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公开(公告)号：US20130017547A1
公开(公告)日：2013-01-17
申请号：US13521423
申请日：2011-01-11
Applicant: Claudine Kieda , Maria Paprocka , Michele Mitterand , Nathalie Lamerant-Fayel , Henri-Jean Boulouis , Nadia Haddad , Martine Monteil
Inventor： Claudine Kieda , Maria Paprocka , Michele Mitterand , Nathalie Lamerant-Fayel , Henri-Jean Boulouis , Nadia Haddad , Martine Monteil
CPC classification number: C12N5/069 , G01N33/5064
Abstract: The present invention relates to isolated organ-specific feline endothelial cells. Specifically, the present invention relates to established organ-specific feline endothelial cells. The present invention also relates to organ-specific feline endothelial cells derived from micro- and macro-vascularisation. The present invention also relates to methods for screening molecules, for studying pathologies and for producing pathogens using same.
Abstract translation: 本发明涉及分离的器官特异性猫皮内皮细胞。 具体地说，本发明涉及建立的器官特异性猫内皮细胞。 本发明还涉及衍生自微血管和大血管的器官特异性猫皮内皮细胞。 本发明还涉及用于筛选分子的方法，用于研究病理学和使用其产生病原体。
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2.发明申请公开(公告)号：US20120003327A1
公开(公告)日：2012-01-05
申请号：US13033363
申请日：2011-02-23
Applicant: Yves Claude NICOLAU , Jean-Marie LEHN , Claudine KIEDA
Inventor： Yves Claude NICOLAU , Jean-Marie LEHN , Claudine KIEDA
IPC: A61K31/6615 , A61P35/00 , A61K33/24
CPC classification number: A61K31/6615 , A61K31/282 , A61K31/337 , A61K31/4745 , A61K31/513 , A61K31/665 , A61K31/7068 , A61K33/24 , A61K45/06 , A61K2300/00
Abstract: Inositol trisphosphate (ITPP) causes normalization of tumor vasculature and is a particularly effective cancer therapy when a second chemotherapeutic agent is administered following partial vascularization. ITPP also treats, alone or in combination, multi-drug resistant cancers. ITPP can also be used to reduce the amount of a second chemotherapeutic drug required for anticancer activity. In addition, ITPP enhances immune response and treats hyperproliferative disorders.
Abstract translation: 肌醇三磷酸（ITPP）导致肿瘤血管系统的正常化，并且当在部分血管形成后施用第二化学治疗剂时，是特别有效的癌症治疗。 ITPP也单独或组合治疗多重耐药性癌症。 ITPP也可用于减少抗癌活性所需的第二化疗药物的量。 此外，ITPP增强免疫反应并治疗过度增殖性疾病。
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3.发明授权Method of targeting melanocytes with a compound containing a fucose residue 失效用含有岩藻糖残基的化合物靶向黑素细胞的方法
公开(公告)号：US5332575A
公开(公告)日：1994-07-26
申请号：US861780
申请日：1992-04-02
Applicant: Gerard Redziniak , Dominique Cerdan , Claudine Kieda , Michel Monsigny
Inventor： Gerard Redziniak , Dominique Cerdan , Claudine Kieda , Michel Monsigny
CPC classification number: A61Q19/04 , A61K47/48815 , A61K8/14 , A61K8/60 , A61K9/1271 , A61Q19/02 , A61Q5/08 , Y10S514/844
Abstract: The invention concerns a method of binding a product to the membrane of a melanocyte by means of a ligand-receptor bond, which comprises using a product consisting of a basic structure coupled to at least one ligand consisting of an oside residue accessible to the membrane receptors, said oside residue being a fucose residue, notably an Alpha-L-fucose residue.
Abstract translation: 本发明涉及通过配体 - 受体键将产物与黑素细胞膜结合的方法，该方法包括使用由至少一种配体组成的产物，所述碱性结构与至少一种由膜受体可接近的残基组成的配体 所述残留物是岩藻糖残基，特别是α-L-岩藻糖残基。
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Patent Agency Ranking
公开(公告)号：US09631178B2
公开(公告)日：2017-04-25
申请号：US13521715
申请日：2011-01-11
Applicant: Claudine Kieda , Catherine Grillon , Nathalie Lamerant-Fayel , Maria Paprocka , Agnieszka Krawczenko , Danuta Goszyk-Dus
Inventor： Claudine Kieda , Catherine Grillon , Nathalie Lamerant-Fayel , Maria Paprocka , Agnieszka Krawczenko , Danuta Goszyk-Dus
CPC classification number: C12N5/0692 , G01N33/5064 , G01N33/5073
Abstract: The present invention relates to isolated human cells that are precursors of endothelial cells other than embryonic stem cells, to isolated murine cells that are precursors of endothelial cells, and to methods using same. In particular, the present invention relates to established cell lines of isolated human cells that are precursors of endothelial cells other than embryonic stem cells and established cell lines of isolated murine cells that are precursors of endothelial cells. The present invention can be used in particular in the medical and/or veterinary fields, in particular in the field of therapeutics and/or in the field of studies of cellular mechanisms.
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公开(公告)号：US09228173B2
公开(公告)日：2016-01-05
申请号：US13521423
申请日：2011-01-11
Applicant: Claudine Kieda , Maria Paprocka , Michele Mitterand , Nathalie Lamerant-Fayel , Henri-Jean Boulouis , Nadia Haddad , Martine Monteil
Inventor： Claudine Kieda , Maria Paprocka , Michele Mitterand , Nathalie Lamerant-Fayel , Henri-Jean Boulouis , Nadia Haddad , Martine Monteil
CPC classification number: C12N5/069 , G01N33/5064
Abstract: The present invention relates to isolated organ-specific feline endothelial cells. Specifically, the present invention relates to established organ-specific feline endothelial cells. The present invention also relates to organ-specific feline endothelial cells derived from micro- and macro-vascularisation. The present invention also relates to methods for screening molecules, for studying pathologies and for producing pathogens using same.
Abstract translation: 本发明涉及分离的器官特异性猫皮内皮细胞。 具体地说，本发明涉及建立的器官特异性猫内皮细胞。 本发明还涉及衍生自微血管和大血管的器官特异性猫皮内皮细胞。 本发明还涉及用于筛选分子的方法，用于研究病理学和使用其产生病原体。
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公开(公告)号：US5686103A
公开(公告)日：1997-11-11
申请号：US717976
申请日：1996-09-23
Applicant: Gerard Redziniak , Dominique Cerdan , Claudine Kieda , Michel Monsigny
Inventor： Gerard Redziniak , Dominique Cerdan , Claudine Kieda , Michel Monsigny
CPC classification number: A61Q19/04 , A61K47/48815 , A61K8/14 , A61K8/60 , A61K9/1271 , A61Q19/02 , A61Q5/08 , Y10S514/844
Abstract: The invention concerns a method of binding a product to the membrane of a melanocyte by means of a ligand-receptor bond, which comprises using a product consisting of a basic structure coupled to at least one ligand consisting of an oside residue accessible to the membrane receptors, said oside residue being a fucose residue, notably an Alpha-L-fucose residue.
Abstract translation: 本发明涉及通过配体 - 受体键将产物与黑素细胞膜结合的方法，该方法包括使用由至少一种配体组成的产物，所述碱性结构与至少一种由膜受体可接近的残基组成的配体 所述残留物是岩藻糖残基，特别是α-L-岩藻糖残基。
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7.发明授权Method of binding a product to the membrane of a keratinocyte by means of a ligand-receptor bond, method of preparing such a product, product obtained, cosmetic or pharmaceutical composition in which it is present and its method of preparation 失效通过配体 - 受体键将产物与角质形成细胞的膜结合的方法，制备这种产物的方法，获得的产物，其存在的化妆品或药物组合物及其制备方法
公开(公告)号：US5286629A
公开(公告)日：1994-02-15
申请号：US761809
申请日：1991-11-04
Applicant: Alain Denis , Claudine Kieda , Michel Monsigny , Pierre Perrier , Gerard Redziniak
Inventor： Alain Denis , Claudine Kieda , Michel Monsigny , Pierre Perrier , Gerard Redziniak
IPC: A61K8/00 , A61K8/04 , A61K8/14 , A61K8/60 , A61K8/64 , A61K8/73 , A61K9/127 , A61K9/51 , A61K47/36 , A61K47/42 , A61Q7/00 , A61Q19/00 , A61Q90/00 , A61K47/48
CPC classification number: A61Q19/08 , A61K8/0241 , A61K8/11 , A61K8/14 , A61K8/60 , A61K9/127 , A61K9/1271 , A61Q19/00 , A61Q7/00 , B82Y5/00 , A61K2800/413 , A61K2800/434 , A61K2800/57 , A61K2800/612 , A61K2800/654 , Y10S514/844
Abstract: The invention relates to products which are to be bound specifically to the membrane of a keratinocyte by means of a ligand-receptor bond.These products carry at least one ligand consisting of an oside residue selected from .alpha.-L-rhamnose, .alpha.-D-galactose and .alpha.-D-galactose-6-phosphate.By virtue of this specificity, it is possible to prepare cosmetic or pharmaceutical compositions having an improved efficacy in particular, for example for regeneration of the epidermis, for the treatment of psoriasis or for renewed hair growth.
Abstract translation: 本发明涉及通过配体 - 受体键特异性固定在角质形成细胞膜上的产品。 所述产物是至少一种配体，其由选自α-L-鼠李糖，α-D-半乳糖和α-D-半乳糖-6-磷酸的oside残基组成。 由于其具体特征，可以制备具有特别是提高的效率的化妆品或药物组合物，例如用于表皮再生，用于治疗牛皮癣和用于头发再生长。
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8.发明申请公开(公告)号：US20130040315A1
公开(公告)日：2013-02-14
申请号：US13521715
申请日：2011-01-11
Applicant: Claudine Kieda , Catherine Grillon , Nathalie Lamerant-Fayel , Maria Paprocka , Agnieszka Krawczenko , Danura Goszyk-Dus
Inventor： Claudine Kieda , Catherine Grillon , Nathalie Lamerant-Fayel , Maria Paprocka , Agnieszka Krawczenko , Danura Goszyk-Dus
CPC classification number: C12N5/0692 , G01N33/5064 , G01N33/5073
Abstract: The present invention relates to isolated human cells that are precursors of endothelial cells other than embryonic stem cells, to isolated murine cells that are precursors of endothelial cells, and to methods using same, In particular, the present invention relates to established cell lines of isolated human cells that are precursors of endothelial cells other than embryonic stem cells and established cell lines of isolated murine cells that are precursors of endothelial cells. The present invention can be used in particular in the medical and/or veterinary fields, in particular in the field of therapeutics and/or in the field of studies of cellular mechanisms.
Abstract translation: 本发明涉及作为除胚胎干细胞之外的内皮细胞的前体的分离的人细胞，以及作为内皮细胞的前体的分离的鼠细胞以及使用其的方法。特别地，本发明涉及已建立的分离的细胞系 作为胚胎干细胞以外的内皮细胞的前体的人细胞以及作为内皮细胞前体的分离的鼠细胞的确定的细胞系。 本发明特别可用于医学和/或兽医学领域，特别是在治疗学领域和/或在细胞机制研究领域。
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