公开(公告)号：US12230399B2

公开(公告)日：2025-02-18

申请号：US17762125

申请日：2020-09-28

Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.

Inventor： Faisal Mahmood ,  Richard Chen

IPC: G16H50/20 ,  G06T7/00 ,  G06V10/80 ,  G06V20/69 ,  G16B30/00 ,  G16B40/20

Abstract: Systems and methods can quantify the tumor microenvironment for diagnosis, prognosis and therapeutic response prediction by fusing different data types (e.g., morphological information from histology and molecular information from omics) using an algorithm that harnesses deep learning. The algorithm employs tensor fusion to provide end-to-end multimodal fusion to model the pairwise interactions of features across multiple modalities (e.g., histology and molecular features) and deep learning. The systems and methods improve upon traditional methods for quantifying the tumor microenvironment that rely on concatenation of extracted features.

公开(公告)号：US12229260B1

公开(公告)日：2025-02-18

申请号：US18337890

申请日：2023-06-20

Applicant: NORTHROP GRUMMAN SYSTEMS CORPORATION

Inventor： Carlos A. Villegas

IPC: G06F21/00 ,  G06F12/14 ,  G06F21/56 ,  G06F21/64

Abstract: In some examples, an analyzer manager configured to select one of a program code analyzer, a static data analyzer, and an unused memory location analyzer for malware detection within memory of a system. The program code analyzer can be executed to evaluate instruction data for executing a computer program at a first set of memory locations within the memory for malware in response to being selected by the analyzer manager. The static data analyzer can be executed to evaluate static data for use by the computer program at a second set of memory locations within the memory for the malware in response to being selected by the analyzer manager. The unused memory location analyzer can be executed to evaluate null data indicative of unused memory locations at a third set of memory locations within the memory for the malware in response to being selected by the analyzer manager.

公开(公告)号：US12229083B2

公开(公告)日：2025-02-18

申请号：US17711021

申请日：2022-03-31

Applicant: Inventus Holdings, LLC

Inventor： Amir Liberman ,  Hooman Yousefizadeh ,  Linga Murthy Manchala ,  Jeroen Leverman

IPC: G06F16/13 ,  G06F9/54 ,  G06F16/172

Abstract: An indexer retrieves a set of messages generated by a given data source of a plurality of data sources from a data storage. The indexer also processes the set of messages to generate processed data for the given data source and stores the processed data in a cache. The processed data includes a data file with data from the given data source and an index file identifying a location of the data file. The indexer determines when the processed data for the given generation source reaches a threshold size. The indexer also stores the data file of the processed data in the data storage and updates the index file for the processed data to identify the data storage as the location of the data file.

公开(公告)号：US12227605B2

公开(公告)日：2025-02-18

申请号：US18559450

申请日：2022-05-12

Applicant: BOREALIS AG

Inventor： Norbert Reichelt

IPC: C08F255/02 ,  C08J3/20 ,  C08J3/28 ,  C08K5/09

Abstract: The present invention is related to a high melt strength polypropylene (HMS-PP) comprising units derivable from at least one polyunsaturated fatty acid, a process for preparing said high melt strength polypropylene (HMS-PP), as well as an article comprising said high melt strength polypropylene (HMS-PP).

公开(公告)号：US12227159B2

公开(公告)日：2025-02-18

申请号：US17400210

申请日：2021-08-12

Applicant: ZF Active Safety US Inc.

Inventor： Blaise J. Ganzel

IPC: B60T8/176 ,  B60T7/04 ,  B60T8/40 ,  B60T13/68

Abstract: A fluid separator includes a separator housing defining a longitudinal bore having first and second bore ends. A first fluid passage is in fluid communication with the bore at the first bore end. A second fluid passage is in fluid communication with the bore adjacent the second bore end. A third fluid passage is in fluid communication with a portion of the bore spaced apart from both the first and second bore ends. A free-floating piston is located inside the bore and configured for longitudinal movement with respect to the bore responsive to fluid pressure within the bore. A biasing spring urges the piston toward the second bore end. An end cap is located at the second bore end. The end cap is maintained on the housing via at least two retainers.

公开(公告)号：US12224088B2

公开(公告)日：2025-02-11

申请号：US17608559

申请日：2020-04-30

Applicant: LEONI KABEL GMBH

Inventor： Sebastian Stengl ,  Guenter Koenig

IPC: H01B9/04 ,  B60L53/12 ,  H01B1/02 ,  H01B7/32

Abstract: A coaxial cable includes a non-conductive core and a first flexible copper conductor which surrounds the non-conductive core and is used as an inner conductor of the coaxial cable. Insulation is provided around the first flexible copper conductor. A second flexible copper conductor which surrounds the insulation and serves as an outer conductor of the coaxial cable.

公开(公告)号：US12222066B2

公开(公告)日：2025-02-11

申请号：US17688850

申请日：2022-03-07

Applicant: ZHEJIANG TOPMB ELECTRICAL LIGHTING CO., LTD

Inventor： Lingling Pang

IPC: G06F1/16 ,  F16M11/04 ,  F16M11/10 ,  F16M13/02

Abstract: The present invention discloses a fixing clip, which comprises an article connection structure, a first clamping body, a second clamping body and a counterweight structure arranged in sequence. The article connection structure is arranged on the first clamping body; the second clamping body and the first clamping body are relatively slidably connected to form a first clamping interval with adjustable clamping width; the end of the second clamping body is provided with a counterweight structure connecting piece, and the counterweight structure is installed on the counterweight structure connecting piece, wherein the counterweight structure and the counterweight structure connecting piece can be relatively rotated or fixed; the first clamping body includes a first clamping portion and a first sliding connection portion, and the first clamping portion and the first sliding connection portion form a clamping angle. The fixing clip comprises an adjusting cover.

公开(公告)号：US12218658B2

公开(公告)日：2025-02-04

申请号：US17768732

申请日：2020-10-14

Applicant: LEONI BORDNETZ-SYSTEME GMBH

Inventor： Matthias Ebert ,  Wolfgang Koch ,  Martin Roesler

IPC: G01R31/26 ,  G01R31/327 ,  H03K17/18

Abstract: A system and a method for identifying a non-switching semiconductor switch are proposed. The system has a first acquisition component, a second acquisition component and a determination unit. The first acquisition component is designed to acquire a profile of an electrical variable of a first semiconductor switch driven by way of a first drive signal. The second acquisition component is designed to acquire a profile of an electrical variable of a second semiconductor switch driven by way of a second drive signal and connected in parallel with the first semiconductor switch. The determination unit is designed to use the profile of the electrical variable of the first semiconductor switch and the profile of the electrical variable of the second semiconductor switch as a basis for determining an output signal that allows identification of a non-switching semiconductor switch for the first semiconductor switch and/or the second semiconductor switch.

公开(公告)号：US12210189B2

公开(公告)日：2025-01-28

申请号：US18479418

申请日：2023-10-02

Applicant: NORTHROP GRUMMAN SYSTEMS CORPORATION

Inventor： Mark William Knight ,  Stephanie Roxane Sandor-Leahy ,  Lakshminarayanan Ravi Narasimhan

IPC: G02B6/136 ,  G02B6/12

Abstract: A method of making a photonic integrated circuit (PIC) is provided. The method comprises depositing a functional resist material layer over a substrate, disposing and pressing a stamp with a plurality of nanopatterns into the functional resist material for a period of time, and removing the stamp from the functional resist material to provide nanofeatures that are inverted versions of the nanopatterns, wherein the nanofeatures form one or more optical elements.

公开(公告)号：US12210019B2

公开(公告)日：2025-01-28

申请号：US17072076

申请日：2020-10-16

Applicant: Case Western Reserve University

Inventor： Aaron Weinberg ,  Santosh Ghosh ,  Umut A. Gurkan

IPC: G01N33/574 ,  G01N33/543

Abstract: A method of detecting epithelial cancer is described that includes the steps of: (a) determining the level of beta defensin 3 (BD-3) and beta defensin 2 (BD-2) in a suspect sample obtained from a subject; (b) comparing the level of BD-3 to BD-2 determined in the suspect sample to obtain a suspect BD-3/BD-2 ratio, (c) comparing the suspect BD-3/BD-2 ratio to a healthy BD-3/BD-2 ratio to obtain a diagnostic BD-3/BD-2 ratio; and (d) characterizing the subject as having epithelial cancer if the diagnostic BD-3/BD-2 ratio is greater than 1. A microfluidic device for detecting epithelial cancer using the diagnostic BD-3/BD-2 ratio is also described.