公开(公告)号：US20240339218A1

公开(公告)日：2024-10-10

申请号：US18681425

申请日：2022-08-03

申请人： Deepull Diagnostics S.L.

发明人： Jordi CARRERA FABRA ,  Rafael BRU GIBERT ,  Richard Max IVEY

IPC分类号： G16H50/20 ,  C12Q1/18 ,  C12Q1/686 ,  C12Q1/689 ,  G01N21/65 ,  G16B25/20 ,  G16B40/10 ,  G16H10/60 ,  G16H20/10

CPC分类号： G16H50/20 ,  C12Q1/18 ,  C12Q1/686 ,  C12Q1/689 ,  G01N21/65 ,  G16B25/20 ,  G16B40/10 ,  G16H10/60 ,  G16H20/10

摘要： A sepsis detection system includes a first subsystem configured to detect a presence of an infection in a patient, a second subsystem configured to detect a presence of a dysregulated host response in the patient, a third subsystem configured to detect organ dysfunction in the patient, a fourth subsystem configured to detect antimicrobial resistance (AMR) of a pathogen in the patient, and a processing device. The first, second, third, and fourth subsystems and the processing device are communicatively coupled together via a network. The processing device is configured to determine a presence of sepsis in the patient based on the presence of the infection, the presence of the dysregulated host response, and clinical data indicative of the organ dysfunction in the patient. The subsystems utilize at least one of polymerase chain reaction (PCR) processing. Raman spectroscopy, clinical data, electronic health record (EHR) data, and antimicrobial susceptibility testing (AST).