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    Linker, impedance biochip, and method of quantitatively detecting target analyte in fluid sample using the biochip
    1.
    发明授权
    Linker, impedance biochip, and method of quantitatively detecting target analyte in fluid sample using the biochip 有权
    链接器，阻抗生物芯片和使用生物芯片定量检测流体样品中的目标分析物的方法

    公开(公告)号：US08663451B2

    公开(公告)日：2014-03-04

    申请号：US13161702

    申请日：2011-06-16

    申请人： Chih-Kung Lee ,  Adam Shih-Yuan Lee ,  Ching-Sung Chen ,  Ku-Ning Chang ,  Ying-Hua Chen ,  Bryan Yong-Jay Lee

    发明人： Chih-Kung Lee ,  Adam Shih-Yuan Lee ,  Ching-Sung Chen ,  Ku-Ning Chang ,  Ying-Hua Chen ,  Bryan Yong-Jay Lee

    IPC分类号： G01N27/327

    CPC分类号： C07D333/34 ,  C07D333/18 ,  C07D333/22 ,  C07D333/38 ,  C07D409/04 ,  C07D409/14 ,  G01N33/54353 ,  G01N33/5438

    摘要： The present invention provides a linker for joining an electrode and a capture probe on a biochip, and a biochip comprising the linker. The impedance baseline of the linker of the present invention is three orders lower than the conventional long chain thiol linker when adopting in a fadaraic impedance biochip construction. With lower impedance baseline, the device designed to measure the signal of the biochip of the present invention could be further simplied on the electrical circuit design and be made in lower cost, compacter size and get the potential to be used in point-of-care applications. The present invention also provides a method of quantitatively detecting a concentration of a target analyte in a fluid sample by adopting the biochip and the linker of present invention.

    摘要翻译： 本发明提供了用于将生物芯片上的电极和捕获探针连接的接头和包含接头的生物芯片。 本发明的接头的阻抗基线在采用制动阻抗生物芯片结构时比传统的长链硫醇连接体低三个数量级。 利用较低的阻抗基线，设计用于测量本发明的生物芯片的信号的器件可以进一步简化电路设计，并且可以以更低的成本，更大的尺寸制造并获得在点护理中使用的潜力 应用程序。 本发明还提供一种通过采用本发明的生物芯片和接头来定量检测流体样品中的目标分析物的浓度的方法。

    Paper lunch box
    3.
    发明授权
    Paper lunch box 失效
    纸饭盒

    公开(公告)号：US6092718A

    公开(公告)日：2000-07-25

    申请号：US477329

    申请日：2000-01-04

    申请人： Ching-Sung Chen ,  Shen-Pin Lai

    发明人： Ching-Sung Chen ,  Shen-Pin Lai

    IPC分类号： B65D5/4805 ,  B65D5/498 ,  B65D25/04

    CPC分类号： B65D5/48048 ,  B65D5/48022

    摘要： A paper lunch box includes a box body, at least one longitudinal partition member and at least one transverse partition members respectively installed in the box body to support the box body in shape and to separate the holding space of the box body into separated compartments, the box body being formed of a patterned cardboard folded up into a rectangular container having vertical peripheral walls of double-layer construction, the transverse and longitudinal partition members being formed of a respective patterned cardboard, each having a .andgate.-like cross section and reinforcing end flaps for mounting.

    摘要翻译： 纸餐盒包括箱体，至少一个纵向分隔构件和分别安装在箱体中的至少一个横向分隔构件，以支撑箱体的形状并将箱体的保持空间分离成分离的隔室， 盒体由图案化的纸板形成，折叠成具有双层结构的垂直周壁的矩形容器，横向和纵向分隔构件由相应的图案化纸板形成，每个具有“和”等截面和加强端板 用于安装。

    Structure bolt snap
    4.
    发明申请
    Structure bolt snap 审中-公开
    结构螺栓卡扣

    公开(公告)号：US20050138781A1

    公开(公告)日：2005-06-30

    申请号：US10745618

    申请日：2003-12-29

    申请人： Ching-Sung Chen

    发明人： Ching-Sung Chen

    IPC分类号： F16B45/04

    CPC分类号： F16B45/04 ,  Y10T24/45403

    摘要： An improved structure bolt snap wherein a check member is situated in the movable bolt of the bolt snap retaining body to provide for the open and closed states of the retaining body via the actuating member horizontal smooth section located in the movable bolt passage, the external threads at the outermost extremity of which are fastened to the check member inside the movable bolt. When the retaining body is closed, the actuating member is rotated until the check member fastened to the actuating member is exposed at the outer periphery of the retaining body bore, disabling the downward movement of the actuating member such that the retaining body is maintained in a closed state, thereby effectively ensuring safe closure and coupling.

    摘要翻译： 一种改进的结构螺栓卡扣，其中检查构件位于螺栓卡扣保持体的可移动螺栓中，以通过位于可移动螺栓通道中的致动构件水平平滑部分提供保持体的打开和关闭状态，外螺纹 其最外端紧固在活动螺栓内的止回件上。 当保持体关闭时，致动构件被旋转直到固定到致动构件的检查构件在保持体孔的外周处露出，使得致动构件的向下移动不致使保持体保持在 关闭状态，从而有效地确保安全闭合和联接。

    Structure bolt snap
    6.
    发明申请
    Structure bolt snap 审中-公开
    结构螺栓卡扣

    公开(公告)号：US20060085954A1

    公开(公告)日：2006-04-27

    申请号：US10984941

    申请日：2004-11-10

    申请人： Ching-Sung Chen

    发明人： Ching-Sung Chen

    IPC分类号： F16B45/04

    CPC分类号： F16B21/165 ,  F16B21/12 ,  F16B45/04 ,  Y10T24/4755

    摘要： An improved structure bolt snap in which a rounded annular groove is disposed around the bolt body of a retaining body between the protruding ring and the stop ring, a vertical hollow passage and two horizontal through-holes are fabricated in a swivel component, and the lowest end of the slide slot cut contiguously along the bore of the retaining body is of an arcuate shape. As such, after the rounded annular groove and the stop ring of the retaining body are admitted into the hollow passage of the swivel component, two pins are inserted into the through-holes and the rounded annular groove, thereby constrictively conjoining the retaining body and the swivel component to effectively prevent their separation. Additionally, since the lowest end of the slide slot in the retaining body is of an arcuate shape, it is capable of dispersing concentrated stress when pulled by an external force.

    摘要翻译： 一种改进的结构螺栓卡扣，其中在突出环和止动环之间的保持体的螺栓体周围设置圆形环形槽，在旋转部件中制造垂直中空通道和两个水平通孔，并且最低 沿着保持体的孔连续切割的滑槽的端部为弓形。 因此，在圆形环形槽和保持体的止动环进入旋转部件的中空通道之后，两个销插入到通孔和圆形环形槽中，从而将保持体和 旋转部件以有效地防止它们的分离。 此外，由于保持体中的滑槽的最下端具有弓形形状，所以当通过外力拉动时能够分散集中的应力。