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公开(公告)号:US07534790B2
公开(公告)日:2009-05-19
申请号:US11944282
申请日:2007-11-21
申请人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
发明人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
IPC分类号: A61K31/5375 , A61K31/5377 , A61K31/495 , A61K31/426 , A61K31/403 , A61K31/4015 , A61K31/40 , C07D295/033 , C07D413/02 , C07D295/027 , C07D277/04 , C07D209/96 , C07D207/12
CPC分类号: C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译: 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途,包括治疗心律失常和产生镇痛和局部麻醉。
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公开(公告)号:US07101877B2
公开(公告)日:2006-09-05
申请号:US10674684
申请日:2003-09-29
申请人: Allen I Bain , Gregory N Beatch , Cindy J Longley , Bertrand M C Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L Yong , Jeff Jiqun Zhu , Alexander B Zolotoy
发明人: Allen I Bain , Gregory N Beatch , Cindy J Longley , Bertrand M C Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L Yong , Jeff Jiqun Zhu , Alexander B Zolotoy
IPC分类号: A61K31/5377 , C07D413/14
CPC分类号: C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
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公开(公告)号:US07875611B2
公开(公告)日:2011-01-25
申请号:US12424450
申请日:2009-04-15
申请人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
发明人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
IPC分类号: A61K31/5375 , A61K31/40 , C07D265/30 , C07D207/04
CPC分类号: C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译: 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途,包括治疗心律失常和产生镇痛和局部麻醉。
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公开(公告)号:US20100029639A1
公开(公告)日:2010-02-04
申请号:US12424450
申请日:2009-04-15
申请人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
发明人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
IPC分类号: A61K31/5377 , C07D265/32 , A61K31/5375 , A61K31/40 , C07D207/08 , C07D409/08 , A61P9/00
CPC分类号: C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译: 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途,包括治疗心律失常和产生镇痛和局部麻醉。
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公开(公告)号:US5437602A
公开(公告)日:1995-08-01
申请号:US107324
申请日:1993-08-13
CPC分类号: A61B90/40 , A61B2090/401 , A61B46/27 , Y10S128/24
摘要: A flexible isolator bag used to isolate a controlled therapeutic gas atmosphere about a human limb for the management and treatment of wounds and lesions, or an amputation, has a discharge port and a flexible manifold section providing an intake manifold which has an infeed port and inlet openings to the interior of the bag. A self-sealing zipper extends along part of the length of the bag. The bag is secured to the patient by adhesive tape applied to the rim of the open end of the bag. This rim is shaped to prevent a tourniquet effect.
摘要翻译: 用于隔离围绕人肢的受控治疗气体环境的柔性隔离袋用于管理和治疗伤口和损伤或截肢,具有排出口和柔性歧管部分,其提供具有进料口和入口的进气歧管 到袋子内部的开口。 自密封拉链沿袋的长度的一部分延伸。 袋子通过施加到袋的开口端的边缘的胶带固定到患者身上。 该边缘成形为防止止血带效应。
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公开(公告)号:US20110207730A1
公开(公告)日:2011-08-25
申请号:US12970532
申请日:2010-12-16
申请人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M.C. Plouvier , Tao Sheng , Michael J.A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
发明人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M.C. Plouvier , Tao Sheng , Michael J.A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
IPC分类号: A61K31/5377 , C07D265/30 , A61K31/5375 , C07D207/325 , A61K31/40 , C07D413/02 , C07C211/38 , A61K31/135 , C07D241/06 , A61K31/4965 , C07D491/113 , A61K31/438 , C07D277/24 , A61K31/426 , A61P9/00 , C12N5/071
CPC分类号: C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译: 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途,包括治疗心律失常和产生镇痛和局部麻醉。
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