公开(公告)号：US20240050421A1

公开(公告)日：2024-02-15

申请号：US18257273

申请日：2021-12-13

Applicant: Concentric Analgesics, Inc.

Inventor： Susan WOLLOWITZ ,  John F. DONOVAN

IPC: A61K31/445 ,  A61K9/19 ,  A61K47/12 ,  A61K47/26 ,  A61J1/14 ,  A61M5/19 ,  A61K45/06

CPC classification number: A61K31/445 ,  A61K9/19 ,  A61K47/12 ,  A61K47/26 ,  A61J1/1412 ,  A61M5/19 ,  A61K45/06

Abstract: Provided herein are pharmaceutical formulations comprising a transient receptor potential vanilloid 1 receptor (TRPV1) agonist, or a pharmaceutically acceptable salt thereof.

公开(公告)号：US11464767B2

公开(公告)日：2022-10-11

申请号：US17031729

申请日：2020-09-24

Applicant: Concentric Analgesics, Inc.

Inventor： John F. Donovan ,  Craig Husfeld

IPC: A61K31/445 ,  A61K45/06 ,  A61K31/165 ,  A61K31/137 ,  A61P29/00

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US20190055272A1

公开(公告)日：2019-02-21

申请号：US16078585

申请日：2017-02-22

Applicant: CONCENTRIC ANALGESICS, INC.

Inventor： Craig HUSFELD ,  Andrei W. KONRADI

IPC: C07F9/09 ,  C07D207/09 ,  C07F9/12 ,  C07F9/24 ,  C07F9/59 ,  C07D207/16 ,  C07D233/64 ,  C07C233/20 ,  C07C233/27 ,  C07C233/51 ,  C07C259/06 ,  C07C271/48 ,  C07C271/54 ,  C07C275/42 ,  C07C279/14 ,  C07C305/10 ,  C07C307/02 ,  C07C323/44 ,  C07C307/10 ,  C07C323/60 ,  C07C323/12 ,  A61P29/00

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US20230219901A1

公开(公告)日：2023-07-13

申请号：US18185291

申请日：2023-03-16

Applicant: Concentric Analgesics, Inc.

Inventor： John F. DONOVAN ,  Craig HUSFELD

IPC: C07D241/04 ,  C07D493/08

CPC classification number: C07D241/04 ,  C07D493/08

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US20220388970A1

公开(公告)日：2022-12-08

申请号：US17817184

申请日：2022-08-03

Applicant: CONCENTRIC ANALGESICS, INC.

Inventor： John F. DONOVAN ,  Craig HUSFELD

IPC: C07D241/04

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV 1) activity.

公开(公告)号：US10851123B2

公开(公告)日：2020-12-01

申请号：US16078585

申请日：2017-02-22

Applicant: CONCENTRIC ANALGESICS, INC.

Inventor： Craig Husfeld ,  Andrei W. Konradi

IPC: A61P29/00 ,  C07F9/09 ,  C07D233/64 ,  C07D207/16 ,  C07C259/06 ,  C07C271/48 ,  C07C271/54 ,  C07C275/42 ,  C07C279/14 ,  C07C305/10 ,  C07C307/02 ,  C07C307/10 ,  C07C323/12 ,  C07C323/44 ,  C07C323/60 ,  C07C233/20 ,  C07C233/27 ,  C07C233/51 ,  C07F9/12 ,  C07F9/24 ,  C07F9/59 ,  C07D211/26 ,  C07D213/81 ,  C07D211/28 ,  C07D295/185 ,  C07D207/09

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US20200299245A1

公开(公告)日：2020-09-24

申请号：US16895735

申请日：2020-06-08

Applicant: CONCENTRIC ANALGESICS, INC.

Inventor： John F. DONOVAN ,  Craig HUSFELD

IPC: C07D241/04

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US20190216787A1

公开(公告)日：2019-07-18

申请号：US16303082

申请日：2017-05-24

Applicant: CONCENTRIC ANALGESICS, INC.

Inventor： John F. DONOVAN ,  Craig HUSFELD

IPC: A61K31/445 ,  A61K45/06 ,  A61P29/00

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US20220112165A1

公开(公告)日：2022-04-14

申请号：US17556286

申请日：2021-12-20

Applicant: CONCENTRIC ANALGESICS, INC.

Inventor： John F. DONOVAN ,  Craig HUSFELD

IPC: C07D241/04

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.

公开(公告)号：US10717712B2

公开(公告)日：2020-07-21

申请号：US16522564

申请日：2019-07-25

Applicant: CONCENTRIC ANALGESICS, INC.

Inventor： John F. Donovan ,  Craig Husfeld

IPC: C07D241/04

Abstract: Described herein are compounds, pharmaceutical compositions and medicaments that include such compounds, and methods of using such compounds to modulate transient receptor potential vanilloid 1 receptor (TRPV1) activity.