Abstract:
The invention relates to novel indole derivatives of the general formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
Abstract:
The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
Abstract:
The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
Abstract:
The invention relates to novel pyridine derivatives of formula 1, to their preparation and to their use as medicaments, in particular for treating tumors
Abstract:
The side effect of decrease in body weight caused by the alkylphosphocholines such as miltefosine can be antagonized by certain acetylcholine receptor antagonists such as domperidone and pimozide. The combination of alkylphosphocholine plus the antagonist does not have any effect on the anti-tumor action of the alkylphosphocholine. The combination also caused no new side effects in the animals.
Abstract:
A method for measuring the position, attitude and/or positional or attitudinal change of a fixed body in space, such as the lower jaw of a patient in a dental examination, utilizes signals obtained from a number of magnetic flux pickup blocks arranged at a distance from a magnetic field generator, the magnetic field generator being disposed on or a short distance from the fixed body and generating a defined irregular field. The pickup blocks detect the field flux, or the field flux alteration, during a measurement. In order to eliminate interference signals occurring in the region of the measuring system the signals from all of the pickup blocks are first added and the aggregate interference signals formed therefrom are respectively subtracted from the individual pickup block signals.
Abstract:
The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
Abstract:
Compounds of the general formula: ##STR1## wherein the radicals R.sub.1 and R.sub.2 are the same or different and represent hydrogen or C.sub.1 -C.sub.6 -alkyl, the radicals R.sub.3 and R.sub.4 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 -alkyl, hydroxy, C.sub.1 -C.sub.6 -alkoxy, C.sub.2 -C.sub.6 -alkanoyloxy, halogen or C.sub.2 -C.sub.6 -alkanoyl, X is oxygen, sulphur or the group --NR.sub.5 and R.sub.5 is hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkanoyl or benzoyl, m and n in each case may represent the integers 1, 2 or 3 and the phenyl radical A is unsubsituted or is substituted by halogen, nitro, C.sub.1 -C.sub.6 -alkyl, trifluoromethyl, C.sub.3 -C.sub.7 -cycloalkyl, hydroxy, C.sub.1 -C.sub.6 -alkoxy, C.sub.2 -C.sub.6 -alkanoyloxy, amino, C.sub.1 -C.sub.6 -alkylamino, di-C.sub.1 -C.sub.6 -alkylamino, C.sub.2 -C.sub.6 -alkanoylamino, CN, carboxy, C.sub.1 -C.sub.6 -alkoxycarbonyl, phenyl, C.sub.1 -C.sub.6 -alkylphenyl or trifluoromethylphenyl, their pyridine-N-oxides and physiologically acceptable salts thereof, processes for their preparation and medicines containing such compounds as active ingredients.
Abstract:
A recognition system is provided for tools, such as drill bits and milling bits, which are insertable into dental treatment instruments, each of the tools having an optimum speed at which the tool must be rotated for effective treatment. In the recognition system, each tool is provided with a code corresponding to the speed or speed graduation necessary to effectively use the tool. The system also includes a reader which reads the code on each tool, and generates identifying signals in accordance with the code, which are supplied to an evaluation logic. The logic converts the signal from the reader into control signals for the drive motor used to operate the tool, as well as indicator signals for visually displaying information relating to the tool currently in use.