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1.发明授权公开(公告)号：US11680073B2
公开(公告)日：2023-06-20
申请号：US17511265
申请日：2021-10-26
Applicant: ADT PHARMACEUTICALS, LLC
Inventor： Michael Boyd , Xi Chen
IPC: C07F5/02 , C07C235/32 , C07D213/40 , C07D213/56 , C07D231/40 , C07D261/08 , C07D277/28 , C07D307/52 , C07D317/12 , C07D327/04
CPC classification number: C07F5/025 , C07C235/32 , C07D213/40 , C07D213/56 , C07D231/40 , C07D261/08 , C07D277/28 , C07D307/52 , C07D317/12 , C07D327/04 , C07B2200/07
Abstract: Disclosed are compounds for medical uses, for example, compounds of formula Ia,
wherein A1, A2, A3, A4, A5, A6, A7, R6, R7 and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.-
公开(公告)号：US11130744B2
公开(公告)日：2021-09-28
申请号：US16834348
申请日：2020-03-30
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: A61K31/341 , A61K31/36 , A61K31/40 , A61K31/401 , A61K31/44 , A61K31/445 , A61K45/06 , C07C233/58 , C07C235/32 , C07C237/20 , C07D207/14 , C07D207/337 , C07D211/56 , C07D213/24 , C07D213/75 , C07D235/30 , C07D307/38 , C07D307/52 , C07D307/54 , C07D317/64 , C07D405/12
Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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公开(公告)号：US20200031795A1
公开(公告)日：2020-01-30
申请号：US16593806
申请日：2019-10-04
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: C07D317/64 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/401 , A61K31/36 , A61K31/341 , C07D211/56 , C07D213/75 , C07D207/14 , C07D207/337 , C07D307/54 , C07C235/32 , C07C237/20 , C07D235/30 , C07D405/12 , C07D213/24 , C07D307/38 , C07D307/52 , A61K45/06 , C07C233/58
Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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公开(公告)号：US10975054B2
公开(公告)日：2021-04-13
申请号：US16593776
申请日：2019-10-04
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: C07D317/64 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/401 , A61K31/36 , A61K31/341 , C07D211/56 , C07D213/75 , C07D207/14 , C07D207/337 , C07D307/54 , C07C235/32 , C07C237/20 , C07D235/30 , C07D405/12 , C07D213/24 , C07D307/38 , C07D307/52 , A61K45/06 , C07C233/58
Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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公开(公告)号：US20200223815A1
公开(公告)日：2020-07-16
申请号：US16834267
申请日：2020-03-30
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: C07D317/64 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/401 , A61K31/36 , A61K31/341 , C07D211/56 , C07D213/75 , C07D207/14 , C07D207/337 , C07D307/54 , C07C235/32 , C07C237/20 , C07D235/30 , C07D405/12 , C07D213/24 , C07D307/38 , C07D307/52 , A61K45/06 , C07C233/58
Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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Patent Agency Ranking
公开(公告)号：US20220315553A1
公开(公告)日：2022-10-06
申请号：US17835551
申请日：2022-06-08
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: C07D317/64 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/401 , A61K31/36 , A61K31/341 , C07D211/56 , C07D213/75 , C07D207/14 , C07D207/337 , C07D307/54 , C07C235/32 , C07C237/20 , C07D235/30 , C07D405/12 , C07D213/24 , C07D307/38 , C07D307/52 , A61K45/06 , C07C233/58
Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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7.发明申请公开(公告)号：US20210261572A1
公开(公告)日：2021-08-26
申请号：US17047787
申请日：2019-04-26
Applicant: ADT PHARMACEUTICALS, LLC
Inventor： Michael BOYD , Xi CHEN
IPC: C07F5/02 , C07D307/52 , C07D213/40 , C07C235/32 , C07D213/56 , C07D261/08 , C07D277/28 , C07D317/12 , C07D327/04 , C07D231/40
Abstract: Disclosed are compounds for medical uses, for example, compounds of formula (Ia), wherein A1, A2, A3, A4, A5, A6, A7, R6, R7 and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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公开(公告)号：US10981886B2
公开(公告)日：2021-04-20
申请号：US16593806
申请日：2019-10-04
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: C07D317/64 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/401 , A61K31/36 , A61K31/341 , C07D211/56 , C07D213/75 , C07D207/14 , C07D207/337 , C07D307/54 , C07C235/32 , C07D237/20 , C07D235/30 , C07D405/12 , C07D213/24 , C07D307/38 , C07D307/52 , A61K45/06 , C07C233/58 , C07C237/20
Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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公开(公告)号：US20200223817A1
公开(公告)日：2020-07-16
申请号：US16837757
申请日：2020-04-01
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: C07D317/64 , C07D307/52 , C07C235/34 , C07D213/75 , C07D207/14 , C07D213/40 , C07D207/335 , C07C311/29 , A61K31/165 , A61K31/216 , A61K31/421 , A61K31/4402 , A61K31/4406 , A61K31/496 , A61K31/5375 , A61K31/5377 , C07C235/32 , C07C237/20 , C07D213/24 , C07D235/30 , C07D307/38 , C07D405/12 , A61K31/401 , A61K31/167 , A61K31/341 , A61K31/40 , A61K45/06 , G01N33/574 , A61K31/36 , A61K31/44 , A61K31/445 , C07C233/58 , C07D207/337 , C07D211/56 , C07D307/54
Abstract: Disclosed are compounds, for example, a compound of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition for example, cancer, mediated by the ras gene.
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公开(公告)号：US20200223816A1
公开(公告)日：2020-07-16
申请号：US16834348
申请日：2020-03-30
Applicant: ADT Pharmaceuticals, LLC
Inventor： Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
IPC: C07D317/64 , A61K31/445 , A61K31/44 , A61K31/40 , A61K31/401 , A61K31/36 , A61K31/341 , C07D211/56 , C07D213/75 , C07D207/14 , C07D207/337 , C07D307/54 , C07C235/32 , C07C237/20 , C07D235/30 , C07D405/12 , C07D213/24 , C07D307/38 , C07D307/52 , A61K45/06 , C07C233/58
Abstract: Disclosed are compounds, for example, compounds of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.
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