发明授权
US07566742B2 Phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation
失效
用于生物活性金属离子输送和牙齿再矿化的磷蛋白制剂
- 专利标题: Phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation
- 专利标题(中): 用于生物活性金属离子输送和牙齿再矿化的磷蛋白制剂
-
申请号: US10531435申请日: 2003-10-20
-
公开(公告)号: US07566742B2公开(公告)日: 2009-07-28
- 发明人: Patrick Joseph Silcock , Lynton Alexander Bridger , Adrian Stewart Denham Kerr , Martin Mitchell Ferguson , Jean-Pierre Ghislain Dufour
- 申请人: Patrick Joseph Silcock , Lynton Alexander Bridger , Adrian Stewart Denham Kerr , Martin Mitchell Ferguson , Jean-Pierre Ghislain Dufour
- 代理机构: Knobbe Martens Olson & Bear LLP
- 优先权: NZ522071 20021018
- 国际申请: PCT/NZ03/00232 WO 20031020
- 国际公布: WO2004/035077 WO 20040429
- 主分类号: A23J3/10
- IPC分类号: A23J3/10 ; A61K6/00 ; A61K47/42 ; A61K38/00
摘要:
The invention provides, in one aspect, compositions for delivering a bioactive metal ion to a mammal, the compositions comprising (a) an effective amount of a source of the bioactive metal ion, (b) a phosphoprotein preparation obtained by partially cross linking a partial hydrolysate of casein or a caseinate, and (c) one or more physiologically acceptable diluents or carriers. Also provided are compositions for remineralising tooth enamel and/or for treating or preventing dental caries, tooth erosion, dentinal hypersensitivity or gingivitis in a mammal, wherein the compositions comprise an effective amount of such a phosphoprotein preparation, in combination with one or more carriers or diluents. In related aspects, the invention provides methods of using such compositions. Also provided are novel phosphoprotein preparations suitable for use in such compositions and methods.
公开/授权文献
信息查询