公开(公告)号：US20240150825A1

公开(公告)日：2024-05-09

申请号：US18280588

申请日：2022-03-08

Applicant: Claret Bioscience, LLC

Inventor： Charles VASKE

IPC: C12Q1/6869 ,  G16B30/00

CPC classification number: C12Q1/6869 ,  G16B30/00

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library from single-stranded nucleic acid fragments. In some aspects, the technology relates to methods and compositions for analyzing a nucleic acid fragment length profile in a sample.

公开(公告)号：US20210054366A1

公开(公告)日：2021-02-25

申请号：US16961113

申请日：2019-01-11

Applicant: CLARET BIOSCIENCE, LLC

Inventor： Kelly M. HARKINS KINCAID ,  Joshua D. KAPP ,  Christopher J. TROLL

IPC: C12N15/10

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library. In some aspects, the technology relates to methods and compositions for analyzing ends of nucleic acid fragments.

公开(公告)号：US20250019693A1

公开(公告)日：2025-01-16

申请号：US18837787

申请日：2023-02-16

Applicant: Claret Bioscience, LLC

Inventor： Christopher J. TROLL

IPC: C12N15/10

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library. In some aspects, the technology relates to methods and compositions for reduction or elimination of adapter dimers in a nucleic acid library preparation.

公开(公告)号：US20240395358A1

公开(公告)日：2024-11-28

申请号：US18029550

申请日：2021-10-06

Applicant: Claret Bioscience, LLC

Inventor： Charles VASKE

IPC: G16B20/20 ,  G16B30/00

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for generating one or more genotypes for a sample. In some aspects, the technology relates to methods and compositions for generating one or more genotypes for a mixed sample.

公开(公告)号：US20230340609A1

公开(公告)日：2023-10-26

申请号：US18016957

申请日：2021-07-20

Applicant: Claret Bioscience, LLC

Inventor： Kelly M. HARKINS KINCAID ,  Charles VASKE

IPC: C12Q1/6886

CPC classification number: C12Q1/6886 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/154

Abstract: Provided in part are techniques for cancer detection, monitoring, and reporting from sequencing cell-free DNA in plasma samples. Such detection can be informed from patient-specific circulating tumor cell (CTC) somatic genomic, epigenetic, and/or transcriptomic modifications. These techniques can be used to aid treatment decision support, diagnosis, and/or prognosis of cancer.

公开(公告)号：US20230235320A1

公开(公告)日：2023-07-27

申请号：US18011271

申请日：2021-06-23

Applicant: CLARET BIOSCIENCE, LLC

Inventor： Christopher J. TROLL ,  Varsha RAO

IPC: C12N15/10 ,  C12Q1/6813 ,  C12Q1/6806

CPC classification number: C12N15/1093 ,  C12Q1/6813 ,  C12Q1/6806 ,  C12Q2600/16 ,  C12N2330/31

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library from single-stranded nucleic acid fragments.

公开(公告)号：US11584929B2

公开(公告)日：2023-02-21

申请号：US16961113

申请日：2019-01-11

Applicant: CLARET BIOSCIENCE, LLC

Inventor： Kelly M. Harkins Kincaid ,  Joshua D. Kapp ,  Christopher J. Troll

IPC: C12N15/10 ,  C12Q1/6855 ,  C12Q1/6869

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library. In some aspects, the technology relates to methods and compositions for analyzing ends of nucleic acid fragments.

公开(公告)号：US20230014607A1

公开(公告)日：2023-01-19

申请号：US17766031

申请日：2020-10-08

Applicant: CLARET BIOSCIENCE, LLC

Inventor： Richard Edward GREEN

IPC: C12Q1/6869 ,  G16B30/10 ,  G16B20/20

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for generating one or more genotypes.

公开(公告)号：US20230392141A1

公开(公告)日：2023-12-07

申请号：US18096192

申请日：2023-01-12

Applicant: CLARET BIOSCIENCE, LLC

Inventor： Kelly M. HARKINS KINCAID ,  Joshua D. KAPP ,  Christopher J. TROLL

IPC: C12N15/10 ,  C12Q1/6855

CPC classification number: C12N15/1065 ,  C12N15/1093 ,  C12Q1/6855 ,  C12Q1/6869

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library. In some aspects, the technology relates to methods and compositions for analyzing ends of nucleic acid fragments.

公开(公告)号：US20220348906A1

公开(公告)日：2022-11-03

申请号：US17440386

申请日：2020-04-02

Applicant: Claret Bioscience, LLC

Inventor： Kelly M. HARKINS KINCAID ,  Colin Patrick NAUGHTON ,  Varsha RAO ,  Christopher J. TROLL ,  Joshua D. KAPP

IPC: C12N15/10 ,  C12Q1/6806 ,  C12Q1/6869

Abstract: The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library from single-stranded nucleic acid fragments.