公开(公告)号：US20230330665A1

公开(公告)日：2023-10-19

申请号：US18184326

申请日：2023-03-15

Applicant: Douglas B. Dority ,  Alan E. Tucker

Inventor： Douglas B. Dority ,  Alan E. Tucker

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L3/502738 ,  B01L3/502761 ,  B01L2200/04 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0864 ,  B01L2400/0487 ,  B01L2400/0644

Abstract: Improved sample cartridges, valve assemblies and methods of manufacture and assembly are provided herein. Such systems can include a sample processing cartridge having a unitary cartridge body with integral syringe tube and valve interface. Such systems can further includes valve assemblies with an overmolded gasket and gaskets with a protruding conical valve sealing surface. Various additional features can include thin film sealing for cartridge as well as valve assemblies for chemical lysis. Thin film sealing for cartridge lids can include various multi-layered designs to facilitate injection and sealing of reagents within the cartridge. Magnetic separation features are also included. Such features can be included in various design iterations as needed for compatibility with existing technologies and to accommodate needs for manufacturing workflows.