baleux , Frédéric Belot , Cyrille Grandjean
IPC: C12P19/00 , C12P19/12 , C07K1/00 , A61K39/112 , A61K47/48 , C07K16/12 , G01N33/563 , G01N33/569 , C07H3/06 , C08B37/00 , A61K39/00
CPC classification number: A61K39/0283 , A61K47/557 , A61K47/61 , A61K47/6415 , A61K47/646 , A61K2039/6031 , A61K2039/6037 , A61K2039/625 , C07H3/06 , C07K16/1228 , C07K2317/565 , C08B37/006 , G01N33/563 , G01N33/56916 , Y02A50/476
Abstract: A conjugate molecule comprising an oligo- or polysaccharide covalently bound to a carrier and its use as potential vaccine against infection by S. Flexneri.
Abstract translation: 共轭分子包含与载体共价结合的寡糖或多糖，并且其用作针对S.Flexneri感染的潜在疫苗。
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6.发明授权Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanionic polypeptide for the treatment of AIDS 有权包含衍生自与用于治疗AIDS的聚阴离子多肽偶联的CD4受体的肽的共轭分子公开(公告)号：US09078928B2
公开(公告)日：2015-07-14
申请号：US14005688
申请日：2012-03-16
Applicant: Françoise Baleux , Hugues Lortat-Jacob , David Bonnaffe
Inventor： Françoise Baleux , Hugues Lortat-Jacob , David Bonnaffe
CPC classification number: A61K47/48276 , A61K38/16 , A61K38/177 , A61K38/195 , A61K47/6425 , C07K14/70514 , C07K14/70539 , C07K17/02 , C07K2319/00
Abstract: This invention relates to a conjugated molecule comprising a peptide derived from the CD4 receptor coupled to an organic molecule by means of a linker as well as a process for its preparation. Said organic molecule comprises a 5 to 21 amino acid anionic polypeptide. Such a conjugated molecule can be used in antiviral treatment, namely in the treatment of AIDS.
Abstract translation: 本发明涉及包含通过连接体偶联到有机分子的CD4受体的肽的共轭分子及其制备方法。 所述有机分子包含5至21个氨基酸的阴离子多肽。 这样的共轭分子可用于抗病毒治疗，即用于治疗AIDS。
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7.发明申请GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI 有权谷氨酸钠及其作为潜在的疫苗使用，可以通过SHIGELLA FLEXNERI感染公开(公告)号：US20130243751A1
公开(公告)日：2013-09-19
申请号：US13325511
申请日：2011-12-14
Applicant: Armelle PHALIPON , Farida Nato , Laurence Mulard , Philippe Sansonetti , Françoise Baleux , Frédéric Belot , Cyrille Grandjean
Inventor： Armelle PHALIPON , Farida Nato , Laurence Mulard , Philippe Sansonetti , Françoise Baleux , Frédéric Belot , Cyrille Grandjean
IPC: A61K39/112 , C07K16/12 , C08B37/00 , C07H3/06
CPC classification number: A61K39/0283 , A61K47/557 , A61K47/61 , A61K47/6415 , A61K47/646 , A61K2039/6031 , A61K2039/6037 , A61K2039/625 , C07H3/06 , C07K16/1228 , C07K2317/565 , C08B37/006 , G01N33/563 , G01N33/56916 , Y02A50/476
Abstract: A conjugate molecule comprising an oligo- or polysaccharide covalently bound to a carrier and its use as potential vaccine against infection by S. Flexneri.
Abstract translation: 共轭分子包含与载体共价结合的寡糖或多糖，并且其用作针对S.Flexneri感染的潜在疫苗。
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公开(公告)号：US20110015368A1
公开(公告)日：2011-01-20
申请号：US12375545
申请日：2007-08-03
Applicant: Françoise Baleux , David Bonnaffe , Hugues Lortat-Jacob
Inventor： Françoise Baleux , David Bonnaffe , Hugues Lortat-Jacob
CPC classification number: C07K14/70514
Abstract: The present invention relates to an activated peptide derived from the CD4 receptor, which is capable of coupling by covalent bonding to an organic molecule and thus makes it possible to generate multiple potentially antiviral derivatives. The present invention also relates to a conjugated molecule comprising the CD4-receptor-derived peptide and an organic molecule, preferably the GPR1 peptide or a polyanion. Such a conjugated molecule can in particular be used in antiviral treatments, in particular the treatment of AIDS. The invention also relates to the methods for preparing the activated peptide derived from the CD4 receptor and the conjugated molecule.
Abstract translation: 本发明涉及从CD4受体衍生的活化肽，其能够通过共价键与有机分子偶联，从而使得可能产生多种潜在的抗病毒衍生物。 本发明还涉及包含CD4受体来源的肽和有机分子，优选GPR1肽或聚阴离子的共轭分子。 这种共轭分子特别可用于抗病毒治疗，特别是AIDS的治疗。 本发明还涉及制备衍生自CD4受体和共轭分子的活化肽的方法。
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公开(公告)号：US07820142B2
公开(公告)日：2010-10-26
申请号：US10953095
申请日：2004-09-30
Applicant: Gilles Marchal , Félix Romain , Pascale Pescher , Françoise Baleux , Daniel Scott-Algara , Laurence Mulard
Inventor： Gilles Marchal , Félix Romain , Pascale Pescher , Françoise Baleux , Daniel Scott-Algara , Laurence Mulard
IPC: A61K49/00
CPC classification number: G01N33/5695
Abstract: The invention relates to immunogenic glycopeptides derived from pathogenic microorganisms, which can be used for immunization and diagnosing infections dye to such pathogenic microorganisms and also to method for the selection and preparation thereof.
Abstract translation: 本发明涉及来自病原微生物的免疫原性糖肽，其可用于对这种病原微生物的感染染色的免疫和诊断，以及其选择和制备方法。
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