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公开(公告)号：US20210283253A1
公开(公告)日：2021-09-16
申请号：US16837858
申请日：2018-10-01
Applicant: Aridis Pharmaceuticals, Inc.
Inventor： Vu Truong-Le
IPC: A61K39/40 , C07K16/12 , A61K31/496 , A61K38/12 , A61K31/546 , A61K31/427
Abstract: A combination of an antibody and other therapeutic that work together in vivo against a pathogenic microbe. The combination can include the antibody with an antibiotic, and/or a therapeutic against a disease. The combination can attack the pathogenic microbe with an efficiency more than either of the components alone, with a synergistic effect, or an effect moderated by one or more modes of action not existing with administration of either the antibody or therapeutic alone.
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公开(公告)号：US10603373B2
公开(公告)日：2020-03-31
申请号：US16124648
申请日：2018-09-07
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: C07K16/12 , C07K14/22 , C07K14/21 , A61K39/104 , A61K39/00
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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公开(公告)号：US20180214533A1
公开(公告)日：2018-08-02
申请号：US15896791
申请日：2018-02-14
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: A61K39/104 , C07K16/12 , C07K14/22 , C07K14/21 , A61K39/00
CPC classification number: A61K39/1045 , A61K39/104 , A61K2039/55555 , C07K14/212 , C07K14/22 , C07K16/1217
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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公开(公告)号：US10603372B2
公开(公告)日：2020-03-31
申请号：US15895511
申请日：2018-02-13
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: A61K39/104 , C07K14/21 , C07K14/22 , C07K16/12 , A61K39/00
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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公开(公告)号：US20200016258A1
公开(公告)日：2020-01-16
申请号：US16582413
申请日：2019-09-25
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: A61K39/104 , C07K14/21 , C07K16/12 , C07K14/22
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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Patent Agency Ranking
公开(公告)号：US10098942B2
公开(公告)日：2018-10-16
申请号：US15896711
申请日：2018-02-14
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: A61K39/104 , C07K14/21 , C07K14/22 , C07K16/12 , A61K39/00
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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公开(公告)号：US20240141385A1
公开(公告)日：2024-05-02
申请号：US17811414
申请日：2022-10-27
Applicant: Aridis Pharmaceuticals, Inc.
Inventor： Kathy Ngo , Jennifer Woo , Binh Pham , Vu Truong-Le
CPC classification number: C12N15/907 , C07K16/00 , C12N9/22 , C12N15/11 , C12N15/111 , C12N15/86 , C07K2317/14 , C12N2310/20 , C12N2750/14143 , C12N2800/30 , C12N2800/80
Abstract: This invention provides methods and systems for enhancement of protein production from mammalian cell lines in a drug inducible manner. The methods described herein can be used to generate a protein production cell line wherein the gene coding the protein product of interest is inserted into specific safe harbor loci (SHL) within the cell's genome and the gene copy number is induced to amplify by the use of an antibiotic inducer. The method enables for the conditional activation of the drug inducible transposase. The drug inducible gene amplification method described herein effectively functions as a molecular dial: combining drug-inducible homologous recombination and conditional gene activation to fine-tune gene amplification in mammalian systems.
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公开(公告)号：US10682404B2
公开(公告)日：2020-06-16
申请号：US16582413
申请日：2019-09-25
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: A61K39/104 , C07K14/21 , C07K14/22 , C07K16/12 , A61K39/00
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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公开(公告)号：US20190000955A1
公开(公告)日：2019-01-03
申请号：US16124648
申请日：2018-09-07
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: A61K39/104 , C07K14/22 , C07K16/12 , C07K14/21
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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公开(公告)号：US10111942B2
公开(公告)日：2018-10-30
申请号：US15896791
申请日：2018-02-14
Applicant: Aridis Pharmaceuticals Inc.
Inventor： Simon Urwyler , Markus Haake , Michael Rudolf
IPC: A61K39/104 , C07K14/21 , C07K14/22 , C07K16/12 , A61K39/00
Abstract: The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
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