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公开(公告)号：US20230293233A1
公开(公告)日：2023-09-21
申请号：US18295970
申请日：2023-04-05
Applicant: Fotona d.o.o.
Inventor： Matjaz LUKAC , Franci BAJD , Marko KAZIC , Zdenko VIZINTIN , Tadej PERHAVEC
CPC classification number: A61B18/20 , A61B1/307 , A61B2018/00559
Abstract: A treatment method for non-ablative tissue regeneration includes directing at least one laser pulse having a wavelength onto a tissue surface of a human or animal body, and controlling an energy delivery time ted of the at least one laser pulse, during which the second half of the pulse energy is delivered, to be sufficiently short, so that, given the wavelength and thus a corresponding penetration depth δ of the at least one laser pulse, a thermal exposure time texp of the tissue surface is smaller than 900 microseconds. The thermal exposure time texp of the tissue surface is defined as a time interval in which the temperature of the tissue surface is above To + (Tmax - To)/2, wherein To defines the initial temperature of the tissue surface, before the laser pulse arrives, and Tmax is a maximal temperature of the tissue surface.
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公开(公告)号：US11490945B2
公开(公告)日：2022-11-08
申请号：US16245806
申请日：2019-01-11
Applicant: Fotona d.o.o.
Inventor： Marko Kazic , Nejc Lukac , Blaz Tasic Muc , Matjaz Lukac
Abstract: An apparatus for cooling tissues which are treated with an energy-based device, such as a laser, is disclosed. The apparatus comprises a spray nozzle which generates an atomized liquid spray for the treatment area, wherein the atomized liquid spray is based on a mixture of liquid and gas. Further, the spray nozzle comprises at least one liquid outlet which ejects a liquid, and at least one gas outlet which ejects a gas stream. Besides, the apparatus for cooling comprises at least one delivery means for delivering pressurized gas to the spray nozzle; and a pumping means for the liquid, wherein the pumping means is configured to operate in pulses.
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公开(公告)号：US10518299B2
公开(公告)日：2019-12-31
申请号：US15227068
申请日：2016-08-03
Applicant: Fotona d.o.o
Inventor： Nejc Lukac , Matjaz Lukac , Matija Jezersek , Peter Gregorcic
Abstract: The application relates to a cleaning system configured for cleaning of cavities filled with a liquid, including fragmentation, debridement, material removal, irrigation, disinfection, and decontamination. The cleaning system includes an electromagnetic radiation system and a liquid. A treatment handpiece irradiates the liquid within a cavity with a radiation beam, producing a first vapor bubble using first pulse, and, at a different location, a second vapor bubble using a second pulse. The pulse repetition time is adjusted to ensure efficacy, for example such that an onset time of the second vapor bubble is within the first contraction phase of the first vapor bubble, when the first vapor bubble has contracted from its maximal volume to a size in a range from about 0.7 to about 0.1 of the maximal volume.
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公开(公告)号：US12042665B2
公开(公告)日：2024-07-23
申请号：US16574759
申请日：2019-09-18
Applicant: Fotona d.o.o.
Inventor： Marcelo Tettamanti , Julio Cezar Velez Ocampo , Sebastian Velez Ocampo , Dejan Skrabelj , Irena Hreljac
CPC classification number: A61N5/0616 , A61B18/203 , A61N5/062 , A61N2005/0626 , A61N5/067
Abstract: Methods and apparatus for treating melasma and/or related hyperpigmentation disorders of a patient are disclosed. The treatment includes delivering laser pulses onto a body of the patient, wherein the delivering laser pulses includes two or more of the following steps: 1) delivering laser pulses p1 onto the body, wherein each pulse of the laser pulses p1 is configured to have a diameter of at least 100 μm and a duration of at most 1 μs; 2) delivering laser pulses p2 onto the body, wherein each pulse of the laser pulses p2 is configured to have a diameter of at least 100 μm and a duration of more than 1 μs; 3) delivering laser pulses p3 onto the body, wherein each pulse of the laser pulses p3 is configured to comprise a plurality of microbeams, each microbeam having a diameter below 1 mm.
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公开(公告)号：US12016609B2
公开(公告)日：2024-06-25
申请号：US18053506
申请日：2022-11-08
Applicant: Fotona d.o.o.
Inventor： Marko Kazic , Nejc Lukac , Blaz Tasic Muc , Matjaz Lukac
CPC classification number: A61B18/0218 , A61B18/203 , A61C1/0046 , A61C1/0061 , A61C17/028 , A61N5/0616 , A61B2018/00005 , A61B2018/00029 , A61B2018/00452 , A61B2090/049
Abstract: An apparatus for cooling tissues which are treated with an energy-based device, such as a laser, is disclosed. The apparatus comprises a spray nozzle which generates an atomized liquid spray for the treatment area, wherein the atomized liquid spray is based on a mixture of liquid and gas. Further, the spray nozzle comprises at least one liquid outlet which ejects a liquid, and at least one gas outlet which ejects a gas stream. Besides, the apparatus for cooling comprises at least one delivery means for delivering pressurized gas to the spray nozzle; and a pumping means for the liquid, wherein the pumping means is configured to operate in pulses.
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Patent Agency Ranking
公开(公告)号：US20230064019A1
公开(公告)日：2023-03-02
申请号：US18053506
申请日：2022-11-08
Applicant: Fotona d.o.o.
Inventor： Marko KAZIC , Nejc LUKAC , Blaz TASIC MUC , Matjaz LUKAC
IPC: A61B18/02 , A61B18/20 , A61C1/00 , A61N5/06 , A61C17/028
Abstract: An apparatus for cooling tissues which are treated with an energy-based device, such as a laser, is disclosed. The apparatus comprises a spray nozzle which generates an atomized liquid spray for the treatment area, wherein the atomized liquid spray is based on a mixture of liquid and gas. Further, the spray nozzle comprises at least one liquid outlet which ejects a liquid, and at least one gas outlet which ejects a gas stream. Besides, the apparatus for cooling comprises at least one delivery means for delivering pressurized gas to the spray nozzle; and a pumping means for the liquid, wherein the pumping means is configured to operate in pulses.
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公开(公告)号：US20220266055A1
公开(公告)日：2022-08-25
申请号：US17674550
申请日：2022-02-17
Applicant: Fotona d.o.o.
Inventor： Matjaz LUKAC , Nejc LUKAC , Blaz TASIC MUC , Anze ZORMAN , Tadej PERHAVEC
Abstract: The present disclosure relates to a method and an apparatus for generating a laser pulse sequence for application to a predetermined target tissue. Means are provided for setting a cumulative fluence Fs of the laser pulse sequence. Means are provided for determining a duration of the laser pulse sequence as a function of the cumulative fluence Fs such that the predetermined target tissue is heated to a final temperature that is within a predetermined range.
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公开(公告)号：US20190239938A1
公开(公告)日：2019-08-08
申请号：US16245806
申请日：2019-01-11
Applicant: Fotona d.o.o.
Inventor： Marko KAZIC , Nejc LUKAC , Blaz TASIC MUC , Matjaz LUKAC
IPC: A61B18/02 , A61B18/20 , A61C17/028 , A61C1/00
CPC classification number: A61B18/203 , A61B2018/00005 , A61C1/0046 , A61C1/0061 , A61N5/0616
Abstract: An apparatus for cooling tissues which are treated with an energy-based device, such as a laser, is disclosed. The apparatus comprises a spray nozzle which generates an atomized liquid spray for the treatment area, wherein the atomized liquid spray is based on a mixture of liquid and gas. Further, the spray nozzle comprises at least one liquid outlet which ejects a liquid, and at least one gas outlet which ejects a gas stream. Besides, the apparatus for cooling comprises at least one delivery means for delivering pressurized gas to the spray nozzle; and a pumping means for the liquid, wherein the pumping means is configured to operate in pulses.
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公开(公告)号：US12064178B2
公开(公告)日：2024-08-20
申请号：US18295970
申请日：2023-04-05
Applicant: Fotona d.o.o.
Inventor： Matjaz Lukac , Franci Bajd , Marko Kazic , Zdenko Vizintin , Tadej Perhavec
CPC classification number: A61B18/20 , A61B1/307 , A61B2018/00327 , A61B2018/0047 , A61B2018/00476 , A61B2018/00517 , A61B2018/00559 , A61B2018/00738 , A61B2018/00791
Abstract: A treatment method for non-ablative tissue regeneration includes directing at least one laser pulse having a wavelength onto a tissue surface of a human or animal body, and controlling an energy delivery time ted of the at least one laser pulse, during which the second half of the pulse energy is delivered, to be sufficiently short, so that, given the wavelength and thus a corresponding penetration depth δ of the at least one laser pulse, a thermal exposure time texp of the tissue surface is smaller than 900 microseconds. The thermal exposure time texp of the tissue surface is defined as a time interval in which the temperature of the tissue surface is above T0+(Tmax−T0)/2, wherein T0 defines the initial temperature of the tissue surface, before the laser pulse arrives, and Tmax is a maximal temperature of the tissue surface.
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公开(公告)号：US11964311B2
公开(公告)日：2024-04-23
申请号：US16691754
申请日：2019-11-22
Applicant: FOTONA D.O.O.
Inventor： Nejc Lukac , Matjaz Lukac , Matija Jezersek , Peter Gregorcic
IPC: B08B7/02 , A61B18/26 , A61C1/00 , A61C5/40 , A61C17/02 , A61L2/00 , B08B3/10 , A61B17/00 , A61B18/00
CPC classification number: B08B7/02 , A61B18/26 , A61C1/0046 , A61C5/40 , A61C17/0202 , A61L2/0029 , B08B3/102 , A61B2017/00176 , A61B2017/00194 , A61B2018/00404 , A61B2018/00505 , A61B2018/263 , A61L2202/11 , A61L2202/17
Abstract: The application relates to a cleaning system configured for cleaning of cavities filled with a liquid, including fragmentation, debridement, material removal, irrigation, disinfection, and decontamination. The cleaning system includes an electromagnetic radiation system and a liquid. A treatment handpiece irradiates the liquid within a cavity with a radiation beam, producing a first vapor bubble using first pulse, and, at a different location, a second vapor bubble using a second pulse. The pulse repetition time is adjusted to ensure efficacy, for example such that an onset time of the second vapor bubble is within the first contraction phase of the first vapor bubble, when the first vapor bubble has contracted from its maximal volume to a size in a range from about 0.7 to about 0.1 of the maximal volume.
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