2-Alkyl-2-(3-oxoalkyl)-1,3-cyclopentadiones
    4.
    发明授权
    2-Alkyl-2-(3-oxoalkyl)-1,3-cyclopentadiones 失效
    2-烷基-2-(3-氧代烷基)-1,3-戊二酸二乙酯

    公开(公告)号:US3975442A

    公开(公告)日:1976-08-17

    申请号:US467355

    申请日:1974-05-06

    IPC分类号: C07C49/27

    摘要: Optically active organic compounds are prepared starting from optically inactive reactants by means of an optically active agent which influences the course of the reaction. In particular optically active compounds having a "meso" type carbon atom undergo an intramolecular ring closure in the presence of an optically active agent to yield an optically active product having one additional ring. The present process is particularly useful in the preparation of optically active bicyclic diketones which are important intermediates in the total synthesis of steroids.

    摘要翻译: 通过影响反应过程的光学活性剂由光学惰性反应物开始制备光学活性的有机化合物。 特别是具有“内消旋”型碳原子的光学活性化合物在光学活性剂的存在下进行分子内闭环,得到具有一个另外的环的光学活性产物。 本方法特别可用于制备在全合成类固醇中重要的中间体的光学双环二酮。