-
公开(公告)号：US20060100191A1
公开(公告)日：2006-05-11
申请号：US10531495
申请日：2003-10-14
IPC分类号： A61K31/5377 , A61K31/454 , A61K31/4025 , A61K31/401 , C07D413/02 , C07D403/02
CPC分类号： C07D405/12 , C07D207/20 , C07D401/12 , C07D401/14 , C07D403/12
摘要： The present invention relates to dihydropyrrole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention is also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
-
公开(公告)号：US20050119484A1
公开(公告)日：2005-06-02
申请号：US10506702
申请日：2003-03-04
申请人： Michael Breslin , Paul Coleman , Christopher Cox , J. christopher Culberson , George Hartman , Brenda Mariano , Maricel Torrent
发明人： Michael Breslin , Paul Coleman , Christopher Cox , J. christopher Culberson , George Hartman , Brenda Mariano , Maricel Torrent
IPC分类号： A61K31/415 , A61K31/4155 , A61K31/4178 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K45/00 , A61P35/00 , C07D231/06 , C07D231/14 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D405/12 , C07D413/04 , C07D417/04 , C07D43/02
CPC分类号： C07D401/04 , C04B35/632 , C07D231/06 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D405/12 , C07D413/04 , C07D417/04
摘要： The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
摘要翻译： 本发明涉及可用于治疗细胞增殖性疾病，治疗与KSP驱动蛋白活性相关的疾病和用于抑制KSP驱动蛋白的二氢吡唑化合物。 本发明还涉及包含这些化合物的组合物，以及使用它们治疗哺乳动物癌症的方法。
-
搜索结果
2 条记录 (耗时 0.025 秒)
