公开(公告)号：US20110151486A1

公开(公告)日：2011-06-23

申请号：US12908803

申请日：2010-10-20

Applicant: Thomas M. Zappia ,  Brandon T. Johnson ,  David Butz

Inventor： Thomas M. Zappia ,  Brandon T. Johnson ,  David Butz

IPC: G01N33/53 ,  C12M1/34

CPC classification number: G01N33/558

Abstract: Methods and systems to remove gas bubbles from liquids and to improve uniform fluid flow through a region of a membrane in a microfluidic device, including to reduce, remove, and/or prevent gas bubbles on a surface of a porous membrane. An example membrane bubble trap system may include a fluid channel connected to a bubble pathway that surrounds an opening sealed with a membrane. The bubble pathway may be configured to collect bubbles in fluid that passes through the membrane through buoyancy forces and through a directional feature of a curved surface placed above the membrane.

Abstract translation: 从液体中除去气泡并改善在微流体装置中通过膜的区域的均匀流体流动的方法和系统，包括减少，去除和/或防止多孔膜表面上的气泡。 示例性膜气泡捕集系统可以包括连接到气泡通道的流体通道，该气泡通道围绕用膜密封的开口。 气泡通道可以被配置成在液体中收集气泡，其通过浮力穿过膜并且通过位于膜上方的弯曲表面的方向特征。

公开(公告)号：US20110151432A1

公开(公告)日：2011-06-23

申请号：US12908829

申请日：2010-10-20

Applicant: Thomas M. Zappia ,  Brandon T. Johnson ,  Kate Christian ,  David Vogler ,  David Butz

Inventor： Thomas M. Zappia ,  Brandon T. Johnson ,  Kate Christian ,  David Vogler ,  David Butz

IPC: C12Q1/70 ,  G01N1/00 ,  B01D35/00 ,  G01N33/53 ,  C12M1/00 ,  G01N33/566 ,  A61B5/157

CPC classification number: G01N33/558 ,  A61B10/0045 ,  B01L3/502 ,  B01L2300/0636 ,  B01L2400/0478 ,  G01N33/54366 ,  Y10T436/25375

Abstract: Methods and systems to related to sample collection, assays, and fluid control and management, including methods and systems to implement hand-held portable assays, to activate an assay system, to collect and prepare samples, to capture antibodies, and to trap or capture gas bubbles. Methods and systems disclosed herein, and portions thereof, may be implemented alone and/or in various combinations with one another.

Abstract translation: 与样品收集，测定和流体控制和管理相关的方法和系统，包括实施手持式便携式测定的方法和系统，激活测定系统，收集和制备样品，捕获抗体，捕获或捕获 气泡。 本文公开的方法和系统及其部分可以单独实现和/或彼此以各种组合来实现。

公开(公告)号：US20070087317A1

公开(公告)日：2007-04-19

申请号：US11250684

申请日：2005-10-14

Applicant: Paul Taheri ,  David Butz

Inventor： Paul Taheri ,  David Butz

IPC: G09B3/00

CPC classification number: G09B5/00 ,  G09B7/00

Abstract: A method for instructing a student under the direction of a director allows the student to augment his or her core curriculum with tutorials relating to a non-core curriculum such as business administration. The method uses multiple modules in specific topical areas of study. The method may be environment specific so that the student can readily identify and incorporate the non-core curriculum into practice. The non-core curriculum is designed to be appropriate for the level at which the student has obtained. In that regard, the topical areas of study and the modules are organized to introduce concepts and skills at points in the core curriculum of the student that are appropriate to help facilitate maximum absorption. A reporting mechanism will provide the student and director with valuable information regarding the performance of the student.

Abstract translation: 指导学生在导演指导下的方法允许学生用与非核心课程（如工商管理）相关的教程来增加他或她的核心课程。 该方法在特定主题学习领域使用多个模块。 该方法可能是环境特定的，以便学生能够轻易地将非核心课程确定并纳入实践。 非核心课程旨在适应学生获得的水平。 在这方面，主要的学习领域和模块的组织方式是在学生的核心课程中引入概念和技能，以便帮助促进最大程度的吸收。 报告机制将为学生和导演提供关于学生表现的宝贵信息。

公开(公告)号：US5272083A

公开(公告)日：1993-12-21

申请号：US705767

申请日：1991-05-28

Applicant: David Butz ,  George Lyman ,  David Root ,  Gregory Mathus

Inventor： David Butz ,  George Lyman ,  David Root ,  Gregory Mathus

IPC: C12M3/00 ,  C12M3/06 ,  C12N5/00 ,  C12N5/06

CPC classification number: C12M47/02 ,  C12M23/00 ,  C12M23/12 ,  C12M25/04

Abstract: A tissue or cell growth device is described for placement within a well of a cluster dish. The device has a cell or tissue retention element detachably attached to a hanger. The hanger preferably has openings allowing access to the well without removal of the member and is capable of positioning the cell or tissue retention element a preselected distance relative to the hanger. Also described are various embodiments of the device having differently shaped hangers and the combination of the device and a cluster dish.

Abstract translation: 描述了组织或细胞生长装置用于放置在簇盘的孔内。 该装置具有可拆卸地附接到衣架的细胞或组织保持元件。 衣架优选地具有允许进入井的开口，而不移除构件，并且能够将电池或组织保持元件相对于衣架定位成预选的距离。 还描述了具有不同形状的悬挂器以及装置和簇盘的组合的装置的各种实施例。

公开(公告)号：US5139951A

公开(公告)日：1992-08-18

申请号：US595305

申请日：1990-10-10

Applicant: David Butz ,  George Lyman ,  David Root ,  Gregory Mathus

Inventor： David Butz ,  George Lyman ,  David Root ,  Gregory Mathus

IPC: C12M3/06

CPC classification number: C12M25/02 ,  C12M23/00 ,  C12M23/12

Abstract: A tissue or cell growth device is described for placement within a well of a cluster dish. The device has a cell or tissue retention element detachably attached to a hanger. The hanger preferably has openings allowing access to the well without removal of the member and is capable of positioning the cell or tissue retention element a preselected distance relative to the hanger. Also described are various embodiments of the device having differently shaped hangers and the combination of the device and a cluster dish.

Abstract translation: 描述了组织或细胞生长装置用于放置在簇盘的孔内。 该装置具有可拆卸地附接到衣架的细胞或组织保持元件。 衣架优选地具有允许进入井的开口，而不移除构件，并且能够将电池或组织保持元件相对于衣架定位成预选的距离。 还描述了具有不同形状的悬挂器以及装置和簇盘的组合的装置的各种实施例。