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公开(公告)号：US07281539B2
公开(公告)日：2007-10-16
申请号：US10474386
申请日：2002-04-12
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61J1/00 , A61M15/00 , A61M15/0003 , A61M15/0043 , A61M2202/064
摘要： A medicament container (10) is disclosed which comprises at least two compartments (21, 22). Each of the compartments (21, 22) is adapted to contain a dose of a medicament in powdered form and is provided with at least one opening (23) through which, in use, the medicament can be dispensed. The container (10) is preferably cylindrical in form, the diameter of the cylinder being greater than its depth such that the container (10) has the form of a squat drum.
摘要翻译： 公开了一种药物容器（10），其包括至少两个隔室（21,22）。 每个隔室（21,22）适于容纳一定剂量的粉末形式的药物，并且设置有至少一个开口（23），在使用中可以分配药物。 容器（10）的形状优选为圆柱形，圆柱体的直径大于其深度，使得容器（10）具有蹲下的形式。
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公开(公告)号：US07025057B2
公开(公告)日：2006-04-11
申请号：US10506909
申请日：2003-03-10
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0043 , A61M2202/064 , A61M2206/16
摘要： A system is disclosed for the administration of a powdered medicament by inhalation. The system comprises a container (20, 60, 120) containing a unit dose of medicament in powder form, the container (20, 60, 120) having at least one dispensing aperture (21), and a device (10, 50, 100) having a chamber (19, 56, 110) adapted to receive said container (20, 60, 120). The device (10, 50, 100) further comprises air inlet means (12, 12a, 13, 13a, 112, 113) by which air may be drawn into the chamber (19, 56, 110) and means (11, 111) by which air and entrained medicament may be drawn out of the chamber (19, 56, 110). The system is arranged such that the container (20, 60, 120), in use, is stationary within the chamber (19, 56, 110).
摘要翻译： 公开了通过吸入给药粉末药物的系统。 该系统包括容纳粉末形式的单位剂量的药物的容器（20,60,120），所述容器（20,60,120）具有至少一个分配孔（21）和装置（10,50,100） ）具有适于容纳所述容器（20,60,120）的腔室（19,56,110）。 装置（10,50,100）还包括空气入口装置（12,12a，13,13a，112,113），空气可以通过该空气入口装置被吸入室（19,56,110）中，并且装置 111），空气和夹带的药物可以从腔室（19,56,110）中抽出。 系统被布置成使得在使用中的容器（20,60,120）在腔室（19,56,110）内是静止的。
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公开(公告)号：US20090263408A1
公开(公告)日：2009-10-22
申请号：US12493601
申请日：2009-06-29
CPC分类号： A61J1/2093 , A61J1/2031 , A61J7/0046 , A61K47/02 , B65D51/2892
摘要： A medicament package (10,30) comprises a vessel (12,32) adapted to hold a quantity of a liquid vehicle. The vessel (12,32) has an opening formed therein, to which opening is bonded a deformable enclosure (18,38). A medicament container (20) that contains a unit dose of a medicament is received within the enclosure (18,38), such that by deformation of the enclosure (18,38) the container(20) may be dislodged from the enclosure (18,38) into the vessel (12,32), whereby the medicament may escape from the container (20) and mix with the liquid vehicle. The medicament contained within the medicament container (20) is most preferably in admixture with sodium chloride.
摘要翻译： 药物包装（10,30）包括适于容纳液体载体的容器（12,32）。 容器（12,32）具有形成在其中的开口，该开口与该可变形外壳（18,38）接合。 包含单位剂量的药物的药物容器（20）被容纳在外壳（18,38）内，使得通过外壳（18,38）的变形，容器（20）可以从外壳（18）移出 ，38）插入容器（12,32）中，由此药物可以从容器（20）逸出并与液体载体混合。 包含在药物容器（20）内的药物最优选与氯化钠混合。
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公开(公告)号：US5970974A
公开(公告)日：1999-10-26
申请号：US913247
申请日：1997-09-10
CPC分类号： B05B17/0607 , A61M11/005 , A61M11/007 , A61M15/0065 , A61M15/0085
摘要： The invention relates to an ultrasonic atomizer device (2) for a fluid (60), in particular a bronchospasmolytic agent, in which a propelling element (10) operable by an electronic circuit (6) to deliver the fluid to an atomization surface (28) that is also supplied with ultrasound waves from the electronic circuit (6) is provided in a housing (4), the propelling element (10) having a coupling member (32) which is meshing with a further coupling member (34) of a replaceable dosating unit (14) for transferring propelling power to the dosating unit (14) to effect a linear movement (68) of a piston (66) arranged in an ampoule (28) within the dosating unit (14). The invention also relates to a system comprising a device (2) as described and a dosating unit (14) inserted into that device (2).
摘要翻译： PCT No.PCT / EP96 / 01092 Sec。 371日期：1997年9月10日 102（e）1997年9月10日PCT PCT 1996年3月14日PCT公布。 公开号WO96 / 28205 PCT 日期1996年9月19日本发明涉及一种用于流体（60）的超声波雾化装置（2），特别是支气管痉挛溶解剂，其中推动元件（10）可由电子电路（6）操作以将流体输送到 还提供有来自电子电路（6）的超声波的雾化表面（28）设置在壳体（4）中，推进元件（10）具有联接构件（32），该联接构件与另一联接构件 （14）中的用于将推动力传递到所述剂量单元（14）以实现布置在所述剂量单元（14）内的安瓿（28）中的活塞（66）的线性运动（68）的可更换剂量单元（14） 。 本发明还涉及包括如上所述的装置（2）和插入该装置（2）中的剂量单元（14）的系统。
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公开(公告)号：US20090308388A1
公开(公告)日：2009-12-17
申请号：US12306467
申请日：2007-06-26
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0003 , A61M2202/064 , A61M2205/071
摘要： A dry powder inhaler (101) comprises an inhaler body (110), including an air passageway, and a medicament container (120). The medicament container (120) holds a dose of medicament and is provided with at least one dispensing aperture (123) through which the medicament may be drawn from the medicament container (120). The medicament container (120) is displaceable from a first position, in which the dispensing aperture (123) is occluded, to a second position, in which the dispensing aperture (123) is open and air is able to flow along the air passageway. When the medicament container (120) is in the first position, the air passageway is occluded by the medicament container (120).
摘要翻译： 干粉吸入器（101）包括包括空气通道的吸入器主体（110）和药物容器（120）。 药物容器（120）保持一定剂量的药物并且设置有至少一个分配孔（123），药物可以通过该分配孔从药物容器（120）中被拉出。 药物容器（120）可从分配孔（123）被封闭的第一位置移动到第二位置，在第二位置，分配孔（123）打开，空气能够沿着空气通道流动。 当药物容器（120）处于第一位置时，空气通道被药物容器（120）封闭。
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公开(公告)号：US06418926B1
公开(公告)日：2002-07-16
申请号：US09319754
申请日：1999-10-04
IPC分类号： A61M1500
CPC分类号： A61M15/0028 , A61J1/00 , A61M11/003 , A61M15/0008 , A61M15/0026 , A61M15/0033 , A61M2202/064 , A61M2206/16
摘要： A system for the administration of a powdered medicament by inhalation comprises a container (21) containing a unit dose of medicament in powder form, and a device (10) having a chamber (16) adapted to receive the container (21). The device (10) has air inlets (19, 20) by which air may be drawn into the chamber (16) and a mouthpiece (14) by which air and entrained medicament may be drawn out of the chamber (16). The chamber (16) is substantially circular or annular in form and, in use, the container (21) follows an orbital path within the chamber (16), medicament being dispensed from the container (21) through at least one opening in the container (21). Also described are novel forms of packaging for powdered medicaments which are particularly suitable for use in the system.
摘要翻译： 用于通过吸入给药粉末药物的系统包括容纳粉末形式的单位剂量的药物的容器（21），以及具有适于容纳容器（21）的腔室（16）的装置（10）。 装置（10）具有空气入口（19,20），空气可以通过空气入口（19,20）吸入腔室（16）和吸口（14），空气和夹带的药物可以通过该口件从腔室（16）中抽出。 腔室16的形状基本上为圆形或环形，并且在使用中容器（21）沿着腔室（16）内的轨道路径行进，药物通过容器（21）中的至少一个开口从容器（21）中分配 （21）。 还描述了特别适用于该系统的粉末药物的新型包装形式。
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公开(公告)号：US5787881A
公开(公告)日：1998-08-04
申请号：US789073
申请日：1997-02-03
CPC分类号： A61M15/0028 , A61M15/0031 , A61M2202/064 , A61M2206/16
摘要： A device for the administration of powdered inhalation medicament contained initially in a capsule having at least one aperture formed therein, comprising a swirl chamber (1) adapted to receive the medicament capsule; a mouthpiece (2) communicating with the swirl chamber (1) and separated therefrom by a grid (4); at least one air inlet (5) in tangential communication with the swirl chamber (1) whereby air can be drawn through the device via the mouthpiece (2) to cause a swirling air flow through the swirl chamber (1); and a cover member (7), having a continuous substantially planar inner surface, provided on the base of the swirl chamber (1) remote from the mouthpiece (2); said cover (7) being moveable between a first position in which the capsule can be inserted into the swirl chamber (1) and a second position in which the capsule is retained in the swirl chamber (1) and rotates upon air being drawn through the device, thereby dispensing the medicament contained therein.
摘要翻译： 一种用于施用粉末吸入药物的装置，其最初包含在其中形成有至少一个孔的胶囊中，包括适于接收药物胶囊的旋流室（1） 与所述涡流室（1）连通并由格栅（4）分离的接口（2）。 至少一个与所述涡流室（1）切向连通的空气入口（5），由此可以通过所述接口（2）将空气抽吸通过所述设备，以使涡旋空气流过所述涡流室（1）; 以及设置在所述旋转室（1）的远离所述接口（2）的基部上的具有连续的基本平坦的内表面的盖构件（7）。 所述盖（7）能够在所述胶囊能够插入到所述涡流室（1）中的第一位置和所述胶囊保持在所述旋转室（1）中的第二位置之间移动，并且在空气被吸入所述涡流室 从而分配其中所含的药物。
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公开(公告)号：US07562769B2
公开(公告)日：2009-07-21
申请号：US10548790
申请日：2004-03-11
CPC分类号： A61J1/2093 , A61J1/2031 , A61J7/0046 , A61K47/02 , B65D51/2892
摘要： A medicament package comprises a vessel adapted to hold a quantity of a liquid vehicle. The vessel has an opening formed therein. The opening engages a deformable enclosure which receives a medicament container that contains a unit dose of a medicament. The entire medicament package is sterile and is arranged such that by deformation of the enclosure the container may be dislodged from the enclosure into the vessel whereby the medicament may escape from the container and mix with the liquid vehicle. The medicament container is formed with one or more dispensing apertures through which the medicament may exit the container and/or liquid can enter the container. The medicament container may be formed as two or more components, the integrity of the container being maintained by its engagement with the enclosure and that integrity being lost once the container is released from the enclosure.
摘要翻译： 药物包装包括适于容纳液体载体的容器。 容器具有形成在其中的开口。 该开口接合可变形的外壳，其容纳包含单位剂量的药物的药物容器。 整个药物包装是无菌的并且被布置成使得通过外壳的变形，容器可以从外壳移出到容器中，由此药物可以从容器逸出并与液体载体混合。 药物容器形成有一个或多个分配孔，药物可以通过该分配孔离开容器和/或液体可以进入容器。 药物容器可以形成为两个或更多个部件，容器的完整性通过与壳体的接合来维持，并且一旦容器从外壳中释放就完全失去了。
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公开(公告)号：US07249600B2
公开(公告)日：2007-07-31
申请号：US10498331
申请日：2002-12-11
CPC分类号： A61M15/0028 , A61M2202/064
摘要： A medicament package comprises a medicament container (10) and a holder (20) within which the medicament container (10) is closely received. The holder (20) comprises a support (25) of a rigid material. The support (25) has an opening, to the periphery of which an enclosure (21) is bonded. The medicament container (10) is closely received within the enclosure (21) such that the material of the enclosure (21) seals openings formed in the container (10). The container (10) can be dispensed from the package into a delivery device by pressure applied to the enclosure (21).
摘要翻译： 药物包装包括药物容器（10）和药剂容器（10）紧密接收在其中的保持器（20）。 保持器（20）包括刚性材料的支撑件（25）。 所述支撑件（25）具有开口，所述支架（25）的外围与外壳（21）结合。 药物容器（10）紧密地容纳在外壳（21）内，使得外壳（21）的材料密封形成在容器（10）中的开口。 容器（10）可以通过施加到外壳（21）上的压力从包装分配到输送装置中。
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