公开(公告)号：US07566742B2

公开(公告)日：2009-07-28

申请号：US10531435

申请日：2003-10-20

申请人： Patrick Joseph Silcock ,  Lynton Alexander Bridger ,  Adrian Stewart Denham Kerr ,  Martin Mitchell Ferguson ,  Jean-Pierre Ghislain Dufour

发明人： Patrick Joseph Silcock ,  Lynton Alexander Bridger ,  Adrian Stewart Denham Kerr ,  Martin Mitchell Ferguson ,  Jean-Pierre Ghislain Dufour

IPC分类号： A23J3/10 ,  A61K6/00 ,  A61K47/42 ,  A61K38/00

CPC分类号： C12Y203/02013 ,  A23J3/10 ,  A23L27/79 ,  A23P20/20 ,  A23V2002/00 ,  A61K9/006 ,  A23V2250/54246 ,  A23V2250/1618 ,  A23V2250/1578 ,  A23V2250/1644 ,  A23V2250/242 ,  A23V2250/6406 ,  A23V2200/222

摘要： The invention provides, in one aspect, compositions for delivering a bioactive metal ion to a mammal, the compositions comprising (a) an effective amount of a source of the bioactive metal ion, (b) a phosphoprotein preparation obtained by partially cross linking a partial hydrolysate of casein or a caseinate, and (c) one or more physiologically acceptable diluents or carriers. Also provided are compositions for remineralising tooth enamel and/or for treating or preventing dental caries, tooth erosion, dentinal hypersensitivity or gingivitis in a mammal, wherein the compositions comprise an effective amount of such a phosphoprotein preparation, in combination with one or more carriers or diluents. In related aspects, the invention provides methods of using such compositions. Also provided are novel phosphoprotein preparations suitable for use in such compositions and methods.

摘要翻译： 本发明在一个方面提供了用于将生物活性金属离子递送至哺乳动物的组合物，所述组合物包含（a）有效量的生物活性金属离子源，（b）通过部分交联部分 酪蛋白或酪蛋白酸盐的水解产物，和（c）一种或多种生理上可接受的稀释剂或载体。 还提供了用于再矿化牙釉质和/或用于治疗或预防哺乳动物中的龋齿，牙齿侵蚀，牙质过敏或牙龈炎的组合物，其中所述组合物包含有效量的这种磷蛋白制剂，与一种或多种载体或 稀释剂。 在相关方面，本发明提供了使用这种组合物的方法。 还提供了适用于这种组合物和方法的新型磷蛋白制剂。

公开(公告)号：US07056542B1

公开(公告)日：2006-06-06

申请号：US10182225

申请日：2000-01-27

申请人： Lynton Alexander Bridger ,  Adrian Stewart Denham Kerr ,  Jean-Pierre Ghislain Dufour ,  Patrick Joseph Silcock ,  Stephanie Therese Vincent

发明人： Lynton Alexander Bridger ,  Adrian Stewart Denham Kerr ,  Jean-Pierre Ghislain Dufour ,  Patrick Joseph Silcock ,  Stephanie Therese Vincent

IPC分类号： A23G3/30

CPC分类号： A23G4/064 ,  A23G4/08 ,  A23G4/16 ,  A23L29/10

摘要： The invention relates to chewable gum base compositions, to chewing gums containing them, and to processes for preparing them. The gum base compositions comprise (a) a polyvinyl acetate matrix, in which the polyvinyl acetate is in the form of a continuous phase, and (b) casein, a modified casein, or both casein and a modified casein, wherein particles of casein and/or modified casein are dispersed throughout the polyvinyl acetate matrix.In preferred embodiments the gum base compositions also contain polyglycerol polyricinoleate, mono- and di-glycerides esterified with mono-acetyl and di-acetyl tartaric acid, acetylated monoglycerides, lecithin and sodium or calcium stearoyl-2-lactylate. Chewing gums of the present invention contain a chewable gum base as described above, in combination with one or more sweeteners and/or flavouring agents, and preferably also glycerol triacetate and stearic acid.

摘要翻译： 本发明涉及咀嚼型胶基组合物，含有它们的口香糖及其制备方法。 胶基组合物包含（a）聚乙酸乙烯酯基质，其中聚乙酸乙烯酯为连续相的形式，和（b）酪蛋白，改性酪蛋白或酪蛋白和改性酪蛋白，其中酪蛋白和 /或改性酪蛋白分散在整个聚乙酸乙烯酯基质中。 在优选实施方案中，胶基组合物还含有聚甘油聚蓖麻油酸酯，单乙酰和二乙酰酒石酸酯，乙酰化单甘油酯，卵磷脂和硬脂酰-2-乳酸钠或钙酯化的单甘油酯和二甘油酯。 本发明的口香糖含有如上所述的可咀嚼的胶基，与一种或多种甜味剂和/或调味剂组合，优选还含有甘油三乙酸酯和硬脂酸。