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1.发明授权公开(公告)号：US09139731B2
公开(公告)日：2015-09-22
申请号：US12140501
申请日：2008-06-17
Applicant: Arif Ali Baig , Robert Vincent Faller , George Endel Deckner
Inventor： Arif Ali Baig , Robert Vincent Faller , George Endel Deckner
IPC: A61K6/00 , C08L71/02 , A61K8/19 , A61K8/21 , A61K8/24 , A61K8/55 , A61K8/81 , A61Q11/00 , C08G65/335
CPC classification number: A61K8/55 , A61K6/0067 , A61K8/19 , A61K8/21 , A61K8/24 , A61K8/416 , A61K8/4926 , A61K8/556 , A61K8/81 , A61K8/8147 , A61Q11/00 , C08G65/3355 , C08L71/02 , A61K6/0017 , C08L33/08 , C08L33/10
Abstract: Disclosed are oral care compositions comprising selected surface-active organophosphate compounds and methods of use to provide protection of teeth from erosion caused by the action of chemicals, such as harsh abrasives and acids. The surface-active organophosphate compounds are substantive to teeth, the phosphate groups binding the calcium in teeth and thus preventing loss of calcium from dissolution when contacted with acids. The organophosphate compound may also deposit a protective surface coating that prevents contact of teeth with erosive challenges. Selected organophosphate compounds contain one or more phosphate groups and are combined in the oral care composition with one or more of a fluoride ion agent, an antimicrobial agent preferably selected from quaternary ammonium compounds and polyvalent metal salts, an anticalculus agent and additional surfactant, to provide benefits including superior anti-erosion, anticaries, antiplaque and anti-staining as demonstrated by enhanced fluoride uptake, remineralization, resistance to acid demineralization and antimicrobial activities, resulting in improved overall tooth health, structural integrity and appearance.
Abstract translation: 公开了包含选择的表面活性有机磷酸酯化合物的口腔护理组合物和用于保护牙齿免受化学物质（例如刺激性磨料和酸）的作用所引起的侵蚀的方法。 表面活性有机磷酸酯化合物对牙齿是实质的，磷酸基团结合牙齿中的钙，从而防止当与酸接触时钙的溶解丧失。 有机磷酸盐化合物还可以沉积防止牙齿与侵蚀性挑战接触的保护性表面涂层。 所选的有机磷酸酯化合物含有一个或多个磷酸酯基，并且在口腔护理组合物中与一种或多种氟离子剂，优选选自季铵化合物和多价金属盐的抗微生物剂，抗结石剂和另外的表面活性剂组合，以提供 通过增强氟化物吸收，再矿化，抗酸脱矿质和抗微生物活性所证明的优点，包括优异的抗侵蚀，防褪色，抗菌斑和抗染色，从而改善整体牙齿健康状况，结构完整性和外观。
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公开(公告)号：US09005585B2
公开(公告)日：2015-04-14
申请号：US11904692
申请日：2007-09-28
Applicant: George Endel Deckner , Arif Ali Baig , Michael Jude LeBlanc
Inventor： George Endel Deckner , Arif Ali Baig , Michael Jude LeBlanc
CPC classification number: A61K8/042 , A61K8/046 , A61K8/19 , A61K8/21 , A61K8/22 , A61K8/24 , A61K8/25 , A61K8/29 , A61K8/342 , A61K8/345 , A61K8/38 , A61K8/44 , A61K8/442 , A61K8/463 , A61K8/466 , A61K8/49 , A61K8/4926 , A61K8/553 , A61K8/69 , A61K8/73 , A61K8/731 , A61K2800/28 , A61K2800/48 , A61K2800/59 , A61K2800/592 , A61K2800/5922 , A61K2800/92 , A61Q11/00
Abstract: The present invention is directed to an oral composition containing a gel network phase comprising: (i) one or more fatty amphiphiles, (ii) one or more surfactants, and (iii) one or more solvents; and an oral carrier phase. In certain embodiments, the gel network is used to structure the oral composition. The present invention is also directed to a method of forming an oral composition containing a gel network.
Abstract translation: 本发明涉及含有凝胶网状相的口腔组合物，其包含：（i）一种或多种脂肪两亲物，（ii）一种或多种表面活性剂，和（iii）一种或多种溶剂; 和口服载体相。 在某些实施方案中，凝胶网络用于构建口腔组合物。 本发明还涉及形成含有凝胶网络的口腔组合物的方法。
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公开(公告)号：US08551457B2
公开(公告)日：2013-10-08
申请号：US13463149
申请日：2012-05-03
Applicant: George Endel Deckner , Arif Ali Baig , Iain Allan Hughes , Eva Schneiderman , Lawrence Edward Dolan , Michael Jude Leblanc
Inventor： George Endel Deckner , Arif Ali Baig , Iain Allan Hughes , Eva Schneiderman , Lawrence Edward Dolan , Michael Jude Leblanc
CPC classification number: A61K8/25 , A61K8/922 , A61K2800/28 , A61Q11/00
Abstract: An oral care composition comprising fused silica, wherein at least 95% of the fused silica particles are spherical.
Abstract translation: 一种包含熔融二氧化硅的口腔护理组合物，其中至少95％的熔融二氧化硅颗粒是球形的。
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公开(公告)号：US08221726B2
公开(公告)日：2012-07-17
申请号：US12625098
申请日：2009-11-24
Applicant: George Endel Deckner , Arif Ali Baig , John Christian Haught , Iain Allan Hughes
Inventor： George Endel Deckner , Arif Ali Baig , John Christian Haught , Iain Allan Hughes
CPC classification number: A61Q11/00 , A61K8/25 , A61K8/922 , A61K2800/28 , Y10T428/2982
Abstract: An oral care composition comprising a fused silica abrasive, wherein the fused silica has a median particle size of from about 0.25 micron to about 5.0 microns.
Abstract translation: 一种包含熔融石英磨料的口腔护理组合物，其中所述熔融二氧化硅具有约0.25微米至约5.0微米的中值粒度。
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公开(公告)号：US08221723B2
公开(公告)日：2012-07-17
申请号：US12624659
申请日：2009-11-24
Applicant: George Endel Deckner , Arif Ali Baig , Iain Allan Hughes
Inventor： George Endel Deckner , Arif Ali Baig , Iain Allan Hughes
CPC classification number: A61Q11/00 , A61K8/25 , A61K8/922 , A61K2800/28 , Y10T428/2982
Abstract: An oral care composition comprising an abrasive combination of a fused silica abrasive and other abrasive selected from the group consisting of precipitated silica, calcium carbonate, rice hull silica, silica gels, aluminas, aluminium silicates, water-insoluble phosphates including orthophosphates, polymetaphosphates, pyrophosphates, other inorganic particulates, and mixtures thereof.
Abstract translation: 一种口腔护理组合物，其包含熔融二氧化硅磨料和选自沉淀二氧化硅，碳酸钙，稻壳二氧化硅，硅胶，氧化铝，硅酸铝，包括正磷酸盐在内的水不溶性磷酸盐，聚偏磷酸盐，焦磷酸盐 ，其它无机颗粒，及其混合物。
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Patent Agency Ranking
公开(公告)号：US08211408B2
公开(公告)日：2012-07-03
申请号：US12624812
申请日：2009-11-24
Applicant: Arif Ali Baig , George Endel Deckner , Iain Allan Hughes
Inventor： Arif Ali Baig , George Endel Deckner , Iain Allan Hughes
CPC classification number: A61Q11/00 , A61K8/25 , A61K8/922 , A61K2800/28 , Y10T428/2982
Abstract: An oral care composition comprising a fused silica abrasive and a fluoride source. The oral care composition may have a lower pH to aid in fluoride and/or active stability.
Abstract translation: 一种包含熔融二氧化硅研磨剂和氟化物源的口腔护理组合物。 口腔护理组合物可具有较低的pH以有助于氟化物和/或主动稳定性。
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7.发明授权公开(公告)号：US08211407B2
公开(公告)日：2012-07-03
申请号：US12624787
申请日：2009-11-24
Applicant: George Endel Deckner , Arif Ali Baig , Iain Allan Hughes
Inventor： George Endel Deckner , Arif Ali Baig , Iain Allan Hughes
CPC classification number: A61Q11/00 , A61K8/25 , A61K8/922 , A61K2800/28 , Y10T428/2982
Abstract: A method of making an oral care composition comprising the addition of a fused silica slurry.
Abstract translation: 一种制备口腔护理组合物的方法，包括加入熔融二氧化硅浆液。
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公开(公告)号：US20110104219A1
公开(公告)日：2011-05-05
申请号：US12911112
申请日：2010-10-25
Applicant: Jayanth Rajaiah , Arif Ali Baig , Robert Scott Leonard , Elizabeth Anne Wilder , Franco Silva Medeiros , Luisa Navarro Cerda , Steven Daryl Smith
Inventor： Jayanth Rajaiah , Arif Ali Baig , Robert Scott Leonard , Elizabeth Anne Wilder , Franco Silva Medeiros , Luisa Navarro Cerda , Steven Daryl Smith
IPC: A61K8/00 , A61K9/00 , A61P29/00 , A61P31/10 , A61P23/00 , A61P31/12 , A61P39/06 , A61P3/02 , A61P31/00 , A61Q11/02
CPC classification number: A61Q11/02 , A61K8/31 , A61K8/92 , A61K2800/31
Abstract: A denture care composition comprising one or more denture care actives and one or more water insoluble carriers, wherein the composition is bioerodible, not a denture adhesive, and substantially free of polybutene with a molecular weight of about 300 to about 3000 when the composition is not an article, and is applied to dentures.
Abstract translation: 一种义齿护理组合物，其包含一种或多种义齿护理活性物质和一种或多种水不溶性载体，其中所述组合物是可生物腐蚀的，而不是义齿粘合剂，并且当组合物不是时，基本上不含分子量为约300至约3000的聚丁烯 一篇文章，并适用于假牙。
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公开(公告)号：US20100135929A1
公开(公告)日：2010-06-03
申请号：US12624560
申请日：2009-11-24
Applicant: George Endel Deckner , Michael Jude LeBlanc , Lawrence Edward Dolan , Arif Ali Baig , Iain Allan Hughes
Inventor： George Endel Deckner , Michael Jude LeBlanc , Lawrence Edward Dolan , Arif Ali Baig , Iain Allan Hughes
CPC classification number: A61Q11/00 , A61K8/25 , A61K8/922 , A61K2800/28 , Y10T428/2982
Abstract: An oral care composition comprising a fused silica abrasive and a gel network.
Abstract translation: 一种包含熔融二氧化硅磨料和凝胶网络的口腔护理组合物。
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公开(公告)号：US20100135922A1
公开(公告)日：2010-06-03
申请号：US12624703
申请日：2009-11-24
Applicant: George Endel Deckner , Arif Ali Baig , Iain Allan Hughes
Inventor： George Endel Deckner , Arif Ali Baig , Iain Allan Hughes
CPC classification number: A61Q11/00 , A61K8/25 , A61K8/922 , A61K2800/28 , Y10T428/2982
Abstract: An oral care composition comprising fused silica, wherein at least 25% of the fused silica particles are spherical.
Abstract translation: 一种包含熔融二氧化硅的口腔护理组合物，其中至少25％的熔融二氧化硅颗粒是球形的。
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