公开(公告)号：USRE39794E1

公开(公告)日：2007-08-21

申请号：US11229446

申请日：2000-10-04

申请人： David Mark Sutton ,  Andrew George Hiles ,  Adrian Francis Backes

发明人： David Mark Sutton ,  Andrew George Hiles ,  Adrian Francis Backes

IPC分类号： C07D307/36 ,  C07D307/02 ,  C07D307/26 ,  C07C29/132

CPC分类号： C07D315/00 ,  C07C29/149 ,  C07C51/215 ,  C07C51/313 ,  C07C51/573 ,  C07D307/08 ,  C07C31/207 ,  C07C57/145

摘要： A process is described for the co-production of maleic anhydride and at least one C4 compound selected from butane-1,4-diol, γ-butyrolactone, and tetrahydrofuran in which maleic anhydride is produced by partial oxidation of a hydrocarbon feedstock selected from C4 hydrocarbons and benzene to yield a vaporous reaction effluent stream comprising maleic anhydride, water, unconverted hydrocarbon feedstock, and carbon oxides. A part of the maleic anhydride present in the vaporous reaction effluent stream is condensed to form a crude maleic anhydride stream and leave a residual vaporous stream containing residual amounts of maleic anhydride. Further maleic anhydride is absorbed from the residual vaporous stream by absorption in an organic solvent, water or an aqueous solution. Maleic anhydride is then recovered from the loaded liquid absorptions medium. Said at least one C4 compound is produced by hydrogenation of a C4+ hydrogenation feedstock selected from maleic anhydride, maleic acid, dialkyl maleates, and mixtures of two or more thereof. The process is characterised in that material of the crude maleic anhydride stream is used as the C4+ hydrogenation feedstock or is used to prepare the C4+ hydrogenation feedstock.

摘要翻译： 描述了共同生产马来酸酐和选自丁烷-1,4-二醇，γ-丁内酯和四氢呋喃中的至少一种C 4 H 4化合物的方法，其中马来酸酐由部分 选择C 4烃和苯的烃原料的氧化，得到包含马来酸酐，水，未转化的烃原料和碳氧化物的气态反应流出物流。 存在于气态反应流出物流中的马来酸酐的一部分被冷凝以形成粗马来酸酐流，并留下含有残留量马来酸酐的残余蒸气流。 另外的马来酸酐通过在有机溶剂，水或水溶液中的吸收从残余蒸气流吸收。 然后从负载的液体吸收介质中回收马来酸酐。 所述至少一种C 4 H 4化合物是通过氢化选自马来酸酐，马来酸，马来酸二烷基酯和其两种或多种的混合物的C 4+ 。 该方法的特征在于将粗制马来酸酐物流的材料用作C 4++氢化原料，或用于制备C 4++氢化原料。

公开(公告)号：US6100410A

公开(公告)日：2000-08-08

申请号：US180769

申请日：1998-11-12

申请人： Michael William Marshall Tuck ,  Michael Anthony Wood ,  Andrew George Hiles

发明人： Michael William Marshall Tuck ,  Michael Anthony Wood ,  Andrew George Hiles

IPC分类号： C07B61/00 ,  C07C29/149 ,  C07C29/17 ,  C07C31/20 ,  C07C33/035 ,  C07C67/08 ,  C07C69/60 ,  C07D307/08 ,  C07D307/33 ,  C07D315/00 ,  C07C27/06 ,  C07C29/136

CPC分类号： C07D307/33 ,  C07C29/149 ,  C07C29/177 ,  C07D307/08 ,  C07D315/00

摘要： A process for the production of at least one C.sub.4 compound selected from butane-1,4-diol, .gamma.-butyrolactone and tetrahydrofuran comprises contacting a vaporous stream containing maleic anhydride vapour, water vapour, and carbon oxides in an absorption zone with a high boiling organic solvent thereby to form a solution of maleic anhydride in the high boiling organic solvent. Maleic anhydride in this solution is reacted under esterification conditions in an esterification zone with a C.sub.1 to C.sub.4 alkanol to form a solution of the corresponding di-(C.sub.1 to C.sub.4 alkyl) maleate in the high boiling solvent. This solution of the di-(C.sub.1 to C.sub.4 alkyl) maleate in the high boiling solvent is contacted with a gaseous stream containing hydrogen thereby to strip di-(C.sub.1 to C.sub.4 alkyl) maleate therefrom and to form a vaporous stream comprising hydrogen and di-(C.sub.1 to C.sub.4 alkyl) maleate. Material of this vaporous stream is contacted in a hydrogenation zone under ester hydrogenation conditions in the presence of a heterogeneous ester hydrogenation catalyst thereby to convert di-(C.sub.1 to C.sub.4 alkyl) maleate to at least one C.sub.4 compound selected from butane-1,4-diol, .gamma.-butyrolactone and tetrahydrofuran which is recovered from the hydrogenation zone in the resulting product stream. The high boiling solvent has a boiling point at atmospheric pressure that is at least about 30.degree. C. higher than that of the di-(C.sub.1 to C.sub.4 alkyl) maleate.

摘要翻译： PCT No.PCT / GB97 / 01285 Sec。 371日期：1998年11月12日 102（e）1998年11月12日日期PCT提交1997年5月12日PCT公布。 公开号WO97 / 43242 日期1997年11月20日制备选自丁烷-1,4-二醇，γ-丁内酯和四氢呋喃中的至少一种C 4化合物的方法包括使含有马来酸酐蒸气，水蒸汽和碳氧化物的蒸汽流在吸收 区域，由此形成马来酸酐在高沸点有机溶剂中的溶液。 该溶液中的马来酸酐在酯化条件下在酯化区与C1至C4链烷醇反应，以在高沸点溶剂中形成相应的二（C1至C4烷基）马来酸酯的溶液。 马来酸二（C1-C4烷基）酯在高沸点溶剂中的溶液与含有氢气的气流接触，从而从其中剥离二（C1至C4烷基）马来酸酯，并形成含有氢和二 - （C1-C4烷基）马来酸酯。 在异构酯加氢催化剂存在下，在氢化反应条件下，在氢化反应区中使该气态物质接触，从而将马来酸二 - （C 1 -C 4烷基）酯转化为至少一种选自丁烷-1,4- 二醇，γ-丁内酯和四氢呋喃，其从所得产物流中的氢化区回收。 高沸点溶剂的沸点在大气压下至少比二（C1-C4烷基）马来酸酯高约30℃。

公开(公告)号：US08569550B2

公开(公告)日：2013-10-29

申请号：US13061904

申请日：2010-03-30

申请人： Donald Hugh McKinley ,  Andrew George Hiles ,  Rikard Umberto Andersson ,  John Richard Hensman

发明人： Donald Hugh McKinley ,  Andrew George Hiles ,  Rikard Umberto Andersson ,  John Richard Hensman

IPC分类号： C07C29/149 ,  C07C27/04

CPC分类号： C07C29/149 ,  Y02P20/132 ,  C07C31/125

摘要： A process for the co-production of a stream of a fatty alcohol having first carbon chain lengths and a stream of a fatty alcohol having a second carbon chain lengths, said second carbon chain lengths being longer than said first carbon chain lengths, said process comprising the steps of: (a) supplying a stream comprising lower alkyl esters of fatty acids having chain lengths comprising the first and second chain lengths to a first vaporization zone and contacting said stream with an amount of hydrogen recycled from step (i) which is sufficient to vaporize the lower alkyl esters of the fatty acids having the first carbon chain lengths into the hydrogen; (b) supplying the hydrogen and the vaporized lower alkyl esters of fatty acids having the first carbon chain lengths to a first reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having first carbon chain lengths; (c) recovering from the first reaction zone an alcohol product stream having first carbon chain lengths and the hydrogen; (d) supplying the unvaporized lower alkyl esters of the fatty acids having second carbon chain lengths remaining from step (a) to a second vaporization zone; (e) contacting the unvaporized lower alkyl esters having second carbon chain lengths in the second vaporization zone with an amount of hydrogen sufficient to vaporize the lower alkyl esters having fatty acids of the second carbon chain lengths into the hydrogen; (f) supplying the hydrogen and the vaporized lower alkyl esters of fatty acids having second carbon chain lengths to a second reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having second carbon chain lengths; (g) recovering from the second reaction zone an alcohol product stream having second carbon chain lengths and hydrogen; (h) separating the stream of fatty acid alcohol having the second carbon chain length from hydrogen; and (i) recycling a portion of the hydrogen recovered in step (h) to the first vaporization zone and a portion to the second vaporization zone.

公开(公告)号：US20120016163A1

公开(公告)日：2012-01-19

申请号：US13061904

申请日：2010-03-30

申请人： Donald Hugh McKinley ,  Andrew George Hiles ,  Rikard Umberto Andersson ,  John Richard Hensman

发明人： Donald Hugh McKinley ,  Andrew George Hiles ,  Rikard Umberto Andersson ,  John Richard Hensman

IPC分类号： C07C29/149

CPC分类号： C07C29/149 ,  Y02P20/132 ,  C07C31/125

摘要： A process for the co-production of a stream of a fatty alcohol having first carbon chain lengths and a stream of a fatty alcohol having a second carbon chain lengths, said second carbon chain lengths being longer than said first carbon chain lengths, said process comprising the steps of: (a) supplying a stream comprising lower alkyl esters of fatty acids having chain lengths comprising the first and second chain lengths to a first vaporisation zone and contacting said stream with an amount of hydrogen recycled from step (i) which is sufficient to vaporise the lower alkyl esters of the fatty acids having the first carbon chain lengths into the hydrogen; (b) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having the first carbon chain lengths to a first reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having first carbon chain lengths; (c) recovering from the first reaction zone an alcohol product stream having first carbon chain lengths and the hydrogen; (d) supplying the unvaporised lower alkyl esters of the fatty acids having second carbon chain lengths remaining from step (a) to a second vaporisation zone; (e) contacting the unvaporised lower alkyl esters having second carbon chain lengths in the second vaporisation zone with an amount of hydrogen sufficient to vaporise the lower alkyl esters having fatty acids of the second carbon chain lengths into the hydrogen; (f) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having second carbon chain lengths to a second reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having second carbon chain lengths; (g) recovering from the second reaction zone an alcohol product stream having second carbon chain lengths and hydrogen; (h) separating the stream of fatty acid alcohol having the second carbon chain length from hydrogen; and (i) recycling a portion of the hydrogen recovered in step (h) to the first vaporisation zone and a portion to the second vapourisation zone.

公开(公告)号：US06936727B2

公开(公告)日：2005-08-30

申请号：US10483524

申请日：2002-07-10

申请人： David Mark Sutton ,  Andrew George Hiles ,  Graham Reed ,  John Anthony Stannard

发明人： David Mark Sutton ,  Andrew George Hiles ,  Graham Reed ,  John Anthony Stannard

IPC分类号： C07B61/00 ,  C07D307/08

CPC分类号： C07D307/08

摘要： A process is described for the production of ethers, typically terahydrofuran, by reaction of a corresponding organic feed material selected from dicarboxylic acids and/or anhydrides, monoesters of dicarboxylic acids and/or anhydrides, diesters of dicarboxylic acids and/or anhydrides, lactones, and mixtures of two or more thereof in the presence of hydrogen which comprises the steps of: (a) supplying a stream comprising the organic feed material to a first vaporisation zone and contacting said feed with cycle gas comprising hydrogen such that at least a portion of the feed material is vaporised by and into the cycle gas; (b) supplying at least a portion of the cycle gas and the vaporised feed material to a first reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation and dehydration to occur; (c) recovering from the first reaction zone an intermediate product stream comprising unreacted feed material, cycle gas, desired product(s), and any co-products and by-products; (d) supplying the intermediate product stream to a second vaporisation zone and contacting it with additional feed material such that the said additional feed material is vaporised by and into the intermediate product stream; (e) supplying the product of step (d) to a subsequent reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation and, if required, dehydration to occur; and (f) recovering from the subsequent reaction zone a product stream comprising the ether.

摘要翻译： 描述了通过相应的选自二羧酸和/或酸酐的有机原料，二羧酸和/或酸酐的单酯，二羧酸和/或酸酐的二酯，内酯， 和其中两种或更多种在氢存在下的混合物，其包括以下步骤：（a）将包含有机进料的物流供应到第一蒸发区，并使所述进料与包含氢的循环气体接触，使得至少一部分 原料被循环气体蒸发并进入循环气体中; （b）将循环气体和蒸发的进料的至少一部分供应到包含催化剂并在反应条件下操作以允许氢化和脱水发生的第一反应区; （c）从第一反应区回收包含未反应的进料，循环气体，所需产物和任何副产物和副产物的中间产物流; （d）将中间产物流供应到第二蒸发区并使其与另外的进料相接触，使得所述另外的进料通过中间产物流蒸发并进入中间产物流; （e）将步骤（d）的产物供给到包含催化剂的后续反应区域中，并在反应条件下操作以允许氢化，如果需要，进行脱水发生; 和（f）从后续反应区回收包含醚的产物流。

公开(公告)号：US06239292B1

公开(公告)日：2001-05-29

申请号：US09554194

申请日：2000-06-28

申请人： Michael William Marshall Tuck ,  Michael Anthony Wood ,  Andrew George Hiles

发明人： Michael William Marshall Tuck ,  Michael Anthony Wood ,  Andrew George Hiles

IPC分类号： C07D30512

CPC分类号： C07D315/00 ,  C07C29/149 ,  C07C67/08 ,  C07C69/60 ,  C07C31/207

摘要： A process for the production of at least one C4 compound selected from 1,4-butanediol, gamma-butyrolactone and tetrahydrofuran, in which a solution of maleic anhydride in a high boiling ester is esterified with a C1 to C4 alcohol to form the corresponding maleate ester which is hydrogenated to form the at least one C4 compound. The specified high boiling ester has a boiling point which is about 30 degrees C. higher than that of the di-(C1-C4 alkyl)maleate.

摘要翻译： 制备选自1,4-丁二醇，γ-丁内酯和四氢呋喃中的至少一种C 4化合物的方法，其中马来酸酐在高沸点酯中的溶液用C1至C4醇酯化以形成相应的马来酸酯 酯，其被氢化以形成至少一种C 4化合物。 指定的高沸点酯的沸点比二（C 1 -C 4烷基）马来酸酯高约30摄氏度。

公开(公告)号：US6077964A

公开(公告)日：2000-06-20

申请号：US180766

申请日：1998-11-12

申请人： Michael William Marshall Tuck ,  Michael Anthony Wood ,  Andrew George Hiles

发明人： Michael William Marshall Tuck ,  Michael Anthony Wood ,  Andrew George Hiles

IPC分类号： B01J23/72 ,  C07B61/00 ,  C07C29/149 ,  C07C29/17 ,  C07C31/20 ,  C07D307/08 ,  C07D307/33 ,  C07D315/00 ,  C07C57/14

CPC分类号： C07D315/00 ,  C07C29/177 ,  C07D307/08

摘要： A process is described for the production of at least one C.sub.4 compound selected from butane-1,4-diol, .gamma.-butyrolactone and tetrahydrofuran, which includes the step of hydrogenation in the vapour phase of maleic anhydride in the presence of a heterogeneous hydrogenation catalyst, which process comprises:(a) contacting a vaporous stream containing maleic anhydride vapour, water vapour, and carbon oxides in an absorption zone with a high boiling organic solvent having a boiling point at atmospheric pressure which is at least about 30.degree. C. higher than that of maleic anhydride thereby to form a solution of maleic anhydride in the high boiling organic solvent;(b) recovering from the absorption zone a waste gas stream;(c) contacting the solution of maleic anhydride in the high boiling solvent with a gaseous stream containing hydrogen thereby to strip maleic anhydride therefrom and to form a vaporous stream comprising hydrogen and maleic anhydride;(d) contacting material of the vaporous stream of step (c) in a hydrogenation zone under hydrogenation conditions in the presence of a heterogeneous hydrogenation catalyst thereby to convert maleic anhydride to at least one C.sub.4 compound selected from butane-1,4-diol, .gamma.-butyrolactone and tetrahydrofuran; and(e) recovering from the hydrogenation zone a product stream containing said at least one C.sub.4 compound.

摘要翻译： PCT No.PCT / GB97 / 01286 Sec。 371日期：1998年11月12日 102（e）1998年11月12日日期PCT提交1997年5月12日PCT公布。 公开号WO97 / 43234 日期1997年11月20日描述了用于生产选自丁烷-1,4-二醇，γ-丁内酯和四氢呋喃中的至少一种C 4化合物的方法，其包括在存在下在马来酸酐的气相中氢化的步骤 的非均相氢化催化剂，该方法包括：（a）使吸收区中含有马来酸酐蒸气，水蒸气和碳氧化物的蒸汽流与沸点在大气压下的沸点高的有机溶剂接触，该有机溶剂至少约为 比马来酸酐高30℃，从而形成马来酸酐在高沸点有机溶剂中的溶液; （b）从吸收区回收废气流; （c）将马来酸酐在高沸点溶剂中的溶液与含有氢气的气流接触，从而从其中剥离马来酸酐并形成包含氢和马来酸酐的蒸气流; （d）在氢化条件下，在非均相加氢催化剂的存在下，将步骤（c）的气态物流接触于氢化区，从而将马来酸酐转化成至少一种选自丁烷-1,4-二醇， γ-丁内酯和四氢呋喃; 和（e）从氢化区回收含有所述至少一种C 4化合物的产物流。

公开(公告)号：US08278491B2

公开(公告)日：2012-10-02

申请号：US12681575

申请日：2008-10-03

申请人： Donald Hugh McKinley ,  Richard John Hensman ,  Andrew George Hiles ,  Rikard Umberto Andersson

发明人： Donald Hugh McKinley ,  Richard John Hensman ,  Andrew George Hiles ,  Rikard Umberto Andersson

IPC分类号： C07C29/149 ,  C07C27/04

CPC分类号： C07C29/149 ,  Y02P20/132 ,  C07C31/125

摘要： A process for the co-production of a stream of a fatty alcohol having first carbon chain lengths and a stream of a fatty alcohol having second carbon chain lengths, said second carbon chain lengths being longer than said first carbon chain lengths.

摘要翻译： 共同生产具有第一碳链长度的脂肪醇流和具有第二碳链长度的脂肪醇流的方法，所述第二碳链长度大于所述第一碳链长度。

公开(公告)号：US20100286454A1

公开(公告)日：2010-11-11

申请号：US12681575

申请日：2008-10-03

申请人： Donald Hugh McKinley ,  Richard John Hensman ,  Andrew George Hiles ,  Rikard Umberto Andersson

发明人： Donald Hugh McKinley ,  Richard John Hensman ,  Andrew George Hiles ,  Rikard Umberto Andersson

IPC分类号： C07C29/94

CPC分类号： C07C29/149 ,  Y02P20/132 ,  C07C31/125

摘要： A process for the co-production of a stream of a fatty alcohol having first carbon chain lengths and a stream of a fatty alcohol having a second carbon chain lengths, said second carbon chain lengths being longer than said first carbon chain lengths, said process comprising the steps of: (a) supplying a stream comprising lower alkyl esters of fatty acids having chain lengths comprising the first and second chain lengths to a first vaporisation zone and contacting said stream with an amount of hydrogen which is sufficient to vaporise the lower alkyl esters of the fatty acids having the first carbon chain lengths into the hydrogen; (b) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having the first carbon chain lengths to a first reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having first carbon chain lengths; (c) recovering from the first reaction zone an alcohol product stream having first carbon chain lengths and hydrogen; (d) separating the stream of fatty alcohol having the first carbon chain lengths from hydrogen; (e) supplying the unvaporised lower alkyl esters of the fatty acids having second carbon chain lengths remaining from step (a) to a second vaporisation zone; (f) contacting the unvaporised lower alkyl esters having second carbon chain lengths in the second vaporisation zone with hydrogen recovered in step (d) and an additional amount of hydrogen such that the total amount of hydrogen is sufficient to vaporise the lower alkyl esters having fatty acids of the second carbon chain lengths into the hydrogen; (g) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having second carbon chain lengths to a second reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having second carbon chain lengths; and (h) recovering from the second reaction zone an alcohol product stream having second carbon chain lengths and hydrogen.

公开(公告)号：US07598404B2

公开(公告)日：2009-10-06

申请号：US10582370

申请日：2004-12-01

申请人： Adrian Francis Backes ,  Andrew George Hiles ,  David Mark Sutton

发明人： Adrian Francis Backes ,  Andrew George Hiles ,  David Mark Sutton

IPC分类号： C07D307/08

CPC分类号： C07D307/08

摘要： A process for the production of an ether optionally with a diol and/or a lactone, by reaction of a corresponding organic feed material selected from unsaturated dicarboxylic acids and/or anhydrides, mono-esters of unsaturated dicarboxylic acids and/or anhydrides, diesters of unsaturated dicarboxylic acids and/or anhydrides, unsaturated lactones, and mixtures of two or more thereof in the presence of hydrogen which comprises the steps of-(a) supplying a stream comprising at least a portion of the organic feed material to a pre-reactor zone comprising catalyst and operating under reaction conditions and contacting said feed with a hydrogen containing stream such that at least some of the carbon carbon double bonds are saturated; (b) vaporising the at least partly saturated feed into the hydrogen containing stream in a vaporizing zone; (c) supplying the hydrogen-containing stream containing the vaporized at least partially saturated feed to a reaction zone comprising catalyst and operating under reaction conditions; (d) recovering from the reaction zone a product stream comprising the ether and optionally diol and/or lactone; and (e)recycling depleted hydrogen-containing stream to at least the pre-reactor zone or the vaporization zone.

摘要翻译： 通过相应的选自不饱和二羧酸和/或酸酐的有机原料，不饱和二羧酸和/或酸酐的单酯和/或酸酐的二酯的二酯与二醇和/或内​​酯生产醚的方法 不饱和二羧酸和/或酸酐，不饱和内酯及其两种或多种在氢存在下的混合物，其包括以下步骤：（a）将包含至少一部分有机原料的料流供应至预反应器 区域，其包含催化剂并在反应条件下操作并使所述进料与含氢气流接触，使得至少一些碳碳双键饱和; （b）将所述至少部分饱和的进料蒸发到蒸发区中的含氢流中; （c）将含有蒸发的至少部分饱和的进料的含氢流供应到包含催化剂并在反应条件下操作的反应区; （d）从反应区回收包含醚和任选的二醇和/或内​​酯的产物流; 和（e）将耗尽的含氢物流再循环到至少预反应器区或蒸发区。