NOVEL METHODS FOR MODULATING INFLAMMATORY AND/OR IMMUNE RESPONSES
    5.
    发明申请
    NOVEL METHODS FOR MODULATING INFLAMMATORY AND/OR IMMUNE RESPONSES 有权
    用于调节炎症和/或免疫应答的新方法

    公开(公告)号:US20100068180A1

    公开(公告)日:2010-03-18

    申请号:US12448903

    申请日:2008-01-11

    摘要: The invention is directed to novel methods for modulating inflammatory and/or immune responses. Such methods utilize compositions comprising extraembryonic cells (herein referred to as EE cells) including but not limited to extraembryonic HLA-G positive cells (herein referred to as EHP cells) and amnion-derived multipotent progenitor cells (herein referred to as AMP cells); compositions comprising expanded EE cell populations, and/or cell lysates and/or conditioned media derived therefrom, alone or in combination with each other and/or in combination with various extracellular matrices and/or devices and/or other suitable active agents.

    摘要翻译: 本发明涉及用于调节炎症和/或免疫应答的新方法。 这种方法利用包括但不限于胚胎外HLA-G阳性细胞(本文中称为EHP细胞)和羊膜来源的多潜能祖细胞(本文称为AMP细胞)的外胚细胞(本文称为EE细胞)的组合物; 包含扩增的EE细胞群体和/或细胞裂解物和/或由其衍生的条件培养基的组合物,彼此或彼此组合和/或与各种细胞外基质和/或装置和/或其它合适的活性剂组合。

    Amnion-derived cells, methods of making and uses thereof
    7.
    发明申请
    Amnion-derived cells, methods of making and uses thereof 有权
    羊膜来源的细胞,其制备方法和用途

    公开(公告)号:US20130071363A1

    公开(公告)日:2013-03-21

    申请号:US13644026

    申请日:2012-10-03

    IPC分类号: A61K35/50 C12N5/07

    摘要: The invention is directed to substantially purified amnion-derived cell populations, compositions comprising the substantially purified amnion-derived cell populations, and to methods of creating such substantially purified amnion-derived cell populations, as well as methods of use. The invention is further directed to antibodies, in particular, monoclonal antibodies, that bind to amnion-derived cells or, alternatively, to one or more amnion-derived cell surface protein markers. The invention is further directed to methods for producing the antibodies, methods for using the antibodies, and kits comprising the antibodies.

    摘要翻译: 本发明涉及基本上纯化的羊膜来源的细胞群,包含基本上纯化的羊膜来源的细胞群的组合物,以及产生这种基本上纯化的羊膜来源的细胞群的方法以及使用方法。 本发明还涉及结合羊膜来源的细胞或者另一种或多种羊膜来源的细胞表面蛋白质标记的抗体,特别是单克隆抗体。 本发明还涉及生产抗体的方法,使用抗体的方法和包含抗体的试剂盒。